DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG44098 and Slc22a14

DIOPT Version :9

Sequence 1:	NP_001262264.1	Gene:	CG44098 / 40590	FlyBaseID:	FBgn0264907	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_001101663.2	Gene:	Slc22a14 / 316061	RGDID:	1306470	Length:	630	Species:	Rattus norvegicus

Alignment Length:	706	Identity:	154/706 - (21%)
Similarity:	273/706 - (38%)	Gaps:	126/706 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 EANNNNSTSSNHNHNPNHIRTHRRQHEYQLYPNDTFA------QLEGKAPKPNTKMQTKVDAVGQ 211
            |..|:|:...:.:...:|      :||.. ||:..::      :|:....:.:.|..:.:.|:|:
  Rat     3 EEQNSNTEFGSQDSRDSH------RHELS-YPSQNWSLEMLLRRLKALDDRRDDKFASVLGAIGE 60

  Fly   212 ITGPWGKWQLRTVLLIFLCKIPSSWFMAC--IIFTAPAPRHGEFFCKPPHTIGAQNQTQWIKVSH 274
                :|.:|.|.|.|.|:..|.|::|:..  .:.||..|     :|          .|.||....
  Rat    61 ----FGTFQWRLVALTFIPSILSTFFLLSHHFLLTAQRP-----YC----------NTSWILQVG 106

  Fly   275 PQKEESDDQEFSID--------FCNVY----QDAQEHAHHYYNYENSDQEPRVWEKPLHRNSNVI 327
            |...|.:....::.        .|.:|    .|.....|...||..:.:..  |..|
  Rat   107 PNLTEDEQLNLTVPRAPNGSFLTCLMYIPVPWDLDSIVHFGLNYTETCKHG--WIYP-------- 161

  Fly   328 PCTEFQHESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTG----GILANQLLKYFSPRNVMLF 388
                |.|.   .|:..::||||..:......|...|.|:|||    |.|:::|.:|    .::|.
  Rat   162 ----FAHT---RSLTNEFDLVCGNEPHEENGQTVFLSGILTGSLLFGFLSDKLGRY----PIILL 215

  Fly   389 GMITQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVSTLFEQFWSI 453
            .::..:..|..|..|.|:..::|||...|............::.:...|::|.....|...|::|
  Rat   216 SLLGILIFGFGTAFVNSFYQYLFFRFFVAQASVGYAICSVSLVMEWLVGEHRAQAIILQHCFFTI 280

  Fly   454 GVMMLPGVASFWSSWSHLYMAISWPTVILI-YLWQWIPDSPRWLIARGRTQDAKKILLECVEVNG 517
            ||::|.|.|...:.|..|::....|...|| .:|. :.:|||||:.:|:.::|||:|....|||.
  Rat   281 GVILLTGFAYKINHWRLLFLLGGVPMFPLICNIWV-LQESPRWLMVKGKVEEAKKVLCYAAEVNK 344

  Fly   518 TGYNLPHDIDQQLELQAQTAMDAPPPSGWWSMWKGERAVRHIVCVHLAWSLYIVVYYGMLLNIRS 582
            .  .:|.::..:|:|..:.|     .:.....:..:...:.::.:...|.....|...:.|.::.
  Rat   345 K--TIPLNLLNELQLPGKKA-----KASILDFYTNQHLFKVVLAMGCVWFTVSYVSLTLSLKMKD 402

  Fly   583 FSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIAY-CGWLVPKPSVIGLD 646
            |..| :|........:.:......:.|:....|||    ..|:....:.: |..|:..|..:
  Rat   403 FGLD-IYFIQVVPCITAVPARLCCILLLEYFGRKW----SLNLTLSLVTFTCLSLLFVPEEL--- 459

  Fly   647 PNVALLMCSAMVSKMAISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLLGAPFIGSTVVFG 711
            .:..:||  .::.:.:::.|:||....|.||:....:. |....:..|  |..||  |.|..:|.
  Rat   460 KSTTILM--LVLGEFSMAGTVSIFFIYTAELLPTILRS-TGLGMVSIA--WTAGA--ISSLAIFK 517

  Fly   712 QLIPQTA--FASLAILGGLC-TSLISSPRTHPI-------SRPSSPAAQGTQNITSQFTIIDGM- 765
            |...|..  |..|..:..|| :||:......|:       ||.|......:::.:......:.|
  Rat   518 QTKTQLPIFFCCLCCILALCFSSLVPETGNQPLRDSIEYCSRDSLEHKDKSKDSSKVLMAEESMC 582

  Fly   766 DNKGYSPTSKTIHSNSTILK----------LNTPQSNLPPQLMPGIWTTKITEDGP 811
            |....|..:|....|:..||          |..|....|.||         .||.|
  Rat   583 DVAADSVLTKNTMFNAMTLKSETDSFLNMALEVPNRESPVQL---------PEDHP 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	121/538 (22%)
CG44098	NP_001262264.1	MFS	353..733	CDD:119392	89/388 (23%)
Slc22a14	NP_001101663.2	MFS	147..527	CDD:421695	95/423 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010