DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ctrip and MAGIX

DIOPT Version :9

Sequence 1:NP_001189170.1 Gene:ctrip / 40596 FlyBaseID:FBgn0260794 Length:3140 Species:Drosophila melanogaster
Sequence 2:NP_079135.3 Gene:MAGIX / 79917 HGNCID:30006 Length:334 Species:Homo sapiens


Alignment Length:298 Identity:62/298 - (20%)
Similarity:94/298 - (31%) Gaps:96/298 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly  1654 QLTDPNNPICANPSPKPL-----SATATPTANAGGSQSAP----ASAN-SLQV----NPFFMDSA 1704
            ::||...|.......:|.     :..|.|....|.::|||    ||.: |:::    ..|.:...
Human    76 EVTDSRLPHATIVDHRPQHRWLETCNAPPQLIQGKARSAPKPSQASGHFSVELVRGYAGFGLTLG 140

  Fly  1705 PGLSSASTTPSSSKHQSYSVKSFSHAMNALTASAKGTPSGALDATS-----SSTTAGGYNYSSSA 1764
            .|...|..||.              |:..|.........|.|:...     :..:..|..::.:.
Human   141 GGRDVAGDTPL--------------AVRGLLKDGPAQRCGRLEVGDLVLHINGESTQGLTHAQAV 191

  Fly  1765 PSSSSGAPAAYFV------TQQGDPRQYVHFQQPAVPAPPPQQELLPSGVQQQGQQVPQVIYQPH 1823
            ....:|.|..:.|      |..|.||.....::..||:.|.:.. .|.|        |:|     
Human   192 ERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSP-DPGG--------PEV----- 242

  Fly  1824 HQQPAHLVLASTSSGAASSSSSSSSSSSASALQHKMTDMLKRKAPPKRKS--QSGGRAKSRQEDA 1886
                                 :.|.|||.|.:||          ||.|.:  ::.|..:...|.|
Human   243 ---------------------TGSRSSSTSLVQH----------PPSRTTLKKTRGSPEPSPEAA 276

  Fly  1887 AVAPAGS-------GPGGAPPSSSGSAM---HELLSRA 1914
            |..|..|       .|....|.|.|..:   .|.||||
Human   277 ADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRA 314

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ctripNP_001189170.1 Extensin_2 <688..731 CDD:252669
WWE 1409..1481 CDD:128922
FAM199X <1985..2074 CDD:292442
HECTc <2818..3138 CDD:294058
MAGIXNP_079135.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..26
PDZ_signaling 124..206 CDD:238492 14/95 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 209..306 31/141 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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