DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14655 and Bcl6

DIOPT Version :9

Sequence 1:NP_649494.1 Gene:CG14655 / 40594 FlyBaseID:FBgn0037275 Length:525 Species:Drosophila melanogaster
Sequence 2:NP_001100554.1 Gene:Bcl6 / 303836 RGDID:1309345 Length:707 Species:Rattus norvegicus


Alignment Length:491 Identity:123/491 - (25%)
Similarity:185/491 - (37%) Gaps:117/491 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MCSTSVLCPLCAVPSFGSIDALQQRLIKAANGPL-ACPFANCKELF------------LGLDKLT 52
            :|.:::..|..|||.    :|..........||. |.|.|.....|            ...|::.
  Rat   254 LCHSNIYSPKEAVPE----EARSDIHYSVTEGPKPAAPSARHASYFPCDKASKEEERPSSEDEIA 314

  Fly    53 IHLFSHTSLMAQEGNESPANGQPASSRGFLAAAPPKRRAKRTRSK-----PVVPTPPPVRTTPPA 112
            :|.....:.:.::|..||.:.|.:..:       |....:.:.||     ....:||....|.|.
  Rat   315 LHFEPPNAPLNRKGLVSPQSPQKSDCQ-------PNSPTESSSSKNACILQASGSPPAKSPTDPK 372

  Fly   113 HCDICEFSFRNTELRDMHVRLVHENAEGEPKQK------------EPQQKEPDQEPYKCHLCSKT 165
            .|:..::.|       :.:..:::||:.|..::            .|...:|..||....|.|.|
  Rat   373 ACNWKKYKF-------IVLNSLNQNAKPEGSEQAELGRLSPRAYPAPPACQPPMEPANLDLQSPT 430

  Fly   166 FRMKGS---------LRIHLKVVH--MMGVPCSNPNPNPNPSPTPASTTSAVTATPKLSICDRIR 219
             ::..|         .|:: .:|:  :.|.|.|:...:......|...||..:.:|        :
  Rat   431 -KLSASGEDSTIPQASRLN-NIVNRSLAGSPRSSSESHSPLYMHPPKCTSCGSQSP--------Q 485

  Fly   220 HTEPGALGNGNNSTC--TASQPYALSGALSMLQQSPSSPESG----------------------- 259
            |||          .|  ||...:......:..:.|.||.|:|                       
  Rat   486 HTE----------MCLHTAGPTFPEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHTLQ 540

  Fly   260 TATPKLWECDVCSKSFTTKYFLKKHKRLHTGEMPYTCEICARTFTFQQSYHKHLLYHSEVKPHVC 324
            |.:.|.::||.|..||..|..|..||.:||||.||.|.||...|....:...|...||..||:.|
  Rat   541 THSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKC 605

  Fly   325 GVCGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSFLVHTRIHTGVMPYKCELCQKTFRY 389
            ..||..|.:::.|..|..||:||||:.||:||..||...:...|.|||||..||.||.|...||:
  Rat   606 ETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRH 670

  Fly   390 KVSQRTH-------------RCPTEEAQTPEQLIKA 412
            |...|.|             :.....|..|.:|.||
  Rat   671 KSQLRLHLRQKHGAITNTKVQYRVSAADLPPELPKA 706

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14655NP_649494.1 C2H2 Zn finger 268..288 CDD:275368 9/19 (47%)
zf-H2C2_2 281..304 CDD:290200 12/22 (55%)
C2H2 Zn finger 324..344 CDD:275368 6/19 (32%)
zf-H2C2_2 339..361 CDD:290200 12/21 (57%)
C2H2 Zn finger 352..372 CDD:275368 8/19 (42%)
zf-H2C2_2 364..389 CDD:290200 12/24 (50%)
C2H2 Zn finger 380..396 CDD:275368 7/15 (47%)
Bcl6NP_001100554.1 BTB_POZ_ZBTB27_BCL6 8..125 CDD:349640
PHA03247 <173..427 CDD:223021 34/190 (18%)
C2H2 Zn finger 521..542 CDD:275368 0/20 (0%)
C2H2 Zn finger 549..569 CDD:275368 9/19 (47%)
zf-H2C2_2 561..586 CDD:404364 13/24 (54%)
C2H2 Zn finger 577..597 CDD:275368 5/19 (26%)
zf-H2C2_2 589..614 CDD:404364 9/24 (38%)
C2H2 Zn finger 605..625 CDD:275368 6/19 (32%)
zf-H2C2_2 617..642 CDD:404364 13/24 (54%)
C2H2 Zn finger 633..653 CDD:275368 8/19 (42%)
zf-H2C2_2 646..670 CDD:404364 12/23 (52%)
C2H2 Zn finger 661..679 CDD:275368 8/17 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 156 1.000 Inparanoid score I4200
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.050

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