DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ctrip and yki

DIOPT Version :9

Sequence 1:	NP_001189170.1	Gene:	ctrip / 40596	FlyBaseID:	FBgn0260794	Length:	3140	Species:	Drosophila melanogaster
Sequence 2:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	341	Identity:	79/341 - (23%)
Similarity:	116/341 - (34%)	Gaps:	100/341 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   565 SSNSNS----------------SNNVV-------DYSIMPHLTTVATTTPHALTPQQHQQQRQPP 606
            |||:||                |||:|       |.::.....:|       |.|   ...::|.
  Fly    31 SSNTNSLIEKEIDDEDMLSPIKSNNLVVRVNQDTDDNLQALFDSV-------LNP---GDAKRPL 85

  Fly   607 QPPSHQQQQVHQQQQPPQLLPTHQFAHLSSFVTPTAAAAAAAAAAHYPPASAAAAYFAQQQH--- 668
            |.|...::           ||       :||.||       .|.:|....||.:.|.|..|.
  Fly    86 QLPLRMRK-----------LP-------NSFFTP-------PAPSHSRANSADSTYDAGSQSSIN 125

  Fly   669 --------HQHQHQHQQQHVQQAQAPQPHYYHSSVAVLHQPPPHHFTSTGAGPPPALFQQQAPPQ 725
                    .|...|.....:.|.|. ||...||.:|:      ||   :.|...||..||..  .
  Fly   126 IGNKASIVQQPDGQSPIAAIPQLQI-QPSPQHSRLAI------HH---SRARSSPASLQQNY--N 178

  Fly   726 LTRYTPATATTAATFVPPQQQQVV-----YNPQQQQHSSLRRSSR---GKTGSCVSSAAAAQQQQ 782
            :...:.|.|.......|..|||..     .|..|:..|....||.   ....:|:|.......|.
  Fly   179 VRARSDAAAANNPNANPSSQQQPAGPTFPENSAQEFPSGAPASSAIDLDAMNTCMSQDIPMSMQT 243

  Fly   783 HHQQQQHSSAAAAVQ--QQL-LPPPGTYQYQQVGGNTVVVAVRHQQQLQQ------QQQQQQQLA 838
            .|::|:.....:.:|  :|| ..|||..|.:...|.  :..:.|..:..|      |.:||||:.
  Fly   244 VHKKQRSYDVISPIQLNRQLGALPPGWEQAKTNDGQ--IYYLNHTTKSTQWEDPRIQYRQQQQIL 306

  Fly   839 LHHQHQQQQHQQQQQQ 854
            :..:.:|....|..:|
  Fly   307 MAERIKQNDVLQTTKQ 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ctrip	NP_001189170.1	Extensin_2	<688..731	CDD:252669	11/42 (26%)
		WWE	1409..1481	CDD:128922
		FAM199X	<1985..2074	CDD:292442
		HECTc	<2818..3138	CDD:294058
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	17/64 (27%)
		WW	266..295	CDD:395320	7/30 (23%)
		WW	335..364	CDD:395320
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900