DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG44098 and CG42269

DIOPT Version :9

Sequence 1:	NP_001262264.1	Gene:	CG44098 / 40590	FlyBaseID:	FBgn0264907	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_648019.2	Gene:	CG42269 / 38689	FlyBaseID:	FBgn0259164	Length:	662	Species:	Drosophila melanogaster

Alignment Length:	573	Identity:	123/573 - (21%)
Similarity:	229/573 - (39%)	Gaps:	92/573 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   207 DAVGQITGPWGKWQLRTVLLIFLCKIPSSWFMACI----IFTAPAPRHGEFFCKPPHTIGAQNQT 267
            |.:..:.|.:|::|    .|:|:|.||.|:|:|.:    ||....|.  :.:|..|...|...:.
  Fly    73 DDILPLIGEFGRYQ----KLLFICMIPFSFFVAFVYFSQIFLTLIPE--QHWCHVPELDGLDVEA 131

  Fly   268 QWIKVSHPQKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENSDQEPRVWEKPLHRNSNVIPCTEF 332
            : :.:|.|....        ::.|.|.       :..||.:...:.:|...|..      |..:.
  Fly   132 R-LALSIPMTNG--------EYNNCYM-------YDVNYTDILAQGKVMADPKW------PQVKC 174

  Fly   333 QH-------ESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFGM 390
            :|       |..|.:|.|:.:.||....|.:..|.....|.:.||:|...:...|.....::...
  Fly   175 RHGWSYNFTEIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTN 239

  Fly   391 ITQIFCGNLTGHVASYELHVFFRCLSAV----CCAQMYTAGGQIMADITGGKYRTCVSTL-FEQF 450
            :..:..|..|..|:::......|.....    |...||.    ::.:..|.||||.|:.: ...|
  Fly   240 MMGLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYI----LVLEYVGPKYRTFVANMSIAIF 300

  Fly   451 WSIGVMMLPGVASFWSSWSHLYMAISWPTVILIYLWQWIPDSPRWLIARGRTQDAKKIL--LECV 513
            ::....:||.:|.|.:.|..|.:..|.|.::.|:....:|:|.|||:::|:...|..||  ||
  Fly   301 FTGAACLLPWIAYFLADWKLLAIVTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLE-- 363

  Fly   514 EVNGTGYNLPHDIDQQLELQAQTAMDAPPPSGWWS---MWKGERAVRHIVCVHLAWSLYIVVYYG 575
              .|.|..:|....|......:...:....:|.:|   ::|..|..|..:.:.:.|....:|:.|
  Fly   364 --KGNGRQVPPQTYQIFTDSCKRMQEQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDG 426

  Fly   576 MLLNIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWL------WTGLFNIVAGCIAYCG 634
            .:.|:.|...| ::.....|.|:|:........::.:..|:||      .:|:|:::|
  Fly   427 HVRNVGSLGLD-IFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLA------- 483

  Fly   635 WLVPKPSVIGLDPNVALLMCSAMVSKMAISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLL 699
            .:||    :|: .:.||    |::.:..::.:.:|......|::.      |.......|...::
  Fly   484 TVVP----VGI-YSAAL----AIMGRFFVNISYNIGLQWAAEVLP------TVVRAQAVAFIHIM 533

  Fly   700 G------APFIGSTVVFGQLIPQTAFASLAILGGLCTSLISSPRTHPISRPSS 746
            |      |||:.......|.:|......|.|:|||...|:.....|.:.:..|
  Fly   534 GYVASIIAPFVVYLANISQALPLIILGILGIIGGLLALLLPETLNHVLPQTLS 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	119/548 (22%)
CG44098	NP_001262264.1	MFS	353..733	CDD:119392	86/401 (21%)
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	112/530 (21%)
CG42269	NP_648019.2	MFS	206..545	CDD:119392	78/369 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458351
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940