Protein Alignment CG44098 and SLC22A23

DIOPT Version :10

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: XP_054212174.1
• Gene: SLC22A23 / 63027
• HGNCID: 21106
• Length: 718
• Species: Homo sapiens
• Alignment Length: 498
• Identity: 98/498 - (19%)
• Similarity: 184/498 - (36%)
• Gaps: 117/498 - (23%)

  Fly   345 YDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFGMITQIFCG---NLTGHVASY 406
            :||||.....|.:.:|..|.|::.|.::...:..:...|.|:||.:|..:..|   .|:.:|..:
Human   243 WDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMF 307

  Fly   407 ELHVFFR--CLSAVCCA------QMYTAGGQIMADITGGKYRTCVSTLFEQFWSI-GVMMLPGVA 462
            ....||.  ||:.:...      ::...|.:.|.            |:...|.:: |..::||:|
Human   308 STLRFFEGFCLAGIILTLYALRIELCPPGKRFMI------------TMVASFVAMAGQFLMPGLA 360

  Fly   463 SFWSSWSHLYMAISWPTVILIYLWQWIPDSPRWLIARGRTQDAKKILLECVEVNGTGYNLPHDID 527
            :....|..|...|..|.::::..|...|:|.|||:|..:.:.||:::|...:.|  ..|...||.
Human   361 ALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKN--RMNPEGDIK 423

  Fly   528 QQL-ELQAQTAMDAPPPS-------GWWSMWKGERAVRHIVCVHLAWSLYIVVYYGMLLNIRSFS 584
            ..: ||:.:  :...|..       |..::||.    ..::||:      .:..||:   ...|:
Human   424 GVIPELEKE--LSRRPKKVCIVKVVGTRNLWKN----IVVLCVN------SLTGYGI---HHCFA 473

  Fly   585 RDHL-------YINTFFAGFSE-------------MMGTFFG------LFLILKTTRKWLWTGLF 623
            |..:       .:..|:|.:..             ::..|.|      ||:||......|..||.
Human   474 RSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLL 538

  Fly   624 NIVAGCIAYCGWLVPKPSVIGLDPNV----------ALLMCSAMVSKMAI----STTLSILTTCT 674
            |::.....:....:.....:|:..:|          ..:..|..|..:::    ..|.:::....
Human   539 NLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGG 603

  Fly   675 VELVSDDKKKITSFSTICWARFWLLGAPFIGSTVVFGQLIPQTAFASLAILGGLCTSLISSPR-- 737
            :.||            :..|.|.:|.||.|......|..:....||...::..:|..|:...|
Human   604 LGLV------------LASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQ 656

  Fly   738 ---------THPISRPSSPAAQGTQNITSQFTIIDGMDNKGYS 771
                     .|...:|..|..:|.|.:     ::...:.|.||
Human   657 NLPENISNGEHYTRQPLLPHKKGEQPL-----LLTNAELKDYS 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	MFS_SLC22	329..732	CDD:340875	88/446 (20%)
SLC22A23	XP_054212174.1	MFS_SLC22A23	192..637	CDD:341002	85/434 (20%)