DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment atms and SPAC664.03

DIOPT Version :9

Sequence 1:	NP_001262263.1	Gene:	atms / 40593	FlyBaseID:	FBgn0010750	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_593451.2	Gene:	SPAC664.03 / 2543560	PomBaseID:	SPAC664.03	Length:	456	Species:	Schizosaccharomyces pombe

Alignment Length:	491	Identity:	115/491 - (23%)
Similarity:	204/491 - (41%)	Gaps:	84/491 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 RKSEIICRVKYGNNLPDIPFDLKFLQYPFDSHRFVQYN-PTSLERNFKYDVLTEHDLGVTVDLIN 87
            |:.:.|.||:|.|.||..||..|.:..|....::...| .::|.:..|..:..:.:||:.:||..
pombe     4 RRQDYILRVRYHNPLPPPPFPPKLINIPNPVKQYALPNFVSTLVQEKKIPIENDIELGMPLDLAG 68

  Fly    88 -RELYQAD--------SMTLLDPADEKLLEEETLTPTDSVRSRQHSRTVSWLRKSEYISTEQTRF 143
             ...::.|        |...|||.|..||:.       :..|......|.:||::||||:|..|
pombe    69 ITGFFEGDTSWMHSDLSSVNLDPIDRSLLKV-------AGGSGSTHLEVPFLRRTEYISSEVAR- 125

  Fly   144 QPQNLENIEAKVGYNVKKSLREETLYLDREA--QIKAIEKTFSDTKS--EITKHYSKPNVVPVEV 204
            ...|..|:  ::..:..|:|.|:.....||.  |::||.::|...:.  |..||.:||::.||..
pombe   126 AASNRGNL--RLTASTSKALAEQRGRSLREVPKQLEAINESFDVVQQPLEQLKHPTKPDLKPVSA 188

  Fly   205 LPIFPD--FTNWKFPCAQVIFDSDPAPAGKNVPAQLEEMSQAMIRGVM------DESGEQFVAYF 261
            ..:.|:  ....:....:|..|........:....|:|......|..:      ...||:|::|:
pombe   189 WNLLPNTSMAGIQHLMLRVADDLSERSHSYSSLVNLQEGHNLTKRHEVALFMPSSAEGEEFLSYY 253

  Fly   262 LPTEQTLEKRRTDFINGELYKEEEEYEYKIAREYNWNVKTKASKGYEENYF-FVMRQD-----GI 320
            ||:|:|.|:.:.. :|.......|.:.|...|.::.::... |.|.|:... |...:|     .:
pombe   254 LPSEETAEEIQAK-VNDASADVHEPFVYNHFRNFDASMHVN-STGLEDLCLTFHTDKDHPEANQV 316

  Fly   321 YYNELETRVRLNKRRVKVGQQPNNTKLV----VKHRPL---DSMEHRMQRYRERQLEVPGEEEEI 378
            .|..:..|..|.:|.|:.   |.:...|    :..|.|   :|::.:..||....|   |..:::
pombe   317 LYTPIYARSTLKRRHVRA---PVSLDAVDGIELSLRDLNDEESLQLKRARYDTFGL---GNIKDL 375

  Fly   379 VEEVREEEQMQIIGE-TEKTSEDAAVGAQAASGADSPAQVARDRQSRSRSRTRSGSSSGSGSGSG 442
            .||  ||:...:.|. .|:.||:           :.||:        ||.:..|...:.
pombe   376 EEE--EEKLRSVEGSLNEELSEE-----------EKPAE--------SREQLESAEQTN------ 413

  Fly   443 SRASSRSKSGSRSGSGSRSRTNSPAGSQKSGSRSRS 478
               ..:.::.:::.|.|.|:.||||...:.|:...|
pombe   414 ---GVKPETQAQNMSASESQANSPAPPVEEGNTQPS 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
atms	NP_001262263.1	Paf1	27..414	CDD:281915	100/422 (24%)
SPAC664.03	NP_593451.2	Paf1	7..430	CDD:281915	107/470 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	59	1.000	Domainoid score	I3069
eggNOG	1	0.900	-	-		E1_KOG2478
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	65	1.000	Inparanoid score	I1969
OMA	1	1.010	-	-		QHG55946
OrthoFinder	1	1.000	-	-		FOG0004172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104057
Panther	1	1.100	-	-	LDO	PTHR23188
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R886
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.900