Protein Alignment Hus1-like and HUS1

DIOPT Version :9

• Sequence 1: NP_001262267.1
• Gene: Hus1-like / 40598
• FlyBaseID: FBgn0026417
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_004498.1
• Gene: HUS1 / 3364
• HGNCID: 5309
• Length: 280
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 89/290 - (30%)
• Similarity: 147/290 - (50%)
• Gaps: 25/290 - (8%)

  Fly     1 MKFRALMQDPLYMKEFQAIVATLTKLAKDCVMILGSRQMHFIVNEDQSSAASPLVWAGITAEEYF 65
            |||||.:.|...:..|..|...:.||||.|.:.:...:::||:. |:.:.....:|..:..|.:|
Human     1 MKFRAKIVDGACLNHFTRISNMIAKLAKTCTLRISPDKLNFILC-DKLANGGVSMWCELEQENFF 64

  Fly    66 PEYRMEAAHPDQEYIVLGVSSANLGRALSVLRGGGVNSCKLKLQRIQFPCISVIASVLTSSSTEA 130
            .|::||....:...|.|.::|.||.|||...:  ...:.|:||....|||::|...:|:.||: :
Human    65 NEFQMEGVSAENNEIYLELTSENLSRALKTAQ--NARALKIKLTNKHFPCLTVSVELLSMSSS-S 126

  Fly   131 REVVHDVPVTIIPGSDWSAYVVPRVPNSQLALGLPSLRLLKSLIDKLKNISPSLEFQVNVDGELN 195
            |.|.||:|:.:||...|.....|.||:..:::.||.|:.:||:::|:||||..|..:.|:|||||
Human   127 RIVTHDIPIKVIPRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNHLVIEANLDGELN 191

  Fly   196 VIATSEMSTVTSRFQKLLIRTVSGSQQEASCS--------------VDSRKASAFFGALQLPNEE 246
            :...:|:..||:.|:.|      |:...||.|              :|.||...|....|:...:
Human   192 LKIETELVCVTTHFKDL------GNPPLASESTHEDRNVEHMAEVHIDIRKLLQFLAGQQVNPTK 250

  Fly   247 LTIGIDREHSIHLQIDVRQDVVLHSILPAV 276
            ....|.....:|..: :.:||.|...:||:
Human   251 ALCNIVNNKMVHFDL-LHEDVSLQYFIPAL 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hus1-like	NP_001262267.1	Hus1	1..277	CDD:281934	89/290 (31%)
HUS1	NP_004498.1	Hus1	1..280	CDD:397902	89/290 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149463
Domainoid	1	1.000	138	1.000	Domainoid score	I4847
eggNOG	1	0.900	-	-		E1_KOG3999
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37932
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4529
Isobase	1	0.950	-	0	Normalized mean entropy	S5411
OMA	1	1.010	-	-		QHG54444
OrthoDB	1	1.010	-	-		D1053181at2759
OrthoFinder	1	1.000	-	-		FOG0003934
OrthoInspector	1	1.000	-	-		otm41269
orthoMCL	1	0.900	-	-		OOG6_102922
Panther	1	1.100	-	-	LDO	PTHR12900
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R579
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750