Protein Alignment CG44098 and slc22a4

DIOPT Version :9

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_957143.1
• Gene: slc22a4 / 393822
• ZFINID: ZDB-GENE-040426-1517
• Length: 553
• Species: Danio rerio
• Alignment Length: 584
• Identity: 134/584 - (22%)
• Similarity: 221/584 - (37%)
• Gaps: 81/584 - (13%)

  Fly   207 DAVGQITGPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQTQWIK 271
            |.:....|.||.:||...|.:.:..:|:.:....|:|....|.|.   |..|..|..  .:.|..
Zfish     5 DDITSFLGTWGPFQLTVFLALAISILPNGFVGLYIVFVGDTPAHE---CLIPEQINI--SSVWRD 64

  Fly   272 VSHPQKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENSDQEPRVWEKPLHRNSNVI---PCTE-- 331
            .:.|  .:..|.......|:.|:..........||     .|.|     ..|.:.|   ||.:
Zfish    65 AAIP--TQMQDGVLKRSSCSRYRLDTLRQLSMLNY-----TPNV-----EVNLSQIETEPCVDGW 117

  Fly   332 -FQHESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFGM----- 390
             :..|....::||::||||.|:....:|...:..|||.|..|:.|:...:..|.| ||.|
Zfish   118 SYSQEFYQSTIVTEWDLVCEREYKGPLTSSIYFCGVLVGTFLSGQMSDRYGRRPV-LFTMMALQT 181

  Fly   391 ---ITQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVSTLFEQFWS 452
               :.|:|..:.....|.| ..|.|...|....|  |..|.:|::..:    |....:|.....|
Zfish   182 ITILIQMFSPSWEVFSAIY-FFVGFSGFSNYVVA--YVLGSEILSPAS----RVLFGSLGVFMGS 239

  Fly   453 -IGVMMLPGVASFWSSWSHLYMAISWPTVILIYLWQWIPDSPRWLIARGRTQDAKKILLECVEVN 516
             ||.|..|..|.|..||..|.:..:...::...||.:||:|||||:::|||.:|:.:|....|.|
Zfish   240 GIGQMFFPLAAYFIRSWRWLVLTNALTGLLYFPLWWFIPESPRWLLSQGRTAEAEAVLRRAAEKN 304

  Fly   517 GTGYNLPHDIDQQLE--------LQAQTAMDAPPPSGWWSMWKGERAVRHIVCVHLAWSLYIVVY 573
            ..  ..|..|....|        :|..:.:|         :.....||..|:...|.|.:..:.|
Zfish   305 RV--TAPEVIFSSSEIEEAAKKRIQKHSILD---------ILSNCNAVSTILICSLLWMVITMSY 358

  Fly   574 YGMLLNIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIAYCGWLVP 638
            |.::||..:. ..:.|:|.|.:...|:........|:...:|:....... ::.|.:.:...|:|
Zfish   359 YALILNTTNL-HGNPYLNFFLSAVVEVPAYIIAALLLRFCSRRICQASTL-LLGGALIFIIQLIP 421

  Fly   639 KPSVIGLDPNVALLMCSAMVSKMAISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLLGAPF 703
            ...       ..|.....|:.|:.::....::...|.||.....:.:...|....||...:.:||
Zfish   422 TEL-------QGLATALEMLGKLCVTAAFCVVYAVTSELFPTVVRNMAMGSCSMTARIGSIISPF 479

  Fly   704 IGSTVVFGQLIPQTAFASLAILGGLCTSLISS------PRT-------HPISRPSSPAAQGTQN 754
            |.....:.:.||......||:..|:.:.|:..      |.|       ..:.|...|.|..|::
Zfish   480 IIYLGNYYRYIPYIVIGGLALFSGVMSLLLPESKGKVLPETIAQMQSVRGLRRCRKPPAASTED 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	126/538 (23%)
		MFS	353..733	CDD:119392	91/396 (23%)
slc22a4	NP_957143.1	2A0119	12..520	CDD:273328	128/552 (23%)
		MFS	144..510	CDD:119392	92/393 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588457
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840