DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14655 and STP4

DIOPT Version :9

Sequence 1:	NP_649494.1	Gene:	CG14655 / 40594	FlyBaseID:	FBgn0037275	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_010235.1	Gene:	STP4 / 851512	SGDID:	S000002206	Length:	490	Species:	Saccharomyces cerevisiae

Alignment Length:	332	Identity:	69/332 - (20%)
Similarity:	106/332 - (31%)	Gaps:	89/332 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 TIH--------LFSHTSLMAQEGNESPANGQP------------ASSRGFLAAAPPKRRAKRTRS 96
            |||        |.|.|:..::....|..|..|            :|:...:.::|....|....|
Yeast    45 TIHHLIDPSLPLLSSTTSSSRSTLSSTLNSPPPPPLTTSYSSYNSSACQSITSSPTDNTALAHNS 109

  Fly    97 KPVVP---TPPPVRTTPPAHCDICEF-SFRNTELRDMHVRLVHENAEGEPKQKEPQQKEP----- 152
            |...|   :|.|:.:...:|..:... ||.|.      :.:......|...........|
Yeast   110 KCYFPHSLSPTPLSSNSSSHVILPPISSFTNL------ITVAEREFNGRSNSLHANFTSPVPRTV 168

  Fly   153 -DQEPYKCHLCSKTFRMKGSLRIHLKVVHMMGVPCSNPNPNPNPSPTPASTTSAVTATPKLSICD 216
             |...::...|                             |||      :||...|.||.    .
Yeast   169 LDHHRHELTFC-----------------------------NPN------NTTGFKTITPS----P 194

  Fly   217 RIRHTE--PGALGNGNNSTCTASQPYALSGALSML-----QQSPSSPESGTATPKLWECDVCSKS 274
            ..:|..  |.|:.|...|...:|.|  :||...::     ||..:|..|.:|.|.:.  ...:..
Yeast   195 PTQHQSILPTAVDNVPRSKSVSSLP--VSGFPPLIVKQQQQQQLNSSSSASALPSIH--SPLTNE 255

  Fly   275 FTTKY--FLKKHKRLHTGEMPYTCEICARTFTFQQSYHKHLLYHSEVKPHVCGVCGRAFKELSTL 337
            .|::|  .||...::........|.|| ..|....|.||......|.:||.|.:|.|.|...:.|
Yeast   256 HTSRYSSSLKDSAKITKQRKKKECPIC-HNFYANLSTHKSTHLTPEDRPHKCPICQRGFARNNDL 319

  Fly   338 HNHQRIH 344
            ..|::.|
Yeast   320 IRHKKRH 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14655	NP_649494.1	C2H2 Zn finger	268..288	CDD:275368	4/21 (19%)
		zf-H2C2_2	281..304	CDD:290200	5/22 (23%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		zf-H2C2_2	339..361	CDD:290200	2/6 (33%)
		C2H2 Zn finger	352..372	CDD:275368
		zf-H2C2_2	364..389	CDD:290200
		C2H2 Zn finger	380..396	CDD:275368
STP4	NP_010235.1	COG5048	14..442	CDD:227381	69/332 (21%)
		C2H2 Zn finger	279..296	CDD:275368	7/17 (41%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100