Protein Alignment CG44098 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: XP_038941497.1
• Gene: Slc22a12 / 365398
• RGDID: 621628
• Length: 578
• Species: Rattus norvegicus
• Alignment Length: 621
• Identity: 128/621 - (20%)
• Similarity: 221/621 - (35%)
• Gaps: 149/621 - (23%)

  Fly   214 GPWGKWQ-LRTVLLIFLCKIPSSWFMACII---FTAPAPRHGEFFCKPPHTIGAQNQTQ------ 268
            |..|::| |:.|.|:    .|..|.....:   |:|..|.|.   |..|....:.:|..
  Rat    11 GGRGRFQLLQAVALV----TPILWVTTQNMLENFSAAVPHHR---CWVPLLDNSTSQASIPGDFG 68

  Fly   269 ---WIKVSHPQKEESDDQEFSIDFCNVYQDAQ----EHAHHYYNYENSDQEPRVWEKPLHRNSNV 326
               .:.||.|...:....:     |..::..|    |......|:.::|.|
  Rat    69 RDVLLAVSIPPGPDQRPHQ-----CLRFRQPQWQLIESNTTATNWSDADTE-------------- 114

  Fly   327 IPCTE---FQHESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLF 388
             ||.:   :.|.:...::||.:||||....|..:.|...|.|:|.|..:.......|..|.|:.:
  Rat   115 -PCEDGWVYDHSTFRSTIVTTWDLVCDSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTW 178

  Fly   389 GMITQIFCGNLTGHVASYELHVFFRCL--SAVCCAQMYTAG--------GQ-------------- 429
            ..:.....|.:...:.::.|:..||.|  |||....|.||.        |:
  Rat   179 SYLLVSVSGTIAALMPTFPLYCLFRFLVASAVAGVMMNTASLCMFPVVLGREGYMQDPELTPSLL 243

  Fly   430 -IMADITGGKYRTCVSTLFEQFWSIGVMMLPGVASFWSSWSHLYMAISWP-TVILIYLWQWIPDS 492
             .:.:.|..:....:.||....:|.|.::...||....||..|.:|:|.| .:..:|.| |:|:|
  Rat   244 LAVMEWTSAQAGPLMMTLNALGFSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSW-WLPES 307

  Fly   493 PRWLIARGRTQDAKKILLECVEVNGTGYNLPHDIDQQLELQAQT--------AMDAPPPSGWWSM 549
            .||||..||...:.:.|.....||            :.:.:|.|        ||...|
  Rat   308 ARWLITVGRLDQSLRELQRVAAVN------------RRKAEADTLTVEVLRSAMQEEP------- 353

  Fly   550 WKGERA--------------VRHIVCVHLAWSLYIVVYYGMLLNIRSFSRDHLYINTFFAGFSEM 600
             .|.:|              :|..:.: |.|..:...:||:.|::::.. .::::.....|..::
  Rat   354 -NGNQAGARLGTLLHTPGLRLRTFISM-LCWFAFGFTFYGLALDLQALG-SNIFLLQALIGIVDL 415

  Fly   601 MGTFFGLFLILKTTRKWLWTGLFNIVAGCIAYCGWLVPKP--------SVIGLDPNVALLMCSAM 657
            ......|.|:.:..|: |......::.|.......|||:.        :|:||....|...|..:
  Rat   416 PVKMGSLLLLSRLGRR-LCQASSLVLPGLCILANILVPREMGILRSSLAVLGLGSLGAAFTCVTI 479

  Fly   658 VSKMAISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLLGAPFIGSTVVFGQLIPQTAFASL 722
            .|.....|.:. :|...:..|:              ||...:..|.:....|:|..:|...:..:
  Rat   480 FSSELFPTVIR-MTAVGLGQVA--------------ARGGAMLGPLVRLLGVYGSWLPLLVYGVV 529

  Fly   723 AILGGLCTSLISSPRTHPISRPSSPAAQGTQNITSQ 758
            .:|.||...|:  |.|..:..|.:     .|:|..|
  Rat   530 PVLSGLAALLL--PETKNLPLPDT-----IQDIQKQ 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	121/591 (20%)
		MFS	353..733	CDD:119392	88/435 (20%)
Slc22a12	XP_038941497.1	MFS_OAT	109..541	CDD:340932	100/487 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346822
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930