Protein Alignment ctrip and hyd

DIOPT Version :9

• Sequence 1: NP_001189170.1
• Gene: ctrip / 40596
• FlyBaseID: FBgn0260794
• Length: 3140
• Species: Drosophila melanogaster
• Sequence 2: NP_001287262.1
• Gene: hyd / 41181
• FlyBaseID: FBgn0002431
• Length: 2887
• Species: Drosophila melanogaster
• Alignment Length: 2471
• Identity: 445/2471 - (18%)
• Similarity: 796/2471 - (32%)
• Gaps: 802/2471 - (32%)

  Fly   917 PPSGPPHAGGQQITPGANSANLSIVAAALSAARDVGGGSDGGGSAGGATPATGASASSVGNTSAV 981
            ||..|  :||.:        ..|:|  .||.||.:...|.   ||..::.|.||||||....|:.
  Fly   968 PPDSP--SGGVE--------KKSLV--GLSVARSIPTVST---SAYVSSIAFGASASSSNENSSF 1017

  Fly   982 GASSSSNSSAGQAASSNSNNVT--------------ATGSGSAPGG----------GPTSTGTTS 1022
            ...||  |:||.|:|::.:|.|              |..|||.|..          .|..|...|
  Fly  1018 ATMSS--SAAGSASSTSRDNRTNLRDMMNRLINSDQAEQSGSQPMATNNEDHAYIPWPAETPAAS 1080

  Fly  1023 GTQHGSGSGAAAAVD--------SESDDSEVGRLQALLEARGLPPHLFGALGPRVTHILHRTIGN 1079
            .....|....:.:::        |.|..|.:..::.     |.|.:.|. |..|..|.|  ||
  Fly  1081 NLSASSSQNVSDSIEDDISKIIPSSSQSSMLSNIKL-----GSPTYTFD-LAQRREHAL--TI-- 1135

  Fly  1080 SSSSKANQLLQGLQSHDESQQLQAAIEMCQMLVMGNEDTLAGFPIKQVVPALIQLLRMEHNFDIM 1144
                        ||....|..|:.  .:|.||  ..:|.....|.                  ::
  Fly  1136 ------------LQQMCVSPALRP--YLCHML--STKDAQGQTPF------------------ML 1166

  Fly  1145 NNACRALAYMLEALPRSSGTVVEAVPVFLEKLQVIQCMDVAEQSLSALEILSRRHNKAILQANGI 1209
            :.:|||               .||..:.|..:.::     :||.....|        |::..||.
  Fly  1167 SVSCRA---------------YEAGIILLNTILML-----SEQDPQLKE--------AMIFPNGS 1203

  Fly  1210 SA------CLTYLDFFSIVAQRAALAIAANCCLNMHPEEFHFVAESLPLLARLLSQQDKKCIESV 1268
            .|      .:.|.|..|.....|.           |..:..|..::..|...|       |..:.
  Fly  1204 PADQSPLHVICYNDTCSFTWTGAD-----------HINQNIFECKTCGLTGSL-------CCCTE 1250

  Fly  1269 CSAFCRLVESFQHDG-----QRLQQIASPDLLKNCQQLLLVTPAILNTGTFTAVVRMLSLMC--C 1326
            |:..|       |.|     :|....|..|..:.|:...|:      .|..|   :..:|:|  .
  Fly  1251 CARVC-------HKGHDCKLKRTAPTAYCDCWEKCKCKALI------AGNLT---KRFALLCKLV 1299

  Fly  1327 SCPDLAISLLRNDIAATLLYLLTGNAEPAAASATHVELISRSPSELYELTCLIGELMPRLPLDGI 1391
            ||.|| ::...:...:.||:|              ::.:.|...|..:..
  Fly  1300 SCTDL-VTKFNSKGESILLFL--------------IQTVGRQIVEQRQYR--------------- 1334

  Fly  1392 FAVDSLLDRPTLNTQDQVHWQWRDDRGSWHNYSTIDSRLIEAA---NQSSEDEISLSTFGRTYTV 1453
            |:| .:.:..|..|            |:..|.|.|.:|...||   |...:.::....|.|
  Fly  1335 FSV-RVRNVSTAAT------------GATGNNSVISNRKTSAAEIDNDMPDHDLEPPKFAR---- 1382

  Fly  1454 DFHAMQQINEDTGTTRPVQRRLNHNYVAPMSAGQDLTTTSAGSAAAGGASTSAAAAAASSNNNNN 1518
              .|::::..|....|                          |....||........|.|.:.|:
  Fly  1383 --KALERLLIDWNAVR--------------------------SMIMSGAERGDVPNPAGSASENS 1419

  Fly  1519 NNNNPPGNSVNLNQVKRRPSLDARIACLKEERGLAADFIKHIFNVLYEVYSSSAGPNVRYKCLRA 1583
            |:..                                      ||:..:   :..|..:..|...:
  Fly  1420 NSEG--------------------------------------FNMFIQ---TQHGSTLLDKFTHS 1443

  Fly  1584 LLRMVYYATPELLRQVLKYQLVSSHIAGMLGSNDLRIVVGALQMAEILMRQLPDVFGTHFRREGV 1648
            |:                .:..|.|:..:     |..:|..||.|.:..|..        ..|.|
  Fly  1444 LI----------------VKCTSDHLDTL-----LLTLVRELQNASVSNRSK--------EAEEV 1479

  Fly  1649 IYQFTQLTDPNNPICANPSPKPLSATATPTANAGGSQSAPASANSLQVNPFFMDSAPGLSSASTT 1713
            :.:|.:                                  :.|....:  |.::..|......:.
  Fly  1480 VRRFVR----------------------------------SVARVFVI--FNLEKQPNPEKRKSH 1508

  Fly  1714 PSSSKHQSYSVKSFS--HAMN---------ALTASAKGTPSGALDATSSSTTAGGYNYSSSAPSS 1767
            .|.:|:....||.|.  |.::         ||.|..:   .|.:..|:..|       .||:...
  Fly  1509 SSCNKYVQSCVKVFQTLHKISIEELCEVSEALIAPVR---LGVVRPTAPFT-------MSSSNLD 1563

  Fly  1768 SSGAPAAYFVTQQGDPRQYVHFQQPAVPAPPPQQELLPSGVQQQGQQVPQVIYQPHHQQPAHLVL 1832
            ...:...:.|    ||                   |.||.|:...:|:  :::...:.|.|:..:
  Fly  1564 VRNSDDLFSV----DP-------------------LAPSNVESPSEQI--LVHDAGNDQSANFNI 1603

  Fly  1833 ASTSSGAASSSSSSSSSS----SASALQHKMTDMLKRKAPPKRKSQSGGRAKSRQEDAAVAPAGS 1893
            .......|..:...:|.|    :..|..|...|.|..    .::::.|.:......|.....|.:
  Fly  1604 QQNYDVVAMETIRDASESEEVINREANSHNQDDELIE----NQRNEDGMQDDESDNDFTFNDAET 1664

  Fly  1894 GPGGAPPSSSGSAMHELLSRATSLGSGN--GGRSTPNSGGGSGSSKSRFNAGNSSNAGSSKSSFL 1956
             ...:..:.|...:...:....::||.|  |.....:..|.|.:.:...:....|:..|.:.:|
  Fly  1665 -ESDSDDNQSNQEVQRSVQAGATVGSENDIGVLFLEDESGDSSAQEEDGSEDGESDDQSDEFNF- 1727

  Fly  1957 ASLNPARWGRQ-THQNHHHHHQQSQQQHHGLSKDSGNSN-------------------STGSGSG 2001
               |..:..|: |:.|..........|....|:|:..|:                   ||...|.
  Fly  1728 ---NEQQLERRSTNSNARSDLAPQTMQWAIRSRDTARSSVRVPTGSNMVFIDPMALRRSTVPAST 1789

  Fly  2002 AGLAYTVSQHGAGSGAGGLNAA--AVAASISKSISHANLLAAANRERARQWVREQAVDFVKRYTE 2064
            .....::..|...:.|..|..|  .....||:.||..:.....:.|.:.:...::|: .|:.:.|
  Fly  1790 TVTTPSIEPHTMATTASNLARAFGITIRQISELISILSYNVLNDIETSLKIQNDEAI-AVQAFVE 1853

  Fly  2065 QEAKR-----------SKAASESGATQSGSSG-------VGLS---STGNTPL-STAGSTNVLER 2107
            :..|.           ::|..:.||..:..:.       :.||   |:..||. :|:.|.|.:..
  Fly  1854 KRLKATWDWMFTVMDGTEAQLKFGAYLTNYTDPNHPLHPLNLSAQASSSQTPAPATSSSVNGVNI 1918

  Fly  2108 LSS-----------ILFKLNGSYH-DCLDALLELKTILLESDISPFEVNH-SGLIKAMLNYMTSE 2159
            :.|           .|.:.:.|.| |.|..|          ||:  .:.| :.::.|.:.||.::
  Fly  1919 MGSNSRRDFFTYCLSLMRSHTSEHRDALPVL----------DIT--ALRHIAYVLDAFVYYMRND 1971

  Fly  2160 TGLVERDARLRSFMHVFAGLPLEPLLQNVGQMPTIEPIAFGAFVAKLNGCVTQLEQFPVKVH--- 2221
            :|..::...:...::     .|.|:.::   ..|.:.:|             .||:|...|.
  Fly  1972 SGFYDKQDTISGRIN-----NLSPMTES---YDTDDELA-------------NLEEFNADVQMSA 2015

  Fly  2222 -DFPAG-PGGRSNQSALRFFNTHQLKCNLQRHPQCNNLRQWKGGTVKIDPLAMVQAIERYLVVRG 2284
             ..|:| .|.|.:....|..:|..|.|:..           :|..:.:| :||..|.:.:|:
  Fly  2016 SSMPSGSQGTRRHAFFARSESTLSLGCSAP-----------EGFELPLD-MAMPLADKPHLL--- 2065

  Fly  2285 YGGIRADSDDDSEEDMDDNVAAVVLSQASFRHKLQFTIGDHVLPYNMTVYQAVKQFSPLVSEQPE 2349
                   ..:...:::..|:..:|.:.|:.........|..:..|.                 |.
  Fly  2066 -------QPNSKRQELFANLPLLVTTNANNSGATNDGDGGSIFDYT-----------------PT 2106

  Fly  2350 TDNESETLLGNASIWVQQHTIHYRPVEEEVT-SGAAAGAASSSSSCSSGVQ-KQQSSSSSASSCV 2412
            ....|.:|..|..::   .|:   |::...| .|.....|..|:..:..|| |::..|....|..
  Fly  2107 RLGFSNSLKRNERVY---ETV---PIDSSKTGDGNVTNKAEGSTDSNIYVQLKKKQGSDDFKSHK 2165

  Fly  2413 NATSSCSSSSGVA--SGGGSLTKKAHKSSSKFMRKKTELWHEGIAPVVISALKPFLSSSLPA-DV 2474
            .|..:.|....|.  ....||...: ||:...|..:.|        |:|:..|..:|.:..| .|
  Fly  2166 EADGNQSKYEKVVLMETDDSLPSTS-KSTEALMATRPE--------VIIAPNKASVSPATAARSV 2221

  Fly  2475 VTVQDASLDALCMLRVIHALNRH---------------------WDHLYGCVVRQNIIPQSDFIH 2518
            :.:...|    |:..:...:|.:                     .|||.....|.:...||:|
  Fly  2222 IVLAGGS----CLKTIDSDINNYSASNLSTAEQAKCDTQYQKSTSDHLLLFPARGSQFYQSNF-- 2280

  Fly  2519 PKIMAKANRQLQDPLVIMTGNLPQW------------------LPQIGM----ACPFLFPFETRH 2561
                               ..||.|                  :..:||    ..|.|..|..:.
  Fly  2281 -------------------SELPSWNFLLSRWKLTLDLFGRVFMDDVGMEHGSVLPELRGFPVKE 2326

  Fly  2562 LLFYATSFDRDRALQRLLDTTPDLNAAESSERVAPRLDRRKRAISRTEILKQAEHILQDFGHSKA 2626
            :.|       .|.:::|.:       .:..:.|..:|:|.:.::    |::..:.:...||:...
  Fly  2327 MRF-------RRHMEKLRN-------GQQRDLVLCKLERNRESL----IVQTFKELNTQFGNQSR 2373

  Fly  2627 LLE---------IQYENEVGTGLGPTLEFYA------LVSAE---LQRTDLGLWNGSDSYKQNSV 2673
            .::         :.:::|.|.|.|....||.      |.||:   |:...:|     .::.:..|
  Fly  2374 RIQPPITFNRVKVTFKDEPGEGSGVARSFYTSIAEALLASAKIPNLESVQVG-----TNHSKYVV 2433

  Fly  2674 TIVDVVKANSAVLHIEDALEATTTDQNTPAVAGAS---LVSSSTTTTTTTAQQHQHPPTRSSSRS 2735
            ....::::.:        :..::.||:|....|::   |..|:............:.|..||..:
  Fly  2434 PFSSILRSRT--------VSGSSRDQSTLQRRGSNSKILWRSARERKALNLDARPYTPPNSSDNA 2490

  Fly  2736 -----------HVLRSGAGQQPVEHSSSSAGA-----------------------------NENA 2760
                       |:.:.|....|..||.:...|                             || |
  Fly  2491 TPESLNDHLSVHLQQIGERLYPKIHSINQTHAPKITGMLLEIPTPQLLSVISSDETLRQKVNE-A 2554

  Fly  2761 LNMVIAQQFSDTNSANPAAIDNPSSTTTATTVVQHNTTTNNSSIITTTTTTSYVHAVHGLFPLPL 2825
            :.::..:|.|:|::.:.....:||      .||......:|..:.       |.....|.:....
  Fly  2555 IEIITFKQKSETSAQSSQPKKSPS------VVVVDPVDDDNEPLF-------YSPGKRGFYTPRQ 2606

  Fly  2826 GKSSKLPQMTKAKAKFKFLGKFMAKAVMDSRMLDLPFSLPFYRWLVSEEHSIGLADLMRVAPEVQ 2890
            |.:|    ..:..| |:.:|:.:...::.:.:|.|.......::::..:  |...||....|.:.
  Fly  2607 GFAS----FERINA-FRNIGRLIGLCLLQNELLPLFLQRHVLKYILGRK--IKFHDLAFFDPALY 2664

  Fly  2891 NTLVRLQDLVRQREYILSDPNIDAMEKTEKIEQLDLDGCPIADLGLDFVLPGHANIELCRGGRDT 2955
            .:.         |:.|   .|....|..|.|.:::|  |.:.||..:   .|..|.||..||||.
  Fly  2665 ESF---------RQII---QNAQTKEGEETINRMEL--CFVIDLMKE---EGCGNRELIPGGRDV 2712

  Fly  2956 PVTVHNLHQYISLVTYWFLIEGVQKQFEALREGFDSVFPIQRLRMFYPEELECVFCGSGS----- 3015
            .||..|:.:|:...|.:.||:..:|..|||::|...|.|...:.....|:|..:..|.|.
  Fly  2713 AVTSSNIFEYVRRYTEYRLIKSQEKALEALKDGVFDVLPDNSMINLTAEDLRLLLNGVGDINVST 2777

  Fly  3016 -------EQQHSRWEIKMLQESCRTDHGFHQDSQAIQYLYEILASYNRDEQRAFLQFVTGSPRLP 3073
                   ..:.|....|:|:..              ::.:.|:...|..|::..:.|.||||.||
  Fly  2778 LISYTTFNDESSEGPDKLLKFK--------------KWFWSIVEKMNIMERQDLVYFWTGSPALP 2828

  Fly  3074 TG--GFKALTPPLTIVRKTLDENQNPNDYLPSVMTCVNYLKLPDYSSREVMRQKLKVAANEGSMS 3136
            ..  ||:.| |.:||  :..|::     :||:..||::.|.:|.|||:.::|.|:.:|....:..
  Fly  2829 ASEEGFQPL-PSVTI--RPADDS-----HLPTANTCISRLYIPLYSSKSILRSKMLMAIKSKNFG 2885

  Fly  3137 F 3137
            |
  Fly  2886 F 2886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ctrip	NP_001189170.1	Extensin_2	<688..731	CDD:252669
		WWE	1409..1481	CDD:128922	13/74 (18%)
		FAM199X	<1985..2074	CDD:292442	20/120 (17%)
		HECTc	<2818..3138	CDD:294058	81/334 (24%)
hyd	NP_001287262.1	E3_UbLigase_EDD	150..196	CDD:288409
		ZnF_UBR1	1217..1284	CDD:197698	16/91 (18%)
		ASF1_hist_chap	1535..1733	CDD:304562	39/241 (16%)
		PolyA	2498..2561	CDD:197769	9/63 (14%)
		HECTc	2589..2885	CDD:238033	82/348 (24%)
		HECTc	2589..2884	CDD:214523	82/347 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900