DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ctrip and Herc6

DIOPT Version :9

Sequence 1:	NP_001189170.1	Gene:	ctrip / 40596	FlyBaseID:	FBgn0260794	Length:	3140	Species:	Drosophila melanogaster
Sequence 2:	XP_008761185.1	Gene:	Herc6 / 362376	RGDID:	1561739	Length:	1027	Species:	Rattus norvegicus

Alignment Length:	301	Identity:	70/301 - (23%)
Similarity:	122/301 - (40%)	Gaps:	54/301 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  2838 KAKFKFLGKFMAKAVMDSRMLDLPFSLPFYRWLVSEEHSIGLADLMRVAPEVQNTLVRLQDLVRQ 2902
            |:::...|.....::.:..:::|.|.|..|:.|:.::.|                |..|:||
  Rat   765 KSRYFLFGILCGLSLNNLNVINLSFPLALYKKLLEQKPS----------------LEDLKDL--- 810

  Fly  2903 REYILSDPNIDAMEKTEKIEQLDLDGCPIADLGLDF-VLPGHANIELCRGGRDTPVTVHNLHQYI 2966
              .:|...|:.        |.|:.:...|.:|.:.| :.....:::|...|...||...|...|:
  Rat   811 --SLLLGRNLQ--------EVLNCEAGVIEELHMYFSIYWDQRDVDLIPDGISVPVNETNKRDYV 865

  Fly  2967 S-LVTYWFLIEGVQKQFEALREGFDSVFPIQRLRMFYPEELECVFCGSGSEQQHSRWEIKMLQES 3030
            | .|.|.|.| .::..::....||..|.....:|.|.||||.....|:.:    ..|  |..:.:
  Rat   866 SKCVDYIFNI-SIKTIYDEFHRGFYKVCNRDSIRHFQPEELMAAIIGNPT----CDW--KQFENN 923

  Fly  3031 CRTDHGFHQDSQAIQYLYEILASYNRDEQRAFLQFVTGSPR-----LPTGGFKALTPPLTIVRKT 3090
            .:.::|:.:....|...::.......||::.||.|:||..|     |...|.:...|      :.
  Rat   924 SKYENGYSKSHPTILLFWKAFHELTLDEKKKFLLFLTGCDRLHVKGLQNEGIRFRCP------EV 982

  Fly  3091 LDENQNPNDYLPSVMTCVNYLKLPDYSSREVMRQKLKVAAN 3131
            ..|..||..     :||.:.|.||.||:...|::.|:||.|
  Rat   983 FSERDNPRS-----LTCHSILDLPKYSTMRRMKEALQVAIN 1018

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ctrip	NP_001189170.1	Extensin_2	<688..731	CDD:252669
		WWE	1409..1481	CDD:128922
		FAM199X	<1985..2074	CDD:292442
		HECTc	<2818..3138	CDD:294058	70/301 (23%)
Herc6	XP_008761185.1	RCC1	39..88	CDD:278826
		RCC1	92..141	CDD:278826
		RCC1	144..194	CDD:278826
		RCC1_2	182..210	CDD:290274
		RCC1_2	236..265	CDD:290274
		RCC1	252..299	CDD:278826
		HECTc	682..1023	CDD:238033	70/301 (23%)
		HECTc	706..1023	CDD:214523	70/301 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900