Protein Alignment CG44098 and Slc22a7

DIOPT Version :10

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_445989.2
• Gene: Slc22a7 / 89776
• RGDID: 621699
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 578
• Identity: 131/578 - (22%)
• Similarity: 225/578 - (38%)
• Gaps: 112/578 - (19%)

  Fly   214 GPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPPHTIGA----QNQTQWIKVSH 274
            |.:|.:|||.::|:.|.::.........:|.|..|.|   .|..|   ||    .:|..|::...
  Rat    11 GGFGPFQLRNLVLMALPRMLLPMHFLLPVFMAAVPAH---HCALP---GAPANLSHQDLWLEAHL 69

  Fly   275 PQKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENSDQEPRVWEKPLHRNSNVIPCT---EFQHES 336
            |::   .|..||......|.....:........||. ||.  .:||     .:||:   |:....
  Rat    70 PRE---TDGSFSSCLRFAYPQTVPNVTLGTEVSNSG-EPE--GEPL-----TVPCSQGWEYDRSE 123

  Fly   337 DYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFGMITQIFCGNLTG 401
            ...::.|::||||.:..|..:|......|||.|.::...|...|..|.::|...::.:..|.::.
  Rat   124 FSSTIATEWDLVCQQRGLNKITSTCFFIGVLVGAVVYGYLSDRFGRRRLLLVAYVSSLVLGLMSA 188

  Fly   402 HVASYELHVFFRCLSAVCCAQMYTAGGQIMADIT-----------GGKYRTCVSTLFEQFWSIGV 455
            ...:|.:.|..|.|:           |..:|..|           ..::||....:...|||.||
  Rat   189 ASINYIMFVVTRTLT-----------GSALAGFTIIVLPLELEWLDVEHRTVAGVISTVFWSGGV 242

  Fly   456 MMLPGVASFWSSWSHLYMAISWPTVI-LIYLWQWIPDSPRWLIARGRTQDAKKILLECVEVNGTG 519
            ::|..|.....||..|.:|.:.|.|. :|.:| |:|:|.|||:.:||.::|||.||.|.::||..
  Rat   243 LLLALVGYLIRSWRWLLLAATLPCVPGIISIW-WVPESARWLLTQGRVEEAKKYLLSCAKLNGRP 306

  Fly   520 YN--------LPHDIDQQLELQAQTAMDAPPPSGWWSMWKGERAVRHI-VCVHLAWSLYIVVYYG 575
            ..        |.:.:..:..||..:.:|....|          .:||| :|..:.|......|||
  Rat   307 VGEGSLSQEALNNVVTMERALQRPSYLDLFRTS----------QLRHISLCCMMVWFGVNFSYYG 361

  Fly   576 MLLNIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIAYCGWLVPKP 640
            :.|::..... ::|......|..|:.......||:.:..|:             :...|.|:...
  Rat   362 LTLDVSGLGL-NVYQTQLLFGAVELPSKIMVYFLVRRLGRR-------------LTEAGMLLGAA 412

  Fly   641 SVIGLDPNVALLMCSAMVSKMAISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLLGAPFIG 705
            ...|....|:|...|.:.:.:.:....|.....|..|.:.:     .:.|:       |....:|
  Rat   413 LTFGTSLLVSLETKSWITALVVVGKAFSEAAFTTAYLFTSE-----LYPTV-------LRQTGLG 465

  Fly   706 STVVFGQ-----------------LIPQTAFASLAILGGLCTSLISSPRTHPISRPSS 746
            .|.:.|:                 |:|:.|:..:|::.. ||:|: .|.|.....|.:
  Rat   466 LTALMGRLGASLAPLAALLDGVWLLLPKVAYGGIALVAA-CTALL-LPETKKAQLPET 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	MFS_SLC22	329..732	CDD:340875	98/443 (22%)
Slc22a7	NP_445989.2	2A0119	11..521	CDD:273328	131/576 (23%)