Protein Alignment CG44098 and Slc22a3

DIOPT Version :9

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_062103.1
• Gene: Slc22a3 / 29504
• RGDID: 3701
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 555
• Identity: 137/555 - (24%)
• Similarity: 250/555 - (45%)
• Gaps: 65/555 - (11%)

  Fly   214 GPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQTQWIKVSHPQKE 278
            |.:|::|.|..||:.|..:..::....::|....|.:  ::|:.|.......:..|
  Rat    12 GEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGSQPDY--YWCRGPRATALAERCAW--------- 65

  Fly   279 ESDDQEFSIDFCNVYQDA----QEHAHHYYNYENSDQEPRVWEKPL----HRNSNVIPCT-EFQH 334
             |.::|:::....::..|    |.|.|.|. .|:::....:...||    :|::.::||: ::::
  Rat    66 -SPEEEWNLTTPELHVPAERRGQGHCHRYL-LEDTNTSSELSCDPLAAFPNRSAPLVPCSGDWRY 128

  Fly   335 ESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFGMITQIFCGNL 399
            ...:.::|:|:||||....::.:||.....|.|.|..    .|.|.:.|...|...:...|...:
  Rat   129 VETHSTIVSQFDLVCGNAWMLDLTQAILNLGFLAGAF----TLGYAADRYGRLIVYLISCFGVGI 189

  Fly   400 TGHVA----SYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVSTLFEQFWSIGVMMLPG 460
            ||.|.    ::.:.|.||.|..|.....:.....|:.:|.|.|.|..|..:.:.|:::|:::|||
  Rat   190 TGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPG 254

  Fly   461 VASFWSSWSHLYMAISWPT-VILIYLWQWIPDSPRWLIARGRTQDAKKILLECVEVNG----TGY 520
            :|.|..||..:.:|||.|: :.|:|.|. :|:||||||.|.:.:.|.:||....:.||    :.|
  Rat   255 IAYFTPSWQGIQLAISLPSFLFLLYYWV-VPESPRWLITRKQGEKALQILRRVAKCNGKHLSSNY 318

  Fly   521 NLPHDIDQQLELQAQTAMDAPPPSGWWSMWKGERAVRHIVCVHLAWSLYIVVYYGMLLNIRSFSR 585
            :.....|:  |:...:.:|         :.:..:..:..:.:..||....|||.|:::.: ....
  Rat   319 SEITVTDE--EVSNPSCLD---------LVRTPQMRKCTLILMFAWFTSAVVYQGLVMRL-GLIG 371

  Fly   586 DHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIAYCGWLVPKPSVIGLDPNVA 650
            .:||::.|.:|..|:.|....|..|.:..|: |.....|||||........:|: .:..|...||
  Rat   372 GNLYMDFFISGLVELPGALLILLTIERLGRR-LPFAASNIVAGVSCLVTAFLPE-GIPWLRTTVA 434

  Fly   651 LLMCSAMVSKMAISTTLSILTTCTVELVSDDKKK--ITSFSTICWARFWLLGAPFIGSTVVFGQL 713
            .|      .::.|:....|:.....||.....:.  ::..|.:|  .|..:.|||:...:....|
  Rat   435 TL------GRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLC--DFGGIIAPFLLFRLAAIWL 491

  Fly   714 -IPQTAFASLA-ILGGLCTSLISSPRTHPISRPSS 746
             :|...|..|| :.|||...|   |.|..|:.|.:
  Rat   492 ELPLIIFGILASVCGGLVMLL---PETKGIALPET 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	132/537 (25%)
		MFS	353..733	CDD:119392	101/392 (26%)
Slc22a3	NP_062103.1	2A0119	12..523	CDD:273328	137/553 (25%)
		MFS	145..513	CDD:119392	102/397 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347130
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840