Protein Alignment CG44098 and SLC22A17

DIOPT Version :9

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_065105.3
• Gene: SLC22A17 / 51310
• HGNCID: 23095
• Length: 649
• Species: Homo sapiens
• Alignment Length: 649
• Identity: 130/649 - (20%)
• Similarity: 203/649 - (31%)
• Gaps: 270/649 - (41%)

  Fly   205 KVDAVGQITGPWGKWQLRTVLLIFLCKIPSSWFMAC-----IIFTAPAPRHGEFFCKPPHTIGAQ 264
            :|.|:|      |..||:    :.||.:| ..|:|.     .|||...|.|..:...||:..|
Human    86 QVGALG------GGQQLQ----LGLCCLP-VLFVALGMASDPIFTLAPPLHCHYGAFPPNASG-- 137

  Fly   265 NQTQWIKVSHPQKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENSDQEPRVWEKPLHRN------ 323
                                                               ||:|.:.:
Human   138 ---------------------------------------------------WEQPPNASGVSVAS 151

  Fly   324 --------SNVIPCT----------EFQH---ESDYH-------SVVTQYDLVCSRDILVSVTQF 360
                    |.|...|          :|.|   :.||:       :.:.|:||||.....|.:.|.
Human   152 AALAASAASRVATSTDPSCSGFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQI 216

  Fly   361 FHLFGVLTGGILANQLLKYFSPRNVMLFGM-------ITQIFCGNLTGHVASYELHVFFRCLSAV 418
            ..:.|..:|.:........|..|.::|..:       :.....|:.||.:|       .|.|.
Human   217 LFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMA-------LRFLL-- 272

  Fly   419 CCAQMYTAGGQIMADITGGKY-----------RTCVSTLFEQFWSIGVMMLPGVASFWSSWSHLY 472
                     |.::|.:..|.|           |..|:...|.....|..:..|:|.....|..|.
Human   273 ---------GFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQ 328

  Fly   473 MAISWPTVI-LIYLWQWI-PDSPRWLIARGRTQDAKKILLECVEVNGTGYNLPHDIDQQLELQAQ 535
            ..|:.|.:: |.|.|..: .:|.||||.:.:.::|:.:|....|     .|.||  .|.|..:||
Human   329 RMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAE-----RNRPH--GQMLGEEAQ 386

  Fly   536 TAMD-----APPPSGWWSMWKGERAVRHIVCVHLAWSLYIVVYYGMLLNIRSFSRDHLYINTFFA 595
            .|:.     .|.|                     |.|.:   .:..|||.|     :::.|....
Human   387 EALQDLENTCPLP---------------------ATSSF---SFASLLNYR-----NIWKNLLIL 422

  Fly   596 GFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIAYCGWLVPKPSVIGLDPNVALLMCSAMVSK 660
            ||:                         |.:|..|.:|    .:|...|..|: ...:||.:.|.
Human   423 GFT-------------------------NFIAHAIRHC----YQPVGGGGSPS-DFYLCSLLASG 457

  Fly   661 MA---------------------ISTTLSILTTCTVELVSDDKKKITSFSTICWAR--------- 695
            .|                     :|.||:.:.:..:..:.|.:..|  |.|: ||:
Human   458 TAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDCEHPI--FPTV-WAQQGNPNRDLN 519

  Fly   696 ------FWLLG-----APFIGSTVVFGQLIPQTA-------FASLAILGGLCTSLISSP--RTH 739
                  |.:||     |..|.||::..::||.|.       ..:|..||||     |.|  |.|
Human   520 EAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGL-----SGPAQRLH 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	123/627 (20%)
		MFS	353..733	CDD:119392	92/452 (20%)
SLC22A17	NP_065105.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153298
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930