Protein Alignment CG44098 and GIT1

DIOPT Version :10

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_010022.1
• Gene: GIT1 / 850462
• SGDID: S000000695
• Length: 518
• Species: Saccharomyces cerevisiae
• Alignment Length: 548
• Identity: 93/548 - (16%)
• Similarity: 159/548 - (29%)
• Gaps: 221/548 - (40%)

  Fly   308 NSDQEPRVWEKPLHRNSNVIPCTEFQHESDYHSVVTQYDLVCSRDILVS----------VTQFF- 361
            |.:..||:.:....|.:.   .||...:..:.::||   ::.|...|:|          :.:.|
Yeast    15 NENTNPRIIKYDAERRAT---RTETSKKDKWKNIVT---IIASGFALISDGYVNGSMSMLNKVFV 73

  Fly   362 -------------------HLFGVLTGGILANQLLKYFSPRNVML-------------------- 387
                               .|.|::.|.........|:|.::.:|
Yeast    74 MEYGKKNYSSKVSTRVSNAALVGIIFGQFFMGIAADYYSRKSCILVATAILVIGSALCAASHGTT 138

  Fly   388 ----FGMITQIFCGNL-TGHVASYELHVFFRCLSAVCCAQMYTA--GGQIMADIT------GGKY 439
                |.|:| :..|.: .|..|.|....    |||...|..||.  .|.|:..:|      ||.:
Yeast   139 VPGMFWMLT-VMRGLVGIGVGAEYPTST----LSANESANEYTTTKRGGILVMVTNLPLAFGGPF 198

  Fly   440 RTCVSTLFEQFWSIGVMMLPGVASFWSSWSHLY-MAISWPTVILIYLWQWIPDSPRWLIARGRTQ 503
            .|.:..:..:..|       |.....:.|..:: :...||..:..:.|
Yeast   199 ATIIFLIVYKICS-------GTKHLEAIWRTVFAIGCFWPLSVFYFRW----------------- 239

  Fly   504 DAKKILLECVEVNGTGYNLPHDIDQQLELQAQTAMDAPPPSGWWSMWKGERAVRHIVCVHLAWSL 568
              |....|..|......|:|:.:..:.               :|....|       .|.  .|.:
Yeast   240 --KTATTEVYEKGRIKRNIPYFLALKF---------------YWKRLLG-------TCG--TWFM 278

  Fly   569 YIVVYY--GMLLN--IRSFSRDHLYIN--------TFFAGFSEMMGTFFGLFLILKTTRKWL--- 618
            |..|.:  |:..:  |.|..:|.   |        ....|...::|...|.:|..:..||:.
Yeast   279 YDFVTFPNGIFSSTIISSVIKDQ---NDLVKVAEWNLLLGVLAVLGVPIGAYLSDRIGRKYTLMF 340

  Fly   619 -WTG--LFNIVAGCIAYCGWLVPKPSVIGLDPNVALLMCSAMVSKMAISTTLSILTTCTVELVSD 680
             ::|  :|.::.|| ||                                               |
Yeast   341 GFSGYIIFGLIIGC-AY-----------------------------------------------D 357

  Fly   681 DKKKITSFSTICWARFWLLG----APFIG-------STVVFGQLIPQTAFASLAILGGLCTSLIS 734
            ..||||....|.:|...:||    ...:|       :|.|.|      .|..|:.:.|...|::.
Yeast   358 QLKKITPLFIIFYAFMNMLGNAGPGDMLGVISSEASATAVRG------VFYGLSAVTGKIGSVVG 416

  Fly   735 SPRTHPISRPSSPAAQGTQNITSQFTII 762
            .....||          ..|:.:::|.|
Yeast   417 VECFQPI----------RDNLGARWTFI 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	MFS_SLC22	329..732	CDD:340875	83/495 (17%)
GIT1	NP_010022.1	MFS_PhT	48..454	CDD:340922	85/509 (17%)