Protein Alignment CG44098 and Slc22a22

DIOPT Version :10

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: XP_036015188.1
• Gene: Slc22a22 / 210463
• MGIID: 2446114
• Length: 587
• Species: Mus musculus
• Alignment Length: 613
• Identity: 128/613 - (20%)
• Similarity: 208/613 - (33%)
• Gaps: 162/613 - (26%)

  Fly   207 DAVGQITGPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQTQWI- 270
            |.:....|..|::|:..::|:.:..:..|.......|||..|.|   .|    :|...|....:
Mouse     4 DEILHHVGDSGRFQICMIILLNILSLVLSPHDVLENFTAAIPAH---HC----SINLDNSRSEVS 61

  Fly   271 -----------KVSHP----QKEESDDQ---------EFSIDFCNVYQDAQEHAHHYYNYENSD- 310
                       |||.|    ||.|...:         :.:|...|..:...|.....:.|::|.
Mouse    62 TDMNLTTEDLMKVSIPMGPNQKPEQCRRFRYTQWQFLDSNISTFNSTELETEPCLDGWTYDHSVF 126

  Fly   311 ---------QEPRVWEKP--LHRNSNVIPCTEFQHESDYHSVVTQYDLVCSRDILVSVTQFFHLF 364
                     ..|:.|:..  .|....:.||     |....|.|..:||||.........|...|.
Mouse   127 TSTIVTEGLSPPQPWDSDQYYHTKHEISPC-----EEGLKSSVKVWDLVCDFQSFKYYAQATSLA 186

  Fly   365 GVLTGGILANQLLKYFSPRNVMLFGMITQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQ 429
            |.|....|:..:...|..:.:::       :|....|.|.:|  ..|....|..|..:...:..|
Mouse   187 GHLVSCPLSGIISDRFGRKPLLM-------YCSLAYGAVGTY--CAFAPNFSVYCVLRFLLSAFQ 242

  Fly   430 ---------IMADITGGKYRTCVSTLFEQFWSIGVMMLPGVASFWSSWSHLYMAISWPTVILIYL 485
                     ::.:....::...:..|...|.|||..:|.|:|...|.|..|.:|.:.|..|...|
Mouse   243 STILINSLILVLEEASVQWHPTIIVLSGLFNSIGQGVLGGLAYVISDWHLLQLAYALPFFIFFVL 307

  Fly   486 WQWIPDSPRWLIARGRTQDAKKILLECVEVNGTGYNLPHDIDQQL---ELQAQTAMDAPPPSGWW 547
            :.|:|:|.||||..|:|..|.|.|.....:||     ...|.|.|   :|:::...|
Mouse   308 FCWVPESVRWLIITGKTDQAWKELQRIASING-----KKGIAQNLTTEDLRSKLKKD-------- 359

  Fly   548 SMWKGERAVRHIVCVHLAWSLYIVVYYGMLLNIRSFSRDHLYINTFFAG---------FSEMMGT 603
                                   |...|.|..|:.     ::||.....         |:|:. :
Mouse   360 -----------------------VNSTGKLFRIKD-----IFINPLIRKIVLSNSSLLFAELF-S 395

  Fly   604 FFGLFLILKTTRKWLWTGLFNIVAGCIAYCGWLVPKPSV-------IGLDPNVALLMC---SAMV 658
            |.||.|.::...|.::  |..|..|.|.     ||..|:       :...|.:|.|:.   |.:.
Mouse   396 FVGLLLDVQLLGKNMF--LTQIFLGAID-----VPSKSLTYFTIRNVSRRPLIAFLLLTTGSCIT 453

  Fly   659 SKMAISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLLGAPFIGSTVVFGQLIP-------Q 716
            ..:.||..:.:|.|.           |......|:|.|..:      ||....:|.|       .
Mouse   454 ITIFISEEMYVLRTI-----------IFILGKGCFAAFTCI------STTYINELSPVELRSTLN 501

  Fly   717 TAFASLAILGGLCTSLISSPRTHPISRP 744
            ..|.::..|.|:.::|..:.|.:.:..|
Mouse   502 GVFLAVVRLAGVLSALTLATRKYFVYLP 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	MFS_SLC22	329..732	CDD:340875	95/440 (22%)
Slc22a22	XP_036015188.1	MFS_OAT	108..548	CDD:340932	105/502 (21%)