Protein Alignment CG44098 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 598
• Identity: 129/598 - (21%)
• Similarity: 221/598 - (36%)
• Gaps: 116/598 - (19%)

  Fly   206 VDAVGQITGPWGKWQL-RTVLLIFLCKIPSSWFMACII---FTAPAPRHGEFFCKPPHTIGAQNQ 266
            :|.||.:    |::|| :||.|:    .|..|.....:   |:|..|.|.   |..|....:.:|
Mouse     7 LDRVGGL----GRFQLFQTVALV----TPILWVTTQNMLENFSAAVPHHR---CWVPLLDNSTSQ 60

  Fly   267 TQ---------WIKVSHPQKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENSDQEPRVWEKPLHR 322
            ..         .:.||.|...:....:     |..::..|      :....|:.....|.
Mouse    61 ASIPGDLGPDVLLAVSIPPGPDQQPHQ-----CLRFRQPQ------WQLTESNATATNWS----- 109

  Fly   323 NSNVIPCTE---FQHESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRN 384
            ::...||.:   :.|.:...::||.:||||:...|..:.|...|.|:|.|..:.......|..|.
Mouse   110 DAATEPCEDGWVYDHSTFRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRR 174

  Fly   385 VMLFGMITQIFCGNLTGHVASYELHVFFRCL--SAVCCAQMYTAGGQIMADITGGKYRTCVSTLF 447
            |:.:..:.....|.....:.::.|:..||.|  |||....|.||  .::.:.|..:....|.||.
Mouse   175 VLTWSYLLVSVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTA--SLLMEWTSAQGSPLVMTLN 237

  Fly   448 EQFWSIGVMMLPGVASFWSSWSHLYMAISWP-TVILIYLWQWIPDSPRWLIARGRTQDAKKILLE 511
            ...:|.|.::...||....||..|.:|:|.| .:..:|.| |:|:|.||||..|:.....:.|..
Mouse   238 ALGFSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSW-WLPESARWLITVGKLDQGLQELQR 301

  Fly   512 CVEVN---GTGYNLPHDIDQQLELQAQTAMDAPPPSGWWSMWKGERA------------VRHIVC 561
            ...||   ..|..|..::       .::||:..|        ..::|            :||...
Mouse   302 VAAVNRRKAEGDTLTMEV-------LRSAMEEEP--------SRDKAGASLGTLLHTPGLRHRTI 351

  Fly   562 VH-LAWSLYIVVYYGMLLNIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNI 625
            :. |.|..:...:||:.|::::.. .::::.....|..:.......|.||.:..|: |....|.:
Mouse   352 ISMLCWFAFGFTFYGLALDLQALG-SNIFLLQALIGIVDFPVKTGSLLLISRLGRR-LCQVSFLV 414

  Fly   626 VAGCIAYCGWLVPKP--------SVIGLDPNVALLMCSAMVSKMAISTTLSILTT--CTVELVSD 680
            :.|.......|||..        :|:||........|..:.|.....|.:.:...  |.|.
Mouse   415 LPGLCILSNILVPHGMGVLRSALAVLGLGCLGGAFTCITIFSSELFPTVIRMTAVGLCQVA---- 475

  Fly   681 DKKKITSFSTICWARFWLLGAPFIGSTVVFGQLIPQTAFASLAILGGLCTSLISSPRTHPISRPS 745
                         ||...:..|.:....|:|..:|...:..:.:|.||...|:  |.|..:..|.
Mouse   476 -------------ARGGAMLGPLVRLLGVYGSWMPLLVYGVVPVLSGLAALLL--PETKNLPLPD 525

  Fly   746 SPAAQGTQNITSQ 758
            :     .|:|..|
Mouse   526 T-----IQDIQKQ 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	119/560 (21%)
		MFS	353..733	CDD:119392	88/408 (22%)
Slc22a12	NP_033229.3	2A0119	11..526	CDD:273328	124/580 (21%)
		MFS	147..516	CDD:119392	88/407 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843308
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930