DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ctrip and Bag3

DIOPT Version :9

Sequence 1:	NP_001189170.1	Gene:	ctrip / 40596	FlyBaseID:	FBgn0260794	Length:	3140	Species:	Drosophila melanogaster
Sequence 2:	NP_001011936.1	Gene:	Bag3 / 293524	RGDID:	1307794	Length:	574	Species:	Rattus norvegicus

Alignment Length:	472	Identity:	100/472 - (21%)
Similarity:	143/472 - (30%)	Gaps:	163/472 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   603 RQPPQPPSHQQQQVH-QQQQPPQLLPTHQFAHLSSFVTPTAAAAAAAAAAH--YPPASAAAAYFA 664
            |.||:.|.......: ..:...:|||                    |...|  ||  .....|..
  Rat    55 RVPPEGPKETASSANGPSRDGSRLLP--------------------AREGHPIYP--QLRPGYIP 97

  Fly   665 QQQHHQHQHQHQQQHVQQAQAPQPHYYHSSVAVLHQPPPHHFTSTGAGPPPALFQQQAPPQLTRY 729
            ...||:.....           |||.:|:    ..||....|.:..|...|   |:...|.....
  Rat    98 IPVHHEGSENR-----------QPHLFHA----YSQPGVQRFRTEAAAAAP---QRSQSPLRGGV 144

  Fly   730 TPATAT--------TAATFVPPQQQQVVYNPQQQQHSSLRRSSRGKTGSCVSSAAAAQQQQHHQQ 786
            |..|.|        .|||..||    ..:.|:        ||.......|.||:::|...
  Rat   145 TETTQTDKQCGQVPAAATAQPP----TAHGPE--------RSQSPAASDCSSSSSSASLP----- 192

  Fly   787 QQHSSAAAAVQQQLLPPPGTYQYQQVGGNTVVVAVRHQQQLQQQQQQQQQLALHHQHQQQQHQQQ 851
               ||..:::....||           ...:.:.|.|:|.:.:...|..    .||.|:..:..|
  Rat   193 ---SSGRSSLGSHQLP-----------RGYIPIPVIHEQNITRPAAQPS----FHQAQKTHYPAQ 239

  Fly   852 QQQHQQQQ---HQQQ--------QRAT--LVQPGFLFSYRSNQPQQQQQPAQ-----QIH----- 893
            |.::|.||   |:.|        .|||  ...|....|.|...|.:...|..     ::|
  Rat   240 QGEYQPQQPVYHKIQGDDWEPRPLRATSPFRSPVRGASSREGSPARSGTPVHCPSPIRVHTVVDR 304

  Fly   894 -------QGPKVTHSSAASDALTYSLMAQQPPSGPPHAGGQQITPG----------ANSANLS-- 939
                   :.|.||             ..:..|...|...|..:.||          |:|..:|
  Rat   305 PQPMTHREPPPVT-------------QPENKPESKPGLAGPDLPPGHIPIQVIRREADSKPVSQK 356

  Fly   940 ------IVAAALSAARDVGGGSDGGGSAGGATPATGASASSVGNTSAVGASSSSNSSAGQAASSN 998
                  .|...:|:| .:...|.|        ||..|..||..|.:|...::.|.:.| :|||..
  Rat   357 PPPPAEKVEVKVSSA-PIPCPSPG--------PAPSAVPSSPKNVAAEPKAAPSPAPA-EAASLK 411

  Fly   999 SNNVTATGSGSAPGGGP 1015
            |      |...||...|
  Rat   412 S------GDAEAPHKHP 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ctrip	NP_001189170.1	Extensin_2	<688..731	CDD:252669	10/42 (24%)
		WWE	1409..1481	CDD:128922
		FAM199X	<1985..2074	CDD:292442
		HECTc	<2818..3138	CDD:294058
Bag3	NP_001011936.1	WW	23..55	CDD:197736	100/472 (21%)
Bag3	NP_001011936.1	BAG	423..500	CDD:214591	100/472 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900