Protein Alignment CG44098 and Slc22a25

DIOPT Version :10

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_620263.1
• Gene: Slc22a25 / 192273
• RGDID: 621104
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 616
• Identity: 130/616 - (21%)
• Similarity: 239/616 - (38%)
• Gaps: 107/616 - (17%)

  Fly   207 DAVGQITGPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPP----HTI-----G 262
            |.:.|: |..|::|:..:..|.:..|..|.......|||..|.|.   |..|    .|:     |
  Rat     5 DLLNQV-GSLGRFQILQMTFILIFNIIISPHSLLENFTAVIPNHR---CWVPILDNDTVSGNDNG 65

  Fly   263 AQNQTQWIKVSHPQKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENSDQEPRVWEKPLHRNSNVI 327
            ..:|...::||.|.     |.:...:.|..:...|....|.....:|..||           :..
  Rat    66 NLSQDDLLRVSIPL-----DSDLRPEKCRRFVQPQWDLLHLNGTFSSVTEP-----------DTE 114

  Fly   328 PCTE---FQHESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFG 389
            ||.:   :...:...:::|::||||....|.|:.:|..|.|:|.|.||...|...|..|.:::..
  Rat   115 PCVDGWVYDQSTFLSTIITEWDLVCESQSLDSIAKFLFLTGILVGNILYGPLTDRFGRRLILICA 179

  Fly   390 MITQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVSTLFEQFWSIG 454
            .:.............::.::...|.|:.:..:.:.|....::.:.|..|::...:.|.....:||
  Rat   180 SLQMAVTETCAAFAPTFLIYCSLRFLAGISFSTVLTNSALLIIEWTRPKFQALATGLLLCAGAIG 244

  Fly   455 VMMLPGVASFWSSWSHLYMAISWPTVILIYLWQWIPDSPRWLIARGRTQDAKKILLECVEVNGTG 519
            ..:|.|:|....:|.||::|:|.|...|:...:|:.:|.||||...:.|...|.|::...:||
  Rat   245 QTVLAGLAFTVRNWHHLHLAMSVPIFFLLVPTRWLSESARWLIMTNKLQKGLKELIKVAHING-- 307

  Fly   520 YNLPHDID----------QQLELQA-QTAMDAPPPSGWWSMWKGERAVRHIVCVHLAWSLYIVVY 573
              :.:..|          .:.||:| ||      .|..|.:::.....:.|..:.|...:..:..
  Rat   308 --MKNSTDVLTIEVVRTIMKEELEASQT------KSSLWDLFRTPNLRKRICLLSLVRFVVWLSV 364

  Fly   574 YGMLLNIRSFSRDHLYINTF----FAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIAYCG 634
            .|:|:|.:     ||.||.|    ..|...:.....|:||:....|:  .:.||.|
  Rat   365 IGLLINFQ-----HLRINVFLLQCLLGIITIPANLVGIFLVNHLGRR--ISQLFII--------- 413

  Fly   635 WLVPKPSVIGLDPNVALLMCSAM-VSKMAISTTLSILTTCTVE--LVSDDKKKITSFSTICWARF 696
                  |:.|:.....:.:...| :.:|.::|...:.:..:|.  ||..::...|..........
  Rat   414 ------SLFGISILAIIFVPQEMQILRMVLATFGGVFSFVSVSSALVHANELLPTIIRATALGVI 472

  Fly   697 WLLG------APFIGSTVVFGQLIPQTAFASLAILGGLCTSLISSPRTHPISRPSSPAAQGTQNI 755
            .:.|      :|.......:...:|...:..|:.||||...|:...:..|:  |.|
  Rat   473 GIAGSTGAALSPLFMILRTYSDSLPWIIYGVLSFLGGLVVLLLPETKNQPL--PDS--------- 526

  Fly   756 TSQFTIIDGMDNKGYSPTSKTIHSNSTILKL 786
                  |..::|:|.:  |:....|.|::|:
  Rat   527 ------IQDVENEGRA--SRQGKQNDTLIKV 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	MFS_SLC22	329..732	CDD:340875	90/429 (21%)
Slc22a25	NP_620263.1	MFS_OAT	109..506	CDD:340932	89/439 (20%)