Protein Alignment ctrip and HUL5

DIOPT Version :9

• Sequence 1: NP_001189170.1
• Gene: ctrip / 40596
• FlyBaseID: FBgn0260794
• Length: 3140
• Species: Drosophila melanogaster
• Sequence 2: NP_011374.1
• Gene: HUL5 / 852736
• SGDID: S000003109
• Length: 910
• Species: Saccharomyces cerevisiae
• Alignment Length: 597
• Identity: 135/597 - (22%)
• Similarity: 227/597 - (38%)
• Gaps: 144/597 - (24%)

  Fly  2561 HLLFYATSFDRDRALQRLLDTTPDLNAAESSERVAPRLDRRK-----RAISRTEILKQAEHILQD 2620
            :|.||       ..||...|...:....||.|.:...:|..|     :::...::.|:.:..|:
Yeast   441 NLRFY-------EELQEYEDLYREHLEEESDEDMEKEIDLDKERPPLKSLLLNKMKKRLKSSLR- 497

  Fly  2621 FGHSKALLE----IQYENEVGTGLGPTLEFYALVSAELQRTDLGLWNGSDSYKQNSVTIVDVVKA 2681
            |...:.|||    |.:|..|..       ||..::.:.:|
Yeast   498 FRKLEILLELPFFIPFEERVDL-------FYMFIALDKKR------------------------- 530

  Fly  2682 NSAVLHIEDALEATTTDQNTPAVAGASLVSSSTTTTTTTAQQHQHPPTRSSSRSHVLRSGAGQQP 2746
                |.::|       |.|        |::..|...:|..::.    :...||.:||      :.
Yeast   531 ----LSLDD-------DHN--------LINMFTPWASTGMRKQ----SAIISRDNVL------ED 566

  Fly  2747 VEHSSSSAGANENA-LNMVIAQQFSDTNSANPAAIDNPSSTTTATTVVQHNTTTNNSSIITTTTT 2810
            ..::.:|.|....| |::....:|.:     .|.||....|               ...:||.:.
Yeast   567 AFNAFNSIGERFKASLDVTFINEFGE-----EAGIDGGGIT---------------KEFLTTVSD 611

  Fly  2811 TSYVHAVHGLFPLPLGKSSKLPQMTKAKAKFK---FLGKFMAKAVMDSRMLDLPFSLPFYRWLVS 2872
            ..:....|.||... .:....|.:.....|.|   ||||.:.|.:.:..::|:.|:..|.:.|::
Yeast   612 EGFKDPKHELFRTN-DRYELYPSVVYDATKLKYIWFLGKVVGKCLYEHVLIDVSFADFFLKKLLN 675

  Fly  2873 EEHSI--GLADLMRVAPEVQNTLVRLQDLVRQREYILSDPNIDAMEKTEKIEQLDLDGCPIADLG 2935
            ..:..  ..:||......:.|.|::|.::.                 |::|:.|||      ...
Yeast   676 YSNGFLSSFSDLGSYDSVLYNNLIKLLNMT-----------------TDEIKSLDL------TFE 717

  Fly  2936 LDFVLPGHANIELCRGGRDTPVTVHNLHQYISLVTYWFLIEGVQKQFEALREGFDSVFPIQRLRM 3000
            :|........::|...|..|.||..|:..|::.||.:.|.:...|...|...|...:.....:.|
Yeast   718 IDEPESSAKVVDLIPNGSKTYVTKDNVLLYVTKVTDYKLNKRCFKPVSAFHGGLSVIIAPHWMEM 782

  Fly  3001 FYPEELECVFCGSGSEQQHSRWEIKMLQESCRTDH-GFHQDSQAIQYLYEILASYNRDEQRAFLQ 3064
            |...||:.:..|       .|..|.:......|:: |:.::.|.|...:|:|..:..:|:..||:
Yeast   783 FNSIELQMLISG-------ERDNIDLDDLKSNTEYGGYKEEDQTIVDFWEVLNEFKFEEKLNFLK 840

  Fly  3065 FVTGSPRLPTGGFKALTPPLTIVRKTLDENQNPNDY-LPSVMTCVNYLKLPDYSSREVMRQKLKV 3128
            |||..|:.|..|||||.|...|      .|.....| ||:..||||.||||||.::.::|:||..
Yeast   841 FVTSVPQAPLQGFKALDPKFGI------RNAGTEKYRLPTASTCVNLLKLPDYRNKTILREKLLY 899

  Fly  3129 AANEGSMSFHLS 3140
            |.|.|: .|.||
Yeast   900 AINSGA-RFDLS 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ctrip	NP_001189170.1	Extensin_2	<688..731	CDD:252669
		WWE	1409..1481	CDD:128922
		FAM199X	<1985..2074	CDD:292442
		HECTc	<2818..3138	CDD:294058	87/326 (27%)
HUL5	NP_011374.1	HUL4	35..910	CDD:227354	133/595 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900