Protein Alignment CG44098 and slc22a2

DIOPT Version :9

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_998315.1
• Gene: slc22a2 / 406424
• ZFINID: ZDB-GENE-040426-2167
• Length: 562
• Species: Danio rerio
• Alignment Length: 597
• Identity: 136/597 - (22%)
• Similarity: 244/597 - (40%)
• Gaps: 84/597 - (14%)

  Fly   204 TKVDAVGQITGPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQTQ 268
            |..:.:.:..|.:|:.|:|......|..||.|:....|:|....|.|   :|:.|.....:.:..
Zfish     2 TTFEEILEEAGTFGRSQIRIFCTFCLVSIPFSFVYVGIVFQGFTPEH---WCRDPGVSEIRERCG 63

  Fly   269 W---------IKVSHPQKEESDDQ--EFSIDFCNVYQDAQEHAHHYYNYENSDQEPRVWEKPLHR 322
            |         :.:.:.....|..|  .|.:|: |....:.|:....:|.......|
Zfish    64 WSLQDARRATVPLINGSSGASYSQCGRFDVDW-NATGLSCENPDGDFNQSQLSVMP--------- 118

  Fly   323 NSNVIPCTEFQHESDY---HSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLL-KYFSPR 383
               ::.|.: ..|.||   .|.||::||||.....|.:.|.....|.|.|.|....|. ||...:
Zfish   119 ---MMSCVD-GWEYDYVGRQSFVTEFDLVCGDAWYVDMFQATLSIGFLVGSIAIGYLADKYGRMK 179

  Fly   384 NVMLFGMITQIFCGNLTGHVA----SYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVS 444
            :.::    |..|.| :||.:.    :|...:.||.|........:..|..::.::.|..:|..|.
Zfish   180 SFLM----TNFFIG-VTGILVATSPNYISLLVFRALFGFGVKGGWMVGYVLITELVGVDHRRTVG 239

  Fly   445 TLFEQFWSIGVMMLPGVASFWSSWSHLYMAISWPTV-ILIYLWQWIPDSPRWLIARGRTQDAKKI 508
            ..::.|:|:|:::||.:|.|.::|..|.:..:.|.: .|.|.| :||:|||||:.:.:..:|.:|
Zfish   240 VTYQLFFSMGILLLPLLAYFITNWRWLQVVFTVPYICFLTYYW-FIPESPRWLLTQNKIAEAVEI 303

  Fly   509 LLECVEVNGTGYNLPHDIDQQLELQAQTAMDAPPPSGWWSMWKGERAVRHIVCVHLAWSLYIVVY 573
            .....:.|      ...:.:::|......:|:...:.:..::|..:...:...:...|....|||
Zfish   304 TKSIAKEN------RKTLSKKIETLKDDNIDSGSTASFMDLFKTAKLRTYTFILSFNWFTSAVVY 362

  Fly   574 YGMLLNIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIAYCGWLVP 638
            .|:::.: .....::|::...:|..|:...|..|..|.:..|: |.....|||||........:|
Zfish   363 QGLIMRL-GILGGNVYVDFLISGIVELPAAFLILLTIERIGRR-LPFATANIVAGAACLITAFIP 425

  Fly   639 KPSVIGLDPNVALLMCSAMVSKMAISTTLSILTTCTVELVSDDKKK--ITSFSTICWARFWLLG- 700
                   |....|....|.|.::.|:....::.....||.....:.  ::..||:|     .:|
Zfish   426 -------DSMFWLKSAVACVGRLGITMAFEMVVFVNTELYPTVIRNLGVSVCSTLC-----DVGG 478

  Fly   701 --APFI--GSTVVFGQLIPQTAFASLA-ILGGLC-----TSLISSPRT-----HPISRPSSP-AA 749
              |||:  ...|::.:| |...|.:|| :.|||.     |..:..|.|     ||.....:| .:
Zfish   479 IVAPFLLYRLAVIWLEL-PLIIFGALAFVAGGLVLLLPETKGVPLPETIDDIEHPNRNKENPQQS 542

  Fly   750 QGTQNI-TSQFT 760
            |..:|: ||..|
Zfish   543 QQLENLMTSDVT 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	124/548 (23%)
		MFS	353..733	CDD:119392	91/398 (23%)
slc22a2	NP_998315.1	2A0119	12..525	CDD:273328	126/556 (23%)
		MFS	146..515	CDD:119392	90/395 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588694
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840