Protein Alignment CG44098 and Slc22a14

DIOPT Version :10

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_001101663.2
• Gene: Slc22a14 / 316061
• RGDID: 1306470
• Length: 630
• Species: Rattus norvegicus
• Alignment Length: 706
• Identity: 154/706 - (21%)
• Similarity: 273/706 - (38%)
• Gaps: 126/706 - (17%)

  Fly   153 EANNNNSTSSNHNHNPNHIRTHRRQHEYQLYPNDTFA------QLEGKAPKPNTKMQTKVDAVGQ 211
            |..|:|:...:.:...:|      :||.. ||:..::      :|:....:.:.|..:.:.|:|:
  Rat     3 EEQNSNTEFGSQDSRDSH------RHELS-YPSQNWSLEMLLRRLKALDDRRDDKFASVLGAIGE 60

  Fly   212 ITGPWGKWQLRTVLLIFLCKIPSSWFMAC--IIFTAPAPRHGEFFCKPPHTIGAQNQTQWIKVSH 274
                :|.:|.|.|.|.|:..|.|::|:..  .:.||..|     :|          .|.||....
  Rat    61 ----FGTFQWRLVALTFIPSILSTFFLLSHHFLLTAQRP-----YC----------NTSWILQVG 106

  Fly   275 PQKEESDDQEFSID--------FCNVY----QDAQEHAHHYYNYENSDQEPRVWEKPLHRNSNVI 327
            |...|.:....::.        .|.:|    .|.....|...||..:.:..  |..|
  Rat   107 PNLTEDEQLNLTVPRAPNGSFLTCLMYIPVPWDLDSIVHFGLNYTETCKHG--WIYP-------- 161

  Fly   328 PCTEFQHESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTG----GILANQLLKYFSPRNVMLF 388
                |.|.   .|:..::||||..:......|...|.|:|||    |.|:::|.:|    .::|.
  Rat   162 ----FAHT---RSLTNEFDLVCGNEPHEENGQTVFLSGILTGSLLFGFLSDKLGRY----PIILL 215

  Fly   389 GMITQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVSTLFEQFWSI 453
            .::..:..|..|..|.|:..::|||...|............::.:...|::|.....|...|::|
  Rat   216 SLLGILIFGFGTAFVNSFYQYLFFRFFVAQASVGYAICSVSLVMEWLVGEHRAQAIILQHCFFTI 280

  Fly   454 GVMMLPGVASFWSSWSHLYMAISWPTVILI-YLWQWIPDSPRWLIARGRTQDAKKILLECVEVNG 517
            ||::|.|.|...:.|..|::....|...|| .:|. :.:|||||:.:|:.::|||:|....|||.
  Rat   281 GVILLTGFAYKINHWRLLFLLGGVPMFPLICNIWV-LQESPRWLMVKGKVEEAKKVLCYAAEVNK 344

  Fly   518 TGYNLPHDIDQQLELQAQTAMDAPPPSGWWSMWKGERAVRHIVCVHLAWSLYIVVYYGMLLNIRS 582
            .  .:|.::..:|:|..:.|     .:.....:..:...:.::.:...|.....|...:.|.::.
  Rat   345 K--TIPLNLLNELQLPGKKA-----KASILDFYTNQHLFKVVLAMGCVWFTVSYVSLTLSLKMKD 402

  Fly   583 FSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIAY-CGWLVPKPSVIGLD 646
            |..| :|........:.:......:.|:....|||    ..|:....:.: |..|:..|..:
  Rat   403 FGLD-IYFIQVVPCITAVPARLCCILLLEYFGRKW----SLNLTLSLVTFTCLSLLFVPEEL--- 459

  Fly   647 PNVALLMCSAMVSKMAISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLLGAPFIGSTVVFG 711
            .:..:||  .::.:.:::.|:||....|.||:....:. |....:..|  |..||  |.|..:|.
  Rat   460 KSTTILM--LVLGEFSMAGTVSIFFIYTAELLPTILRS-TGLGMVSIA--WTAGA--ISSLAIFK 517

  Fly   712 QLIPQTA--FASLAILGGLC-TSLISSPRTHPI-------SRPSSPAAQGTQNITSQFTIIDGM- 765
            |...|..  |..|..:..|| :||:......|:       ||.|......:::.:......:.|
  Rat   518 QTKTQLPIFFCCLCCILALCFSSLVPETGNQPLRDSIEYCSRDSLEHKDKSKDSSKVLMAEESMC 582

  Fly   766 DNKGYSPTSKTIHSNSTILK----------LNTPQSNLPPQLMPGIWTTKITEDGP 811
            |....|..:|....|:..||          |..|....|.||         .||.|
  Rat   583 DVAADSVLTKNTMFNAMTLKSETDSFLNMALEVPNRESPVQL---------PEDHP 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	MFS_SLC22	329..732	CDD:340875	95/411 (23%)
Slc22a14	NP_001101663.2	MFS	147..527	CDD:475125	95/423 (22%)