DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14655 and STP3

DIOPT Version :9

Sequence 1:	NP_649494.1	Gene:	CG14655 / 40594	FlyBaseID:	FBgn0037275	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_013479.3	Gene:	STP3 / 851089	SGDID:	S000004367	Length:	343	Species:	Saccharomyces cerevisiae

Alignment Length:	396	Identity:	85/396 - (21%)
Similarity:	122/396 - (30%)	Gaps:	122/396 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VPSFGSIDALQQRLIKAA----NGPLA-------CPFANCK----ELFLGLDKLTIHLFSHTSLM 62
            :|...|.|    .|||||    ||..:       .|..|..    ........|:..|..|::.:
Yeast    14 LPPISSFD----NLIKAAERQYNGEASSASTHPTLPNMNISNGSGSAGASSSMLSYQLLPHSNDV 74

  Fly    63 AQEGNES---PANGQPASSRGFLAAAPPKRRAKRTRS-KPV-------------VPTPPPVRTTP 110
            ::..:.|   |:..||  :.|..:|:.....|..:|| .|:             |.||...:...
Yeast    75 SRSNSSSSFLPSVQQP--TEGSASASETSSSASPSRSISPILKVAGPSSVGGAGVSTPHSTKINK 137

  Fly   111 P---AHCDICEFSFRNTELRDMHVRLVHENAEGEPKQKEPQQKEPDQEPYKCHLCSKTFRMKGSL 172
            |   ..|.||         |:.:..|....|         ....|:..|:||.:|.:.|.....|
Yeast   138 PRKKKQCPIC---------RNFYANLTTHKA---------THLTPEDRPHKCPICHRGFARNNDL 184

  Fly   173 RIHLK------VVHMMGVPCSNPNPNPNPSPTPASTTSAVTATPKLSICD----RIRHTEPGALG 227
            ..|.|      ::...|| .||.|.....|.:|....:....||..|:.|    :..|...|...
Yeast   185 LRHKKRHWKDEILSQSGV-LSNHNDGKGGSVSPNDDDTHEKMTPMNSVTDYAQLKSLHQIKGTFK 248

  Fly   228 NGNNSTCTA----SQPYALSGALSMLQQSPSSPESGTATPKLWECDVCSKS--FTTKYFLKKH-K 285
            ...|||...    ..||.|.                   |..:|...|.::  |:.....|.| |
Yeast   249 CPFNSTLIQLDMDMYPYKLK-------------------PLNFETSNCHQTGVFSRCDTFKNHLK 294

  Fly   286 RLHTGEMPYTCEICARTFTFQQSYHKHLLYHSEVKPHVCGVCGRAFKELSTLHNHQRIHSGEKPF 350
            .||              |.:.....|.   ...|.|..|..||..|:.:....|.   |.|::
Yeast   295 ALH--------------FEYPPGTKKK---DRNVVPGRCKHCGLKFENVDVWLNE---HVGKQ-- 337

  Fly   351 KCEVCG 356
                ||
Yeast   338 ----CG 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14655	NP_649494.1	C2H2 Zn finger	268..288	CDD:275368	5/22 (23%)
		zf-H2C2_2	281..304	CDD:290200	5/23 (22%)
		C2H2 Zn finger	324..344	CDD:275368	5/19 (26%)
		zf-H2C2_2	339..361	CDD:290200	5/18 (28%)
		C2H2 Zn finger	352..372	CDD:275368	2/5 (40%)
		zf-H2C2_2	364..389	CDD:290200
		C2H2 Zn finger	380..396	CDD:275368
STP3	NP_013479.3	COG5048	<137..295	CDD:227381	41/195 (21%)
		C2H2 Zn finger	144..161	CDD:275368	6/34 (18%)
		C2H2 Zn finger	171..191	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100