DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14655 and CG3032

DIOPT Version :9

Sequence 1:	NP_649494.1	Gene:	CG14655 / 40594	FlyBaseID:	FBgn0037275	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001284974.1	Gene:	CG3032 / 31648	FlyBaseID:	FBgn0029928	Length:	431	Species:	Drosophila melanogaster

Alignment Length:	330	Identity:	90/330 - (27%)
Similarity:	132/330 - (40%)	Gaps:	55/330 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 KPVVPTPPPVRTTPPA------------------HCDICEFSFRNTELRDMHVRLVHENAEGEPK 143
            :|..|.|.|.....||                  .|.:|..||.:......|:|.|||.:
  Fly   123 EPPEPAPDPDPIDEPAIKSDKSPRKSFRGSRNTLKCSVCRRSFAHQITLAAHIRKVHEGS----- 182

  Fly   144 QKEPQQKEPDQEPYKCHLCSKTFRMKGSLRIHLKVVHMMGVPCSNPNPNPNPSPTPASTTSAVTA 208
                      :.|::|..|.|.:...|.|..|::.||   .|....:|...|......|:.....
  Fly   183 ----------KRPFQCDQCEKAYSFMGGLYTHIREVH---APKERRHPCDQPGCERIYTSRIAMQ 234

  Fly   209 TPKLSICDRIRHT--EPGALGNGNNSTCTASQPYALSGALSMLQQSPSSPE----SGTATPKLWE 267
            ..|     |::|:  :..||.......|.||...:.:....:..:.|:..|    .|.|..:.:
  Fly   235 KHK-----RLKHSPRDRDALKKFICEQCGASFNQSANLKYHLKTKHPTEDEVAAREGGAGERHF- 293

  Fly   268 CDVCSKSFTTKYFLKKHK-RLH--TGEMPYTCEICARTFTFQQSYHKHLLYHSEVK-PHVCGVCG 328
            ||:|.|.|.::|.||.|. :.|  ..|:|:.|::|.|....:....:|:|.||..| |  |..||
  Fly   294 CDICQKEFHSRYTLKYHTLQQHEVQEELPHECQVCGRRMAKKFMLLQHMLMHSNDKLP--CEHCG 356

  Fly   329 RAFKELSTLHNHQR-IHSGEKPFKCEVCGKCFRQRVSFLVHTRIHTGVMPYKCELCQKTFRYKVS 392
            |.|.....|..|.| :|...|||.|..|.:.|..|.:...|..||||..||.|:.|.:.||.:..
  Fly   357 RRFARRFELEAHVRAVHLKLKPFPCHHCPESFASRKTLRHHEYIHTGEKPYICDTCGQAFRQQTC 421

  Fly   393 QRTHR 397
            .:.||
  Fly   422 LKNHR 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14655	NP_649494.1	C2H2 Zn finger	268..288	CDD:275368	9/20 (45%)
		zf-H2C2_2	281..304	CDD:290200	9/25 (36%)
		C2H2 Zn finger	324..344	CDD:275368	8/20 (40%)
		zf-H2C2_2	339..361	CDD:290200	9/22 (41%)
		C2H2 Zn finger	352..372	CDD:275368	5/19 (26%)
		zf-H2C2_2	364..389	CDD:290200	10/24 (42%)
		C2H2 Zn finger	380..396	CDD:275368	4/15 (27%)
CG3032	NP_001284974.1	zf-AD	13..95	CDD:285071
		C2H2 Zn finger	158..179	CDD:275368	6/20 (30%)
		C2H2 Zn finger	188..209	CDD:275368	6/20 (30%)
		C2H2 Zn finger	218..239	CDD:275368	3/25 (12%)
		C2H2 Zn finger	254..275	CDD:275368	3/20 (15%)
		C2H2 Zn finger	294..315	CDD:275368	9/20 (45%)
		C2H2 Zn finger	325..345	CDD:275368	5/19 (26%)
		C2H2 Zn finger	352..373	CDD:275368	8/20 (40%)
		C2H2 Zn finger	381..401	CDD:275368	5/19 (26%)
		C2H2 Zn finger	409..429	CDD:275368	6/18 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	42	1.000	Inparanoid score	I2696
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050