Protein Alignment CG44098 and SLC22A24

DIOPT Version :10

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_001129978.2
• Gene: SLC22A24 / 283238
• HGNCID: 28542
• Length: 552
• Species: Homo sapiens
• Alignment Length: 647
• Identity: 133/647 - (20%)
• Similarity: 232/647 - (35%)
• Gaps: 170/647 - (26%)

  Fly   206 VDAVGQITGPWGKWQLRTVLLIFLCKIPSSWFMACII--FTAPAPRHGEFFCKPP---------H 259
            :|.||.:    |::|:  .|:.|.|......|...::  |||..|.|.   |..|         :
Human     7 LDQVGGM----GRFQI--CLIAFFCITNILLFPNIVLENFTAFTPSHR---CWVPLLDNDTVSDN 62

  Fly   260 TIGAQNQTQWIKVSHPQKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENSDQEPRVWEKPLHRNS 324
            ..|..::...:::|.|.......|:     |..:...|....|......:..||
Human    63 DTGTLSKDDLLRISIPLDSNLRPQK-----CQRFIHPQWQLLHLNGTFPNTNEP----------- 111

  Fly   325 NVIPCTE---FQHESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVM 386
            :..||.:   :...|...::||::||||....|.|:.|...:.|.|.||::...|    |.|
Human   112 DTEPCVDGWVYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHL----SDR--- 169

  Fly   387 LFGMITQIFCGNLTGHVASYELHVFFRCLS-----AVCCAQMYTAGGQIMADITGGKY------- 439
               :..:|.|     .:...:|.:...|.:     .|.|...:.||...|. |.|..:
Human   170 ---VGRKIIC-----KLCFLQLAISNTCAAFAPTFLVYCILRFLAGFSTMT-ILGNTFILSLEWT 225

  Fly   440 ----RTCVSTLFEQFWSIGVMMLPGVASFWSSWSHLYMAISWPTVILIYLWQW-IPDSPRWLIAR 499
                |:....:....:|:|.|:|.|:|.....|..|.:.:|.| :|:::|..| :.:|.||||..
Human   226 LPRSRSMTIMVLLCSYSVGQMLLGGLAFAIQDWHILQLTVSTP-IIVLFLSSWKMVESARWLIIN 289

  Fly   500 GRTQDAKKILLECVEVNGTGYNLPHDIDQQL-------ELQA---QTAMDAPPPSGWWSMWKGER 554
            .:..:..|.|.....:||. .|....:..:|       ||.|   :|::        :|:::..:
Human   290 NQLDEGLKELRRVAHINGK-KNTEETLTTELVRSTMKKELDAVRIKTSI--------FSLFRAPK 345

  Fly   555 AVRHIVCVHLAWSLYIVVYYGMLLNIRSFSRDHLYIN-----------TFFA------------- 595
            ....:..:........|.:||::||::     ||..|           ||.|
Human   346 LRMRVFGLCFVRFAITVPFYGLILNLQ-----HLGSNVSLFQILCGAVTFTARCVSLLTLNHMGR 405

  Fly   596 GFSEMMGTF-FGLFLILKTTRKWLWTGLFNIVAGCIAYCGWLVPKPSVIGLDPNVALLMCSAMVS 659
            ..|:::.|| .|||:::.|    .......|:...:|..|        ||   :|:....||.|.
Human   406 RISQILFTFPVGLFILVNT----FLPQEMQILRVVLATLG--------IG---SVSAASNSASVH 455

  Fly   660 KMAISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLLGAPFIGSTVVFGQLIPQTAFASLAI 724
            ...:..|:...|...:..||              .|.....||.:.:.:.:...:|..::....|
Human   456 HNELVPTILRSTVAGINAVS--------------GRTGAALAPLLMTLMAYSPHLPWISYGVFPI 506

  Fly   725 LGGLCTSLISSPRTHPISRPSSPAAQGTQNITSQFTIIDGMDNKGYSPTSKTIHSNSTILKL 786
            |.  ...::..|.|..:..|::  .|..:|           |.|    .|:.|....|.:|:
Human   507 LA--VPVILLLPETRDLPLPNT--IQDVEN-----------DRK----DSRNIKQEDTCMKV 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	MFS_SLC22	329..732	CDD:340875	96/457 (21%)
SLC22A24	NP_001129978.2	MFS_OAT	109..516	CDD:340932	99/479 (21%)