DRSC/TRiP Functional Genomics Resources

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Protein Alignment ctrip and Wwp2

DIOPT Version :9

Sequence 1:NP_001189170.1 Gene:ctrip / 40596 FlyBaseID:FBgn0260794 Length:3140 Species:Drosophila melanogaster
Sequence 2:NP_080106.1 Gene:Wwp2 / 66894 MGIID:1914144 Length:870 Species:Mus musculus


Alignment Length:317 Identity:95/317 - (29%)
Similarity:156/317 - (49%) Gaps:46/317 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly  2826 GKSSKLPQMTKAKA-------KFKFLGKFMAKAVMDSRMLDLPFSLPFYRWLVSEEHSIGLADLM 2883
            ||::...|:..|.:       .|:|:|:|:|.|:...:.:|..|:||||:.::::..:  |.||.
Mouse   583 GKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPT--LKDLE 645

  Fly  2884 RVAPEVQNTLVRLQDLVRQREYILSDPNIDAMEKTEKIEQLDLDGCPIADLGLDFVLPGHANIEL 2948
            .:.||..|::|.:                    |...:|:..|:...|.|:.:...:..|   ||
Mouse   646 SIDPEFYNSIVWI--------------------KENNLEECGLELFFIQDMEILGKVTTH---EL 687

  Fly  2949 CRGGRDTPVTVHNLHQYISLVTYWFLIEGVQKQFEALREGFDSVFPIQRLRMFYPEELECVFCGS 3013
            ..||.:..||..|..:||.|:|.|....||::|.:|..:||:.|.|::.||.|..:|||.:.||.
Mouse   688 KEGGENIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGM 752

  Fly  3014 GSEQQHSRWEIKMLQESCRTDHGFHQDSQAIQYLYEILASYNRDEQRAFLQFVTGSPRLPTGGFK 3078
             .|...|.|     |::....| :.:.|:.||:.::::...:.:::...||||||:.|||.|||.
Mouse   753 -QEIDMSDW-----QKNAIYRH-YTKSSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFA 810

  Fly  3079 AL---TPPLTIVRKTLDENQNPNDYLPSVMTCVNYLKLPDYSSREVMRQKLKVAANE 3132
            .|   ..|    :|...:......:||...||.|.|.||.|.|.|.:::||..|..|
Mouse   811 ELIGSNGP----QKFCIDRVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEE 863

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ctripNP_001189170.1 Extensin_2 <688..731 CDD:252669
WWE 1409..1481 CDD:128922
FAM199X <1985..2074 CDD:292442
HECTc <2818..3138 CDD:294058 95/317 (30%)
Wwp2NP_080106.1 C2_E3_ubiquitin_ligase 17..142 CDD:175988
PRK07003 <149..>299 CDD:235906
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 150..300
WW 302..331 CDD:366073
WW 332..361 CDD:366073
WW 407..435 CDD:366073
WW 447..477 CDD:238122
HECTc 516..868 CDD:238033 95/317 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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