DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG44098 and slc22a13b

DIOPT Version :9

Sequence 1:	NP_001262264.1	Gene:	CG44098 / 40590	FlyBaseID:	FBgn0264907	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	XP_017209322.1	Gene:	slc22a13b / 556601	ZFINID:	ZDB-GENE-061013-532	Length:	549	Species:	Danio rerio

Alignment Length:	553	Identity:	128/553 - (23%)
Similarity:	236/553 - (42%)	Gaps:	91/553 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 GPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQTQWIKVSHPQKE 278
            |.:|.:|.|.::.:.|..|.:::.|...:|||.:..|   :|          .:.||....|...
Zfish    12 GEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISFPH---YC----------NSSWILRQAPNLT 63

  Fly   279 ESD--------DQEFSIDFCNVY----QDAQEHAHHYYNYENSDQEPRVWEKPLHRNSNVIPCTE 331
            |..        |.:...:.|.::    .|.::..|:..|...|..:..|::.|
Zfish    64 EEKQLNLTVPLDSKGQYESCKMFTPVEMDIEDIEHYGINTTTSCIDGWVYKAP------------ 116

  Fly   332 FQHESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFGMITQIFC 396
                .|..:::|::||||...:....:|..::.|:|.|.:|...:...:..|...|..:..|...
Zfish   117 ----KDSSTLITEFDLVCENKVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQFLS 177

  Fly   397 GNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQIM----------ADITGGKYRTCVSTLFEQFW 451
            |  .|...|..::|:.        |..:..|..|.          .:..|...|...:.|...|:
Zfish   178 G--VGVAFSPNIYVYI--------ALRFVVGTTISGISINTFVLGTEWCGSAKRALFTILSHCFF 232

  Fly   452 SIGVMMLPGVASFWSSWSHLYMAISWPTVILIYLWQWI-PDSPRWLIARGRTQDAKKILLECVEV 515
            :||:|:|.|||....:|..|.:.:|.| |.|.:::.|| |:|.|||:.:|:...||:.:|:...:
Zfish   233 AIGLMLLSGVAYGIRNWRVLQLVLSAP-VGLFFIYYWILPESARWLLTQGKLDSAKREILKAARI 296

  Fly   516 NG--TGYNLPHDIDQQLELQAQTAMDAPPPSGWWSMWKGERAVRHIVCVHLAWSLYIVVYYGMLL 578
            ||  ...||...::.:...::.|.:|.     :...:..:||:  |:|  ..|.:..:||||:.|
Zfish   297 NGRKVSENLLDKMEAENTAKSSTMIDL-----FRVGYLRKRAL--IMC--YMWFVTSLVYYGVSL 352

  Fly   579 NIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAG--CIAYCGWLVPKPS 641
            |:.:|..| :|:.....|.:|.........||.:..|: :...:..::.|  |:..       |:
Zfish   353 NVGNFGLD-IYLTQLIFGMAEFPARLSCFPLIQRFGRR-ICQSVVLLLGGTACLII-------PA 408

  Fly   642 VIGLDPNVALLMCSAMVSKMAISTTLSILTTCTVELV-SDDKKKITSFSTICWARFWLLGAPFIG 705
            :....|.|..::  |::.|.:::.:.||:...|.||. :..::.....:::| ||...:.||.||
Zfish   409 IPAKYPIVVTVI--AVIGKFSLAASFSIVYVYTAELYPTVVRQNGVGLNSMC-ARVAGILAPLIG 470

  Fly   706 STVVFGQLIPQTAFASLAILGGLCTSLISSPRT 738
            ...|:...||...:.||..:||..|.|:  |.|
Zfish   471 LLDVYHHAIPMIIYGSLPFVGGALTFLL--PET 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	124/543 (23%)
CG44098	NP_001262264.1	MFS	353..733	CDD:119392	95/395 (24%)
slc22a13b	XP_017209322.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588671
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.850