Protein Alignment ctrip and Hace1

DIOPT Version :9

• Sequence 1: NP_001189170.1
• Gene: ctrip / 40596
• FlyBaseID: FBgn0260794
• Length: 3140
• Species: Drosophila melanogaster
• Sequence 2: XP_006256657.1
• Gene: Hace1 / 361866
• RGDID: 1306114
• Length: 916
• Species: Rattus norvegicus
• Alignment Length: 1116
• Identity: 228/1116 - (20%)
• Similarity: 379/1116 - (33%)
• Gaps: 366/1116 - (32%)

  Fly  2139 SPFEVNHS-GLIKAMLNYMTSETGLVERDARLRSFMHVFAGLPLEPLLQNVGQMPTIEPIAFGA- 2201
            |.|:||:: |.:|..|.::.:..|.||                ...||...|..|..:.|: |.
  Rat    53 SKFDVNYAFGRVKRSLLHIAANCGSVE----------------CLVLLLKKGANPNYQDIS-GCT 100

  Fly  2202 --FVAKLNG---CVTQLEQFPVKVHDFPAGPGGRSNQSALRFFNTHQLKCNLQRHPQCNNLRQWK 2261
              .:|..||   |:::|.::...|                          |:     |||    :
  Rat   101 PLHLAARNGQKKCMSKLLEYSADV--------------------------NI-----CNN----E 130

  Fly  2262 GGTVKIDPLAMVQAIERYLVVRGYGGIRAD-----SDDDSEEDMDD------------------- 2302
            |.|          || .:|.|.|...:..|     :|.|.|:.|..
  Rat   131 GLT----------AI-HWLAVNGRTELLHDLVQHVTDVDVEDAMGQTALHVACQNGHKTTVQCLL 184

  Fly  2303 ---------NVAAVVLSQASFRHKLQFTI------GDHVLP---------------YNMTVYQAV 2337
                     |||.......:..|..:.|.      |...||               |..|. :.:
  Rat   185 DSGADINRPNVAGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGQTC-EVL 248

  Fly  2338 KQFSPLVSEQPETDNESETLLGNASIWVQQHTIHYRPVEE-EVTSGAAAGAASSSSSCSSGVQKQ 2401
            .|:.|.:.:......::|.|..|....|.||.......:. ::.:|.|..|.::.....|..:..
  Rat   249 IQYHPRLFQTIVQMTQNEDLRENMLRQVLQHLSQQSESQYLKILTGLAEVATTNGHKLLSVFRLV 313

  Fly  2402 QSSSSSASS------------C-VNATSSCSSSSGVASG-GGSLTKKAHKSSSKFMRKKTELWHE 2452
            .|.|||..:            | |......|.|:|:..| .|:.|.:     |:..:....|||.
  Rat   314 SSLSSSYEAQMKSLLRIVRIFCHVFRIGPSSPSNGMDMGYNGNKTPR-----SQVFKPLELLWHS 373

  Fly  2453 GIAPVVISALKPFLSSSLPADVVTV------QDASLDALCMLRVIHALNRHWDHLYGCVVRQNII 2511
            ....:|:.|.:...:....||:.::      ||.  :|.|    |.|......   |...|.:..
  Rat   374 LDEWLVLIATELMKNKEDSADITSILLKQKGQDQ--EASC----ISAFEPPGP---GSYERLSTG 429

  Fly  2512 PQSDFIHPKIMA---KANRQLQDPLVIMTGNLPQWLPQIGMAC----------PFLFPFETRHLL 2563
            |...  .|.::|   :|:...||.:.:....|...:....|.|          |....|..:|
  Rat   430 PGES--KPDVLAGKQEASADCQDVISVTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKH-- 490

  Fly  2564 FYATSFDRDRALQRLLDTTPDLNAAESSERVAPRLDRRKRAISRTEILKQAEHIL--QDFGHSKA 2626
                    |..|:..::..|.:           ..|.....:...|::.:..||:  |.|   |.
  Rat   491 --------DEVLKCFVNRNPKI-----------IFDHFHFLLECPELMSRFMHIIKAQPF---KD 533

  Fly  2627 LLEIQYENEVGTGLGPTLEFYALVSAELQRTDLGLWNGSDSYKQNSVTIVDVVKANSAVLHIEDA 2691
            ..|..||: :.:| .|..:   :|...:...|:.|.: .||..::|..||.  |||.|.|....|
  Rat   534 RCEWFYEH-LHSG-QPDSD---MVHRPVSENDILLVH-RDSIFRSSCEIVS--KANCAKLKQGIA 590

  Fly  2692 LEATTTDQNTPAVAGASLVSSSTTTTTTTAQQHQHPPTRSSSRSHVLRSGAGQQPVEHSSSSAGA 2756
            :                                         |.|
  Rat   591 V-----------------------------------------RFH-------------------- 594

  Fly  2757 NENALNMVIAQQFSDTNS---ANPAAIDNPSSTTTAT-TVVQHNTTTNNSSIITTTTTTSYVHAV 2817
            .|..:...:.:::.|..|   .||   |....|.:|. |..|.|             :.|||:..
  Rat   595 GEEGMGQGVVREWFDILSNEIVNP---DYALFTQSADGTTFQPN-------------SNSYVNPD 643

  Fly  2818 HGLFPLPLGKSSKLPQMTKAKAKFKFLGKFMAKAVMDSRMLDLPFSLPFYRWLVSEEHSIGL--- 2879
            |..:                   |:|.|:.:..|:...:::::.|:..||:      |.:|:
  Rat   644 HLNY-------------------FRFAGQILGLALNHRQLVNIYFTRSFYK------HILGIPVN 683

  Fly  2880 -ADLMRVAPEVQNTLVRLQDLVRQREYILSDPNIDAMEKTEKIEQLDLDGCPIADLGLDF----- 2938
             .|:..:.||....|          ::||.:                    .|:||||:.
  Rat   684 YQDVASIDPEYAKNL----------QWILDN--------------------DISDLGLELTFSVE 718

  Fly  2939 --VLPGHANIELCRGGRDTPVTVHNLHQYISLVTYWFLIEGVQKQFEALREGFDSVFPIQRLRMF 3001
              |......:.|..||....||.:|..:|:.|||...:...:|.|..|..:||....|...:::|
  Rat   719 TDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLF 783

  Fly  3002 YPEELECVFCGSGSEQQHSRWEIKMLQESCRTDH--GFHQDSQAIQYLYEILASYNRDEQRAFLQ 3064
            ...|||.:..|. .|...:.| ||      .|::  |:.::...||:.:|::....::|:...||
  Rat   784 DEYELELLLSGM-PEIDVNDW-IK------NTEYTSGYEREDPVIQWFWEVVEDMTQEERVLLLQ 840

  Fly  3065 FVTGSPRLPTGGFKALTPPLTIVRKTLDENQNPNDYLPSVMTCVNYLKLPDYSSREVMRQKLKVA 3129
            |||||.|:|.|||..:.....:...|:.......:.||:..||:|.||||:|.|:|:::.:|.||
  Rat   841 FVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVA 905

  Fly  3130 ANEGSMSFHLS 3140
            .:.||..:.::
  Rat   906 LHCGSYGYTMA 916

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ctrip	NP_001189170.1	Extensin_2	<688..731	CDD:252669
		WWE	1409..1481	CDD:128922
		FAM199X	<1985..2074	CDD:292442
		HECTc	<2818..3138	CDD:294058	83/332 (25%)
Hace1	XP_006256657.1	ANK repeat	66..95	CDD:293786	8/44 (18%)
		ANK	66..93	CDD:197603	8/42 (19%)
		Ank_2	69..194	CDD:289560	31/187 (17%)
		ANK	92..217	CDD:238125	29/171 (17%)
		ANK repeat	97..128	CDD:293786	8/62 (13%)
		ANK repeat	130..161	CDD:293786	10/41 (24%)
		Ank_2	135..222	CDD:289560	15/87 (17%)
		ANK repeat	163..194	CDD:293786	1/30 (3%)
		ANK repeat	196..221	CDD:293786	3/24 (13%)
		Ank_4	199..249	CDD:290365	7/50 (14%)
		HECTc	561..910	CDD:238033	109/491 (22%)
		HECTc	586..909	CDD:214523	98/462 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900