DRSC/TRiP Functional Genomics Resources

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Protein Alignment ctrip and WWP2

DIOPT Version :9

Sequence 1:NP_001189170.1 Gene:ctrip / 40596 FlyBaseID:FBgn0260794 Length:3140 Species:Drosophila melanogaster
Sequence 2:NP_001257383.1 Gene:WWP2 / 11060 HGNCID:16804 Length:870 Species:Homo sapiens


Alignment Length:318 Identity:98/318 - (30%)
Similarity:156/318 - (49%) Gaps:48/318 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly  2826 GKSSKLPQMTKAKA-------KFKFLGKFMAKAVMDSRMLDLPFSLPFYRWLVSEEHSIGLADLM 2883
            ||::...|:..|.:       .|:|:|:|:|.|:...:.:|..|:||||:.::::..:  |.||.
Human   583 GKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPT--LKDLE 645

  Fly  2884 RVAPEVQNTLVRLQDLVRQREYILSDPNIDAMEKTEKIEQLDLDGCPIADLGLDFVLPGHANIEL 2948
            .:.||..|::|.:                    |...:|:..|:...|.|:.:...:..|   ||
Human   646 SIDPEFYNSIVWI--------------------KENNLEECGLELYFIQDMEILGKVTTH---EL 687

  Fly  2949 CRGGRDTPVTVHNLHQYISLVTYWFLIEGVQKQFEALREGFDSVFPIQRLRMFYPEELECVFCGS 3013
            ..||....||..|..:||.|:|.|....||::|.:|..:||:.|.|::.||.|..:|||.:.||.
Human   688 KEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGM 752

  Fly  3014 GSEQQHSRWEIKMLQESCRTDHGFHQDSQAIQYLYEILASYNRDEQRAFLQFVTGSPRLPTGGFK 3078
             .|...|.|     |:|....| :.::|:.||:.::::...:.:::...||||||:.|||.|||.
Human   753 -QEIDMSDW-----QKSTIYRH-YTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFA 810

  Fly  3079 ALT----PPLTIVRKTLDENQNPNDYLPSVMTCVNYLKLPDYSSREVMRQKLKVAANE 3132
            .|.    |....:.|...|.     :||...||.|.|.||.|.|.|.:|:||..|..|
Human   811 ELIGSNGPQKFCIDKVGKET-----WLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEE 863

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ctripNP_001189170.1 Extensin_2 <688..731 CDD:252669
WWE 1409..1481 CDD:128922
FAM199X <1985..2074 CDD:292442
HECTc <2818..3138 CDD:294058 98/318 (31%)
WWP2NP_001257383.1 C2_E3_ubiquitin_ligase 17..142 CDD:175988
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 151..299
Atrophin-1 <164..343 CDD:331285
WW 302..331 CDD:306827
WW 332..361 CDD:306827
WW 407..435 CDD:306827
WW 447..477 CDD:238122
HECTc 516..868 CDD:238033 98/318 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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