DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44098 and slc22a7b.1

DIOPT Version :9

Sequence 1:	NP_001262264.1	Gene:	CG44098 / 40590	FlyBaseID:	FBgn0264907	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	XP_021322800.1	Gene:	slc22a7b.1 / 393320	ZFINID:	ZDB-GENE-040426-1311	Length:	560	Species:	Danio rerio

Alignment Length:	563	Identity:	124/563 - (22%)
Similarity:	220/563 - (39%)	Gaps:	69/563 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 KVDAVGQITGPWGKWQLRTVLLIFLCK--IPSSWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQT 267
            |.|.:...|..:|::|:..|:|:|:.:  ||..:.:...|...|: .|.:........:|...|.
Zfish    12 KFDNILDETDGFGRYQIALVMLLFIPRITIPCHFLLNNFIAAIPS-HHCDISSLDADGLGNLTQK 75

  Fly   268 QWIKVSHPQKEESDDQEFSIDFCNVYQDAQEHAHHYY----NYENSDQEPRVWEKPLHRNSNVIP 328
            :.:.||.|.:|:.....     |:::      ||..:    |..:|...|            |:.
Zfish    76 ERLIVSVPAQEDGTPAS-----CHMF------AHPQFQLLINSSSSSALP------------VVE 117

  Fly   329 CT---EFQHESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFGM 390
            |.   .|.:.:...::.||:||||.:..|...:......||:.|.:....|...:..|:::|...
Zfish   118 CQNGWHFDNSTFISTLATQFDLVCDKRGLAKASATIFFVGVMCGAVFFGVLCDKYGRRSMLLVSY 182

  Fly   391 ITQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVSTLFEQFWSIGV 455
            :..|.....:...:||.:...||.|:.:....:......:..:....|:||.:.......||||.
Zfish   183 VFSIVFSVTSAFSSSYIMFAAFRFLTGLALTGISNISVVLSIEWVDTKHRTFMGLFGSMSWSIGN 247

  Fly   456 MMLPGVASFWSSWSHLYMAISWPTVILIYLWQWIPDSPRWLIARGRTQDAKKILLECVEVNGTGY 520
            |:|.|.|...:.|..|.:.::.|..:....|.|||||.|||||.|:|:.|.|.|.:|..     :
Zfish   248 MLLAGFAFMVTDWRLLIVIVTAPLFLATATWWWIPDSARWLIANGKTETAYKYLHKCAT-----F 307

  Fly   521 NLPHDIDQQLELQAQTAMDAPPPSG----WWSMWKGERAVRHIVCVHLAWSLYIVVYYGMLLNIR 581
            |...|...:::.:..:.:......|    :..:.|..:..:..:...:.|......|||:.|||.
Zfish   308 NQRLDFTSRVKPETLSTVVTVDHRGHSYTYLDLVKTPQLRKLTLFTGIVWYGVASTYYGISLNIT 372

  Fly   582 SFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCI--------AYCGWLVP 638
            .|..|. |:..|.....|:.......|.:.|..|:...||...:...||        .|  |..
Zfish   373 GFGLDP-YLTHFIYAAIEVPAKILVYFSLNKVGRRNTQTGTLVLTGFCILINIITPTEY--WTF- 433

  Fly   639 KPSVIGLDPNVALLMCSAMVSKMAISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLLGAPF 703
                     ...:.:....:|:.:.:|.:...|.....::..:....|:|    .||.....:|.
Zfish   434 ---------RTVIAVLGKGLSEASFTTVILYTTELYPTVMRQNGLGFTNF----MARMGASISPL 485

  Fly   704 IGSTVVFGQLIPQTAFASLAILGGLCTSLISSPRTHPISRPSS 746
            |.......:|:|:..|.|:||..|:...|:  |.|:..|.|.:
Zfish   486 IMLLEDIWKLLPEVIFCSMAIFCGIIALLL--PETNNASLPET 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	116/536 (22%)
CG44098	NP_001262264.1	MFS	353..733	CDD:119392	85/391 (22%)
slc22a7b.1	XP_021322800.1	Sugar_tr	22..526	CDD:331684	121/551 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588712
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840