Protein Alignment CG44098 and Slc22a6

DIOPT Version :10

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_058920.1
• Gene: Slc22a6 / 29509
• RGDID: 69338
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 624
• Identity: 128/624 - (20%)
• Similarity: 232/624 - (37%)
• Gaps: 119/624 - (19%)

  Fly   207 DAVGQITGPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQ---TQ 268
            |.:.|:.|. |::||..|.::....:..:.......|||..|.|   .|:||........   ..
  Rat     5 DLLKQVGGV-GRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPPH---HCRPPANANLSKDGGLEA 65

  Fly   269 WIKVSHPQKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENSDQEPRVWEKPLHRNSN------VI 327
            |:.:....:.||         |..:...|                  |..|.:..:.      ..
  Rat    66 WLPLDKQGQPES---------CLRFTSPQ------------------WGPPFYNGTEANGTRVTE 103

  Fly   328 PCTE---FQHESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFG 389
            ||.:   :.:.:...::||:::||||......:.|..::.|||.|.::...|......|.|::..
  Rat   104 PCIDGWVYDNSTFPSTIVTEWNLVCSHRAFRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILN 168

  Fly   390 MITQIFCGNLTGHVASYELHVFFRCLSAVCCAQM----YTAGGQIMADITGGKYRTCVSTLFEQF 450
            .:.....|....:..:|.::..||.||.:..|.:    .|...:.|...|    |..|.||....
  Rat   169 YLQTAVSGTCAAYAPNYTVYCVFRLLSGMSLASIAINCMTLNVEWMPIHT----RAYVGTLIGYV 229

  Fly   451 WSIGVMMLPGVASFWSSWSHLYMAISWPTVI-LIYLWQWIPDSPRWLIARGRTQDAKKILLECVE 514
            :|:|..:|.|:|.....|.||.:.:|.|..| .||.|.:| :|.||..:.||.....:.|.....
  Rat   230 YSLGQFLLAGIAYAVPHWRHLQLVVSVPFFIAFIYSWFFI-ESARWYSSSGRLDLTLRALQRVAR 293

  Fly   515 VNG---TGYNLPHDIDQQLELQAQTAMDAPPPSGWWSMWKGERA---------VRHI-VCVHLAW 566
            :||   .|..|..:: .:..||.:..:.           ||:.:         :||: :|:.:.|
  Rat   294 INGKQEEGAKLSIEV-LRTSLQKELTLS-----------KGQASAMELLRCPTLRHLFLCLSMLW 346

  Fly   567 SLYIVVYYGMLLNIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAG-CI 630
            ......|||::::::.|......|...|....  :...|..||::.:..:........::|| ||
  Rat   347 FATSFAYYGLVMDLQGFGVSMYLIQVIFGAVD--LPAKFVCFLVINSMGRRPAQMASLLLAGICI 409

  Fly   631 AYCGWLVPKPSVIGLDPNVALLMCSAMVSKMAISTTLSILTTCTVELVSDDKKKITSFSTICWAR 695
            ...| ::||...|       :....|::.|..::::.:.:...|.||.....::.........||
  Rat   410 LVNG-IIPKSHTI-------IRTSLAVLGKGCLASSFNCIFLYTGELYPTVIRQTGLGMGSTMAR 466

  Fly   696 FWLLGAPFIGSTVVFGQLIPQTAFASLAILGGLCTSLISSPRTHPISRPSSPAAQGTQNITSQFT 760
            ...:.:|.:..|..|...:|...|.::.::....|:|:  |.|     ...|.....|::.|:
  Rat   467 VGSIVSPLVSMTAEFYPSMPLFIFGAVPVVASAVTALL--PET-----LGQPLPDTVQDLKSR-- 522

  Fly   761 IIDGMDNKGYSPTSKTIHSNSTILKLNTPQSNLPPQLMP 799
                  ::|               |.|..|.....|:||
  Rat   523 ------SRG---------------KQNQQQQEQQKQMMP 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	MFS_SLC22	329..732	CDD:340875	92/424 (22%)
Slc22a6	NP_058920.1	2A0119	11..515	CDD:273328	117/568 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	514..551		9/50 (18%)