DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44098 and T22F7.1

DIOPT Version :9

Sequence 1:	NP_001262264.1	Gene:	CG44098 / 40590	FlyBaseID:	FBgn0264907	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_497209.1	Gene:	T22F7.1 / 3564822	WormBaseID:	WBGene00020701	Length:	510	Species:	Caenorhabditis elegans

Alignment Length:	543	Identity:	101/543 - (18%)
Similarity:	193/543 - (35%)	Gaps:	122/543 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 IKVSHPQKEE------SDDQEFSIDFCNVYQDAQEHAHHYYNY-----ENSDQE----------- 312
            :|.|..::||      ...........:.|.|.:||.....||     |...|:
Worm     1 MKASEEEEEEVVHSGGGYTSPLMSSLSDAYDDGEEHQKKKKNYGLVQVEEGGQDVISSVEELLKA 65

  Fly   313 PRVWEKP--------------LHRNSNVIP---------CTEFQHESDYHSVVTQYDLVCSRDIL 354
            ...| :|              |...|.:.|         |||   ...::::..:::|. |:..|
Worm    66 TTAW-RPYPLFIICSMSFLWSLCALSAISPAFTAPAGDECTE---NCSFYTIQNEFNLT-SKFFL 125

  Fly   355 VS----VTQFFHLFGVLTGGILANQLLKYFSPRNVMLFGMITQIFCGNLTGHVASYELHVFFRCL 415
            |.    .|..:.|..:|.|.:.| .:...|..|.:::..::.....|:|.....::.|.:..|.:
Worm   126 VEPAELTTSIYFLGNLLIGQLFA-VVADRFGRRPIIIICLLLTGIVGSLGSLAPNFPLLLVARFI 189

  Fly   416 SAVCCAQMYTAGGQIMADITGGKYRTCVSTLFEQFWSIGVMMLPGVASFWSSWSHLYMAISWPTV 480
            ...|...:.|....:..:....:.::..|..|...|..|...|..::.::::|..|.:|.:.|.:
Worm   190 QGSCYTPLTTVNYVLSGESIPHRSQSLTSIFFGVSWVCGYCFLAPLSVWFNTWRSLQLATALPNI 254

  Fly   481 IL-IYLWQWIPDSPRWLIARGRTQDAKK-----ILLECVEVNGTGYNLPHDIDQQLELQAQTA-M 538
            :: ::|...:|:|..:.|.:...:..:|     .||.|.::|       :|:|..:|...:.| .
Worm   255 LVAVFLMGTLPESVGYSIEKKNRKAVQKWIKRNELLSCKKLN-------YDLDMIMEKTEKIATS 312

  Fly   539 DAPPPSGWWSMWKGERAV-------RHIVCVHLAWSLYIVVYYGMLLNIRSFSRDHLYINTFFAG 596
            .:|.|....::::..|.:       |.|:.....|.|..:.|..:.|...|.......::..|:|
Worm   313 SSPTPQNRLTIFEMIREILSDREITRRIIVETFLWILTFMTYCALSLTSTSVGNSDPLVSFLFSG 377

  Fly   597 FSEMMGTFFGLFLILKTTR---KWL--WTGLFNIVAGCIAYCGWLVPKPSVIGLDPNVALLMCSA 656
            ..|:....|....:.:|.|   ::|  :||...::              ::..|..:.:|.:...
Worm   378 VVELPAYLFIPICLTRTKRRPTRFLCHFTGSMALL--------------TMYFLSNDTSLHLIIW 428

  Fly   657 MVSKMAISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLLG------------APFIGSTVV 709
            :|:|...|...........||          |.|  |.|...:|            ||.|   .:
Worm   429 LVAKFCASCCYIFCFIYAAEL----------FPT--WCRSCCIGVCSTCCNIGAIVAPHI---FL 478

  Fly   710 FGQLIPQTAFASLAILGGLCTSL 732
            .....|...|..||.:|.||:.|
Worm   479 IDSAAPGAQFLVLAAVGLLCSGL 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	99/539 (18%)
CG44098	NP_001262264.1	MFS	353..733	CDD:119392	79/415 (19%)
T22F7.1	NP_497209.1	MFS_SLC22	101..505	CDD:340875	84/442 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162986
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840