Protein Alignment CG44098 and Slc22a1

DIOPT Version :9

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_033228.2
• Gene: Slc22a1 / 20517
• MGIID: 108111
• Length: 556
• Species: Mus musculus
• Alignment Length: 615
• Identity: 136/615 - (22%)
• Similarity: 249/615 - (40%)
• Gaps: 94/615 - (15%)

  Fly   206 VDAVGQITGPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQTQW- 269
            ||.|.:..|.:|.:|.:..||:.|.....:.....|:|....|.|   .|:.|.......:..|
Mouse     4 VDDVLEHVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPDH---HCRSPGVAELSQRCGWS 65

  Fly   270 ----IKVSHPQKEESDDQEFSIDFCNVYQ-DAQEHAHHYYNYENSD-QEPRVWEKPLHRNSNVIP 328
                :..:.|....:.:..| :..|..|: |        :|....| .:|.   ..|..|.:.:|
Mouse    66 PAEELNYTVPGLGSAGEASF-LSQCMKYEVD--------WNQSTLDCVDPL---SSLAANRSHLP 118

  Fly   329 CTEFQH----ESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFG 389
            .:..:|    ::...|:||:::|||.....|.:.|.....|...|.::...:...|..:..:|..
Mouse   119 LSPCEHGWVYDTPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVT 183

  Fly   390 MITQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVSTLFEQFWSIG 454
            .:.....|.||.....|...:.||.|..:.....:.:|..::.:..|..||...:.|::..:::|
Mouse   184 TLVTSLSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQVAFTVG 248

  Fly   455 VMMLPGVASFWSSWSHLYMAISWPT-VILIYLWQWIPDSPRWLIARGRTQDAKKILLECVEVNGT 518
            ::.|.|||.....|..|.:|:|.|| :.|:|.| ::|:|||||:::.||..|.:|:.:..:.|
Mouse   249 LVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYW-FVPESPRWLLSQKRTTQAVRIMEQIAQKN-- 310

  Fly   519 GYNLPHDIDQQLELQAQTAMDAPPPSGWWSMWKGERAVRHIVCVHLAWSLYIVVYYGMLLNIRSF 583
             ..:| ..|.::....:.|.:...|| :..:::.....:|.:.:...|....|:|.|:::::.:
Mouse   311 -RKVP-PADLKMMCLEEDASERRSPS-FADLFRTPSLRKHTLILMYLWFSCAVLYQGLIMHVGA- 371

  Fly   584 SRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIAYC----------GWLVP 638
            :..:||::.|::...|....|..|..|.:..|.:. ....|:|||  |.|          .||
Mouse   372 TGANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYP-IAASNLVAG--AACLLMIFIPHELHWL-- 431

  Fly   639 KPSVIGLDPNVALLMCSAMVSKMAISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLLG--A 701
                     ||.|    |.:.:|..:..|.::.....||.....:.:...  :|.|...|.|  .
Mouse   432 ---------NVTL----ACLGRMGATIVLQMVCLVNAELYPTFIRNLGMM--VCSALCDLGGIFT 481

  Fly   702 PFIGSTVVF-----GQLIPQTAFASLAILGGLCTSLISSPRTHPISRPSSPAAQGTQNITSQFTI 761
            ||    :||     .|.:|...|..|.:..|..|.|:  |.|..::.|.:
Mouse   482 PF----MVFRLMEVWQALPLILFGVLGLSAGAVTLLL--PETKGVALPET--------------- 525

  Fly   762 IDGMDNKGYSPTSKTIHSNSTILKLNTPQS 791
            |:..:|.|...:.  ...|:..|::.|.:|
Mouse   526 IEEAENLGRRKSK--AKENTIYLQVQTGKS 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	121/544 (22%)
		MFS	353..733	CDD:119392	91/397 (23%)
Slc22a1	NP_033228.2	2A0119	12..525	CDD:273328	126/560 (23%)
		MFS	125..515	CDD:119392	98/422 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843610
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850