DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14655 and hkb

DIOPT Version :9

Sequence 1:	NP_649494.1	Gene:	CG14655 / 40594	FlyBaseID:	FBgn0037275	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_524221.1	Gene:	hkb / 40549	FlyBaseID:	FBgn0261434	Length:	297	Species:	Drosophila melanogaster

Alignment Length:	230	Identity:	57/230 - (24%)
Similarity:	90/230 - (39%)	Gaps:	62/230 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 PCSNPNPNP---NPSPTPASTTSAVTAT--------PKLSICDRIRHTEPGALGNGNNSTCTASQ 238
            |..:..|:|   :|..:|..|.:|.||:        |.||....:.:....|      :...||.
  Fly    93 PLLDAAPHPVFSHPQSSPLDTHAAATASLAPPNQHAPFLSAASDLYYAAAAA------AAAAAST 151

  Fly   239 PYALSG------ALSMLQQSPS----------SPESGTATPKLWECDVCSKSFTTKYFLKKHKRL 287
            |.|:.|      .:.:::|..:          :..|....||.::|..|..:|:....||.|.|:
  Fly   152 PTAVPGFGMDPFTMGLMEQEYARVMAEDAQLKALNSRKQRPKKFKCPNCDVAFSNNGQLKGHIRI 216

  Fly   288 HTGEMPYTCEICARTFTFQQSYHKHLLYHSEVKPHVCGVCGRAFKELSTLHNHQRIHSGEKPFKC 352
            ||||.|:.|::                          ..||:.|.....|..|:|||:|.:|:.|
  Fly   217 HTGERPFKCDV--------------------------NTCGKTFTRNEELTRHKRIHTGLRPYPC 255

  Fly   353 EVCGKCFRQRVSFLVHTRIHTGVMPYKCELCQKTF 387
            ..|||.|.:|.....|.:.|   ||.:.:|....|
  Fly   256 SACGKKFGRRDHLKKHMKTH---MPQERQLGPSIF 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14655	NP_649494.1	C2H2 Zn finger	268..288	CDD:275368	7/19 (37%)
		zf-H2C2_2	281..304	CDD:290200	10/22 (45%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		zf-H2C2_2	339..361	CDD:290200	11/21 (52%)
		C2H2 Zn finger	352..372	CDD:275368	7/19 (37%)
		zf-H2C2_2	364..389	CDD:290200	6/24 (25%)
		C2H2 Zn finger	380..396	CDD:275368	2/8 (25%)
hkb	NP_524221.1	COG5048	195..>261	CDD:227381	26/91 (29%)
		zf-C2H2	195..217	CDD:278523	7/21 (33%)
		C2H2 Zn finger	197..217	CDD:275368	7/19 (37%)
		zf-H2C2_2	210..236	CDD:290200	13/51 (25%)
		C2H2 Zn finger	225..247	CDD:275368	7/47 (15%)
		zf-H2C2_2	239..264	CDD:290200	12/24 (50%)
		C2H2 Zn finger	255..275	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050