Protein Alignment CG14655 and ZNF358

DIOPT Version :10

• Sequence 1: NP_649494.1
• Gene: CG14655 / 40594
• FlyBaseID: FBgn0037275
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_047294137.1
• Gene: ZNF358 / 140467
• HGNCID: 16838
• Length: 587
• Species: Homo sapiens
• Alignment Length: 382
• Identity: 103/382 - (26%)
• Similarity: 148/382 - (38%)
• Gaps: 99/382 - (25%)

  Fly    94 TRSKPVVPTPPPVRTTP-----PAHCDICEFSFRNTELRDMHVRLVHENAEGEPKQKEP------ 147
            |.:..|:.|.|.|...|     |..|..|..:||.:.....| |..|   .||...:.|
Human   147 TATPQVLATSPAVLPAPASPPRPFSCPDCGRAFRRSSGLSQH-RRTH---SGEKPYRCPDCGKSF 207

  Fly   148 -------QQK--EPDQEPYKCHLCSKTFRMKGSLRIHLKVVHMMGVPCSNPNPNPNPSPTPASTT 203
                   |.:  .....||:|..|.|.|..:.:|..|..         |:....|:..|
Human   208 SHGATLAQHRGIHTGARPYQCAACGKAFGWRSTLLKHRS---------SHSGEKPHHCP------ 257

  Fly   204 SAVTATPKLSICDRIRHTEPGALGNGNNSTCTASQPYALSGALSMLQQSPSSPESGTATPKLWEC 268
                      :|.:       |.|:|                 |:|.|...: ..|   |:..:|
Human   258 ----------VCGK-------AFGHG-----------------SLLAQHLRT-HGG---PRPHKC 284

  Fly   269 DVCSKSFTTKYFLKKHKRLHTGEMPYTCEICARTFTFQQSYHKHLLYHSEVKPHVCGVCGRAFKE 333
            .||:|.|.....|.||.|.||||.||.|..|.:.|....:..:|...|:..:|:.|..||:||.:
Human   285 PVCAKGFGQGSALLKHLRTHTGERPYPCPQCGKAFGQSSALLQHQRTHTAERPYRCPHCGKAFGQ 349

  Fly   334 LSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSFLVHTRIHTGVMPYKCELCQKTFRYKVSQRTHRC 398
            .|.|.:|.|||:||:|:.|..|.|.|.|..:.|.|..:|:|..||:|:||.|.|....|...|
Human   350 SSNLQHHLRIHTGERPYACPHCSKAFGQSSALLQHLHVHSGERPYRCQLCGKAFGQASSLTKH-- 412

  Fly   399 PTEEAQTPEQLIKAFLEGNDSHTQPSPASAEIAA--------INSSSIVDPEQEALL 447
                        |...||..:....:.|:|..||        ::.:|::.|.|.:||
Human   413 ------------KRVHEGAAAAAAAAAAAAAAAAAGLGLGPGLSPASMMRPGQVSLL 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14655	NP_649494.1	SUF4-like	<157..>180	CDD:411020	7/22 (32%)
		C2H2 Zn finger	159..180	CDD:411020	6/20 (30%)
		SFP1	<264..345	CDD:227516	31/80 (39%)
		C2H2 Zn finger	268..288	CDD:275368	9/19 (47%)
		C2H2 Zn finger	324..344	CDD:275368	9/19 (47%)
		zf-H2C2_2	340..361	CDD:463886	11/20 (55%)
		C2H2 Zn finger	352..372	CDD:275368	7/19 (37%)
		zf-H2C2_2	368..389	CDD:463886	10/20 (50%)
		C2H2 Zn finger	380..396	CDD:275368	6/15 (40%)
ZNF358	XP_047294137.1	COG5048	<54..358	CDD:227381	67/267 (25%)
		C2H2 Zn finger	172..192	CDD:275368	6/20 (30%)
		zf-H2C2_2	185..209	CDD:463886	6/27 (22%)
		C2H2 Zn finger	200..220	CDD:275368	2/19 (11%)
		C2H2 Zn finger	228..248	CDD:275368	6/28 (21%)
		C2H2 Zn finger	256..276	CDD:275368	8/60 (13%)
		C2H2 Zn finger	284..304	CDD:275368	9/19 (47%)
		C2H2 Zn finger	312..332	CDD:275368	4/19 (21%)
		C2H2 Zn finger	340..360	CDD:275368	9/19 (47%)
		zf-H2C2_2	352..375	CDD:463886	11/22 (50%)
		C2H2 Zn finger	368..388	CDD:275368	7/19 (37%)
		zf-H2C2_2	380..403	CDD:463886	10/22 (45%)
		zf-C2H2	394..416	CDD:395048	9/35 (26%)
		C2H2 Zn finger	396..416	CDD:275368	8/33 (24%)