DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14655 and sna

DIOPT Version :9

Sequence 1:	NP_649494.1	Gene:	CG14655 / 40594	FlyBaseID:	FBgn0037275	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster

Alignment Length:	348	Identity:	81/348 - (23%)
Similarity:	140/348 - (40%)	Gaps:	41/348 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 SLMAQEGNESPANGQPASSRGFL--AAAPPKRRAKRTRSKPVVPTPPPVRTTPPAHCDICEFSFR 122
            ||......|:....||...|.::  .:..|:|.:..:.:..::  .|||...          .:.
  Fly    45 SLKRGRDEETQDYQQPEPKRDYVLNLSKTPERNSSSSSNSCLL--SPPVEAQ----------DYL 97

  Fly   123 NTELRDMHVRLVHENAEGEPKQKEPQQKEPDQEPYKCHL-CSKTFRMKGSLRIHLKVVHMMGVPC 186
            .||:   |:|.:.....|. ....|....|.|..:.... |:....:..|.:.||..........
  Fly    98 PTEI---HMRGLTAGTTGY-TTATPTTINPFQSAFVMAAGCNPISALWSSYQPHLAAFPSPASSM 158

  Fly   187 SNPN-----PNPNPSPTPASTTSAVTATPKLSICDRIR-----HTEPGALGNGNNSTCTASQPYA 241
            ::|.     ....|..:|.|.....:....||:.:.|.     |....|..:.:.::.::|..|:
  Fly   159 ASPQSVYSYQQMTPPSSPGSDLETGSEPEDLSVRNDIPLPALFHLFDEAKSSSSGASVSSSSGYS 223

  Fly   242 LSGALSMLQQSPSSPESGTATPKLWECDVCSKSFTTKYFLKKHKRLH-------TGEMPYTCEIC 299
            .:.|:|   .|.:|..:..|....::||.|.|.::|...|.||::.|       ..:..::||.|
  Fly   224 YTPAMS---ASSASVAANHAKNYRFKCDECQKMYSTSMGLSKHRQFHCPAAECNQEKKTHSCEEC 285

  Fly   300 ARTFTFQQSYHKHLLYHSEVKPHVCGVCGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVS 364
            .:.:|...:...|:..|:  .|..|.:||:||.....|..|.|.|:|||||:|..|.:.|..|.:
  Fly   286 GKLYTTIGALKMHIRTHT--LPCKCPICGKAFSRPWLLQGHIRTHTGEKPFQCPDCPRSFADRSN 348

  Fly   365 FLVHTRIHTGVMPYKCELCQKTF 387
            ...|.:.|..|..|.|::|.|:|
  Fly   349 LRAHQQTHVDVKKYACQVCHKSF 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14655	NP_649494.1	C2H2 Zn finger	268..288	CDD:275368	8/19 (42%)
		zf-H2C2_2	281..304	CDD:290200	7/29 (24%)
		C2H2 Zn finger	324..344	CDD:275368	8/19 (42%)
		zf-H2C2_2	339..361	CDD:290200	11/21 (52%)
		C2H2 Zn finger	352..372	CDD:275368	5/19 (26%)
		zf-H2C2_2	364..389	CDD:290200	8/24 (33%)
		C2H2 Zn finger	380..396	CDD:275368	4/8 (50%)
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	8/19 (42%)
		zf-H2C2_2	321..344	CDD:290200	11/22 (50%)
		zf-C2H2	334..356	CDD:278523	6/21 (29%)
		C2H2 Zn finger	336..356	CDD:275368	5/19 (26%)
		zf-H2C2_2	348..373	CDD:290200	8/24 (33%)
		C2H2 Zn finger	364..380	CDD:275368	4/8 (50%)
		C2H2 Zn finger	247..267	CDD:275368	8/19 (42%)
		C2H2 Zn finger	282..302	CDD:275368	5/19 (26%)
		zf-C2H2	306..328	CDD:278523	8/21 (38%)
		COG5048	307..>356	CDD:227381	19/48 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050