Protein Alignment CG1129 and Eif2b3

DIOPT Version :9

• Sequence 1: NP_001189177.2
• Gene: CG1129 / 40599
• FlyBaseID: FBgn0037279
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_001104747.1
• Gene: Eif2b3 / 108067
• MGIID: 1313286
• Length: 452
• Species: Mus musculus
• Alignment Length: 447
• Identity: 101/447 - (22%)
• Similarity: 178/447 - (39%)
• Gaps: 115/447 - (25%)

  Fly    12 RALILVGGYGTRLRPLTLSTPKPLVEFANKPILLHQLEALVDAGCRQVILAVSYRAEQMEKELKV 76
            :|:::..|.|:|:..||.|.||||:...|||::.:.|..|...|..:||:..:   :.::|.|..
Mouse     4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT---KDVQKALCA 65

  Fly    77 EAK-KLGVELIFSHETEPLGTAGPLALAKTILAASSEPFFVLNSDVICDFPFKQLVQFHCNHGKE 140
            |.| |:.::::...:...:|||..|   :.|.........||:.|:|.|....::|.....:...
Mouse    66 EFKMKMKLDIVCIPDEADMGTADSL---RHIYPKLKTDVLVLSCDLITDVALHEVVDLFRAYDAS 127

  Fly   141 GTIVVTK-----------------VEEPSKYGV------VLY-------DENGCIKNFI--EKPQ 173
            ..:::.|                 ||:....||      :|:       ||...||..|  :.|:
Mouse   128 LAMLMRKGQESIEPVPGQKGKKKPVEQRDFIGVDSTGKRLLFMANEADLDEELVIKGSILQKHPR 192

  Fly   174 -EFVSNKINAGIYIFNPSVLDRI--EVKPTSIEKEVFPEMTQQQ--------------------E 215
             .|.:..::|.:|.....|:|.:  ....|||..|:.|.:.::|                    |
Mouse   193 IHFHTGLVDAHLYCLKKYVVDFLMENRSITSIRSELIPYLVRKQFSSASSQQRQEDKEEDLKKKE 257

  Fly   216 LYAMDLTGF-----------------------WMDI--GQPKDFL----TGMCLYLSSL-----R 246
            |.::|:..|                       |.|:  .|.:.::    .|:|..:|:|     .
Mouse   258 LKSLDIYSFIKKDDTLTLAPYDACWNAFRGDKWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEA 322

  Fly   247 QKQSPKLYTGPGVVGNVL------VDPTAKIGEGCRIGPNVTIGPDVVIEDGVCIKRSTILKGAI 305
            .:|.|||.       :||      :..:|:|.....||.:..||||..|.:...||.|.|....:
Mouse   323 NRQVPKLL-------SVLCPEESMIHSSAQIVNKHLIGADSLIGPDTQIGEKSSIKHSVIGSSCV 380

  Fly   306 VRSHSWLDSCIVGWRSTVGRWVRIEGITVLGEDVI-----VKDELYINGGQVLPHKS 357
            :|..:.:.:|::....||.....|.|..:....||     :|:.| :..||.:..|:
Mouse   381 IRDRTSITNCLLMNSVTVEEGSSIHGSVICNNAVIETGAEIKNCL-VGSGQRIEAKA 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1129	NP_001189177.2	GCD1	12..361	CDD:224129	101/447 (23%)
		M1P_guanylylT_B_like_N	12..242	CDD:133047	67/314 (21%)
		LbetaH	264..343	CDD:294107	22/89 (25%)
Eif2b3	NP_001104747.1	eIF-2B_gamma_N	3..212	CDD:133041	50/213 (23%)
		GCD1	4..447	CDD:224129	101/447 (23%)
		LbH_eIF2B_gamma_C	357..437	CDD:100057	22/81 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810