DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ctrip and herc5.1

DIOPT Version :9

Sequence 1:	NP_001189170.1	Gene:	ctrip / 40596	FlyBaseID:	FBgn0260794	Length:	3140	Species:	Drosophila melanogaster
Sequence 2:	XP_017211386.1	Gene:	herc5.1 / 559981	ZFINID:	ZDB-GENE-090311-56	Length:	884	Species:	Danio rerio

Alignment Length:	301	Identity:	72/301 - (23%)
Similarity:	129/301 - (42%)	Gaps:	54/301 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  2833 QMTKAKAKFKFLGKFMAKAVMDSRMLDLPFSLPFYRWLVSEEHSIGLADLMRVAPEVQNTLVRLQ 2897
            ::|..|.|:...|.....|..:|.:::|||.|..::            .|:.:.|.       |:
Zfish   618 KLTVEKKKYFLFGILCGLAFNNSSVVNLPFPLALFK------------KLLNIKPS-------LE 663

  Fly  2898 DLV-------RQREYILSDPNIDAMEKTEKIEQLDLDGCPIADLGLDFVLPGHANIELCRGGRDT 2955
            |.:       |..:|||...| |.:|:              :.|.|..:..| :.::|.....:.
Zfish   664 DFIEFNPVHGRSLQYILEYSN-DVLEE--------------SSLPLTIIWSG-SELDLDPAEPEQ 712

  Fly  2956 PVTVHNLHQYISLVTYWFLIEGVQKQFEALREGFDSVFPIQRLRMFYPEELECVFCGSGSEQQHS 3020
            .:|..|..:::.........:.|::.||..|.||......:.:.||.||||..|..|:    :..
Zfish   713 HITTSNRTKFVDEYVDHIFNQSVKEAFEEFRRGFFRGCEKRLVEMFEPEELRGVLVGN----EEY 773

  Fly  3021 RWEIKMLQESCRTDHGFHQDSQAIQYLYEILASYNRDEQRAFLQFVTGSPRLPTGGFKALTPPLT 3085
            .|.|  |:::...:..|:.|...|...:|:......:|:::||.|:||..|:|..|..|:...:|
Zfish   774 DWNI--LKQNTTYEGVFNADHPVIISFWEVFDDLTPNEKKSFLLFLTGFERVPILGMSAVKMRVT 836

  Fly  3086 IVRKTLDENQNPNDYLPSVMTCVNYLKLPDYSSREVMRQKL 3126
            .:..:.:      |:||..:||.:.|:||.|..||.:|.|:
Zfish   837 HLANSTE------DHLPETLTCHSLLQLPKYEKRETLRAKV 871

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ctrip	NP_001189170.1	Extensin_2	<688..731	CDD:252669
		WWE	1409..1481	CDD:128922
		FAM199X	<1985..2074	CDD:292442
		HECTc	<2818..3138	CDD:294058	72/301 (24%)
herc5.1	XP_017211386.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900