DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14655 and Bcl6b

DIOPT Version :9

Sequence 1:	NP_649494.1	Gene:	CG14655 / 40594	FlyBaseID:	FBgn0037275	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001101749.1	Gene:	Bcl6b / 360551	RGDID:	1563179	Length:	472	Species:	Rattus norvegicus

Alignment Length:	345	Identity:	96/345 - (27%)
Similarity:	140/345 - (40%)	Gaps:	68/345 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 LAAAPPKRRAKRTRSKPVVPTPPPVRTT-----PPAHCDICEFSFRNTELRDMHVRLVHENAEGE 141
            :.|.||:        .|.||.|...|.:     ||.....|                    ::|.
  Rat   145 MEAEPPR--------PPTVPPPGSPRRSEGHPDPPTESRSC--------------------SQGS 181

  Fly   142 PKQKEPQQKEPDQEPYKCHLCSKTFRMKGSLRIHLKVVHMMGVPCSNPN-PNPNPSPTPASTTSA 205
            |....|..|..:.:.||..:.:......|||     .....|.||.... |:.:.:.:.:|::|:
  Rat   182 PSPASPDPKACNWKKYKFIVLNSQSSQAGSL-----AGESSGQPCPQARLPSGDEACSSSSSSSS 241

  Fly   206 VT-ATP----KLSICDRIRHTEPGALGNGN------------------NSTCTASQP-YALSGAL 246
            .. |||    :||:.......:.|||.|.:                  .|.|.:.|. .|::|..
  Rat   242 EEGATPGLQSRLSLATTTARFKCGALANNSYLFTPPAQETSKQAHPPPGSECLSCQNCEAVAGCS 306

  Fly   247 SMLQQSPSSPESGTATPKLWECDVCSKSFTTKYFLKKHKRLHTGEMPYTCEICARTFTFQQSYHK 311
            |.::  |.:|..   ..|.::|.:|..:|..|..|..|:.:||||.||.|.:|...|....:...
  Rat   307 SGIE--PLAPGD---EDKPYKCQLCRSAFRYKGNLASHRTVHTGEKPYRCSVCGARFNRPANLKT 366

  Fly   312 HLLYHSEVKPHVCGVCGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSFLVHTRIHTGVM 376
            |...||..||:.|..||..|.:::.|..|..||:||||:.|..||..||...:...|.|||||..
  Rat   367 HSRIHSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVRIHTGEK 431

  Fly   377 PYKCELCQKTFRYKVSQRTH 396
            ||.|:.|...||:|...|.|
  Rat   432 PYHCDPCGLHFRHKSQLRLH 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14655	NP_649494.1	C2H2 Zn finger	268..288	CDD:275368	6/19 (32%)
		zf-H2C2_2	281..304	CDD:290200	10/22 (45%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		zf-H2C2_2	339..361	CDD:290200	11/21 (52%)
		C2H2 Zn finger	352..372	CDD:275368	7/19 (37%)
		zf-H2C2_2	364..389	CDD:290200	11/24 (46%)
		C2H2 Zn finger	380..396	CDD:275368	6/15 (40%)
Bcl6b	NP_001101749.1	BTB	28..132	CDD:279045
		BTB	39..131	CDD:197585
		C2H2 Zn finger	323..343	CDD:275368	6/19 (32%)
		zf-H2C2_2	335..360	CDD:290200	11/24 (46%)
		C2H2 Zn finger	351..371	CDD:275368	4/19 (21%)
		zf-H2C2_2	363..388	CDD:290200	9/24 (38%)
		C2H2 Zn finger	379..399	CDD:275368	6/19 (32%)
		zf-H2C2_2	391..416	CDD:290200	12/24 (50%)
		C2H2 Zn finger	407..427	CDD:275368	7/19 (37%)
		zf-H2C2_2	420..444	CDD:290200	11/23 (48%)
		C2H2 Zn finger	435..453	CDD:275368	7/17 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	156	1.000	Inparanoid score	I4200
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050