DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG44098 and CG6356

DIOPT Version :9

Sequence 1:	NP_001262264.1	Gene:	CG44098 / 40590	FlyBaseID:	FBgn0264907	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster

Alignment Length:	600	Identity:	132/600 - (22%)
Similarity:	212/600 - (35%)	Gaps:	124/600 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 QITGPWGK--WQLRTVLLIFLCKIP---SSWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQTQWI 270
            ::.|..|.  |     .:.|||..|   :.:.::........|  .:.:|..|..    ..|.|
  Fly    29 EVVGSGGAFVW-----AIFFLCVTPNILNGFHVSSYTLLGHLP--DDQWCGIPEL----QDTNW- 81

  Fly   271 KVSHPQKEESDDQEFSIDFCNVY--------QDAQEHAHHYYNYENSDQEP-----RVWEKPLHR 322
              :|.||.|...:......|.|:        :.:.|.|.:|..:......|     ||  |..|
  Fly    82 --THAQKREIVAKGLDSGGCTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRV--KGQH- 141

  Fly   323 NSNVIPCTEFQHESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTG----GILANQLLKYFSPR 383
                    ||.|...  :.|..:||.|.|.|..:..|.....|...|    ||||::..:..|..
  Fly   142 --------EFAHPET--TFVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFT 196

  Fly   384 NVMLFGMITQIFCGNLTGHVASYELHVFFR-CLSAVCCAQMYTAGGQIMADITGGKYRTCVSTLF 447
            ....|.::...||    .....|.|.:..| .|.|......|.|...|:.:|. .|:|:.:|..|
  Fly   197 LGAAFFIVGSFFC----TFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENIC-LKHRSWMSIAF 256

  Fly   448 EQFWSIGVMMLPGVASFWSSWSHLYMAISWPTVILIYLWQWIPDSPRWLIARGRTQDAKKILLEC 512
            ...:.:|:::|..|......|.||.:|::.|:::||.....:.:||||||...|.....|||..
  Fly   257 SASYPVGMIILAIVGYVIQPWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFR- 320

  Fly   513 VEVNGTGYNLPHDIDQQLELQAQTAMDAP-----------PPSGW--------------WSMWKG 552
                           |....|.|.|:.||           |..|:              ..::..
  Fly   321 ---------------QPSHYQIQPAVAAPSQVASDKKSLEPEEGFSFGQKLKNGPLKSIIELYAN 370

  Fly   553 ERAVRHIVCVHLAWSLYIVVYYGMLLNIRSFS-RDHLYINTFFAGFSEMMGTFFGLFLILKTTRK 616
            .:..|.|...:..:.:..:.||...||..:.| ..:|||  ...|..::......:.::..|.|:
  Fly   371 SKVRRMIFASYFMFCVTSLSYYVTALNAANLSVSRYLYI--IGTGLVDIPSYLVPVIMLRFTGRR 433

  Fly   617 ------WLWTG--LFNIVAGCIAYCGWLVPKPSVIGLDPNVALLMCSAMVSKMAISTTLSILTTC 673
                  :||||  |..::|.......|:|                ..||:.:..||.|.|::|..
  Fly   434 LTTMFLFLWTGVSLLLVLAVPAGSTTWIV----------------AFAMLGRFGISATYSVVTLY 482

  Fly   674 TVELVSDDKKKITSFSTICWARFWLLGAPFIGSTV-VFGQLIPQTAFASLAILGGLCTSLISSPR 737
            |.||.....:.....:...:|....:.||::...: ..|..||.|......::.||.|..:....
  Fly   483 TAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICGCCVLVAGLLTLTLPETG 547

  Fly   738 THPISRPSSPAAQGT 752
            |..:|.....:|..|
  Fly   548 TGKLSDKVESSASST 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	127/573 (22%)
CG44098	NP_001262264.1	MFS	353..733	CDD:119392	94/419 (22%)
CG6356	NP_651240.1	MFS	167..544	CDD:119392	93/415 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458318
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950