DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14655 and CG17612

DIOPT Version :9

Sequence 1:	NP_649494.1	Gene:	CG14655 / 40594	FlyBaseID:	FBgn0037275	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_608824.1	Gene:	CG17612 / 33639	FlyBaseID:	FBgn0031597	Length:	618	Species:	Drosophila melanogaster

Alignment Length:	330	Identity:	63/330 - (19%)
Similarity:	112/330 - (33%)	Gaps:	124/330 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 DICEFSFRNTELRDMHVRLVHE------NAEGEPKQKEPQQKE-PDQEPYKCHLCSKTFRMKGSL 172
            |:.:.:|.:.|.::..:::..:      :.:..|.:.:|...| ..:.|::|..|.|.|.:...|
  Fly   239 DVVKNAFDDLESKENTIQMYRQPKEEIIDIDSIPVKNKPVDYEVTGKPPHRCPQCPKIFLLAAKL 303

  Fly   173 RIHLKVVHMMGVPCSNPNPNPNPSPTPASTTSAVTATPKLSICDRIRHTEPGALGNGNNSTCTAS 237
            :.|:: .|                                   :..|.|||
  Fly   304 QAHIR-TH-----------------------------------NETRTTEP-------------- 318

  Fly   238 QPYALSGALSMLQQSPSSPESGTATPKLWECDVCSKSFTTKYFLKKHKRLHTG--------EMPY 294
                                     |:| :|.:|...:..:..|:.|..:|..        |.||
  Fly   319 -------------------------PRL-KCPMCPSIYMKRGCLEAHMWIHRASDERESELEPPY 357

  Fly   295 TCEICARTFTFQQSYHKHLLYHSEV-------KPHVCGVCGRAFKELSTLHNHQRIHSGEKPFKC 352
            .|..|.:.|.:......|:..|.:|       ..|.|..|...|.::|:|.:|.:||:||:.|||
  Fly   358 RCPHCPKLFLYSSFLEIHIQTHEDVSQRLSRKSSHKCAQCADVFSDVSSLKDHVKIHAGERTFKC 422

  Fly   353 EVCGKCFRQRVSF----LVHTRI----------------------HTGVMPYKCELCQKTFRYKV 391
            .:|...|::..:.    ..|||.                      ||...|:||..||:||:.:.
  Fly   423 PLCLMSFQEESNLKSHDCAHTRFKCHKCSKFFESQNYLDFHFKKSHTTKGPFKCIKCQQTFQKRN 487

  Fly   392 SQRTH 396
            ..:.|
  Fly   488 GLKEH 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14655	NP_649494.1	C2H2 Zn finger	268..288	CDD:275368	4/19 (21%)
		zf-H2C2_2	281..304	CDD:290200	8/30 (27%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		zf-H2C2_2	339..361	CDD:290200	10/21 (48%)
		C2H2 Zn finger	352..372	CDD:275368	6/45 (13%)
		zf-H2C2_2	364..389	CDD:290200	12/50 (24%)
		C2H2 Zn finger	380..396	CDD:275368	5/15 (33%)
CG17612	NP_608824.1	zf-AD	187..>246	CDD:285071	1/6 (17%)
		C2H2 Zn finger	290..310	CDD:275368	6/20 (30%)
		C2H2 Zn finger	323..343	CDD:275370	4/19 (21%)
		zf-C2H2_8	356..438	CDD:292531	24/81 (30%)
		C2H2 Zn finger	359..379	CDD:275368	4/19 (21%)
		C2H2 Zn finger	394..414	CDD:275368	6/19 (32%)
		C2H2 Zn finger	422..438	CDD:275368	3/15 (20%)
		C2H2 Zn finger	447..463	CDD:275368	0/15 (0%)
		C2H2 Zn finger	476..505	CDD:275368	6/17 (35%)
		C2H2 Zn finger	513..533	CDD:275368
		C2H2 Zn finger	545..565	CDD:275368
		C2H2 Zn finger	568..584	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100