DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG44098 and Y82E9BR.16

DIOPT Version :9

Sequence 1:	NP_001262264.1	Gene:	CG44098 / 40590	FlyBaseID:	FBgn0264907	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_001022960.1	Gene:	Y82E9BR.16 / 175300	WormBaseID:	WBGene00022348	Length:	575	Species:	Caenorhabditis elegans

Alignment Length:	593	Identity:	127/593 - (21%)
Similarity:	229/593 - (38%)	Gaps:	116/593 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 GPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQTQW--IKVSHPQ 276
            |..||:|          ||  .:|:.|:                |..:.:.:...|  ..|..|.
Worm    12 GEMGKYQ----------KI--QFFLVCL----------------PTIVVSMHALSWTFASVDTPY 48

  Fly   277 KEESDDQEFSIDFCNVYQDAQEHAHHYYNYEN-----SDQEPRV----WEKP---LHRNSNVIP- 328
            :            |.:..|..|...:|....|     :|.:..|    :.||   .|.:...:|
Worm    49 R------------CRLPSDLPEKEPYYTTLLNFTKCTNDADANVPISEYGKPGVTCHYDRCTLPD 101

  Fly   329 ---CTE--FQHESDYHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLF 388
               |.|  |.|....::.|.::::.|.|..:.:..|..:..|.:.|......|......:.|...
Worm   102 NETCHEHIFDHSKVEYTAVQRWEITCDRSWIKATIQAAYYVGQMAGSTTFGMLGDRIGRKKVFFL 166

  Fly   389 GMITQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVSTLFEQFWSI 453
            .::.||.|..|......:.|:...|..:......::.....|..::.|.|||...|.:...|:::
Worm   167 AIVIQITCAYLIAIAPYWWLYALARAGTGFSHPGIFVIAVVIGMELVGPKYRKLASVITGLFFAL 231

  Fly   454 GVMMLPGVASFWSSWSHLYMAISWPTVILI----------------------------YLWQW-I 489
            |.:.|...|.:::::..|::.|:.|.::.:                            :..:| :
Worm   232 GQIFLGIEAIYFTNYQILHVVIASPALLFLSYCQKSAKNRKKIDFANFLADFLLKNRFFFSRWLV 296

  Fly   490 PDSPRWLIARGRTQDAKKILLECVEVNGTGYNLPHDIDQQLELQAQTAMDAP-PPSGWWS---MW 550
            |:|.|||:::.|.::|.::|.:...||||  .||.:..:||:........|| .|:...:   ::
Worm   297 PESARWLVSQKRYKEADEVLQKAASVNGT--VLPENWWEQLDDSTTGGGGAPGAPTKKLTGADLF 359

  Fly   551 KGERAVRHIVCVHLAWSLYIVVYYGMLLNIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTR 615
            :.....:..:.|...|.:..:|||||.:.......| :|:|..||.|.|:...|....||.:..|
Worm   360 RTPELRKRTLVVFFLWPVISMVYYGMAMKANVLGGD-IYVNFIFAAFVEIPALFIVYLLIDRIGR 423

  Fly   616 KWLWT-GLFNIVAGCIAYCGWLVPKPSVIGLDPNVALLMCSAMV--SKMAISTTLSILTTCTVEL 677
            :.:.. |||  :||......||        :..||.|.|....:  :|.:|:...:.:.|.:.||
Worm   424 RLILAGGLF--IAGACLLVNWL--------MGDNVQLWMAITQMAFTKGSITGVYAAIYTYSPEL 478

  Fly   678 V-SDDKKKITSF-STICWARFWLLGAPFIGSTVV--FGQLIPQTAFASLAILGGLCTSLISSPRT 738
            . :..:.....| |||  ||...:.|.:|...:.  ||::.....|..:|:|..:.| |:..|.|
Worm   479 FPTVIRNTAMGFCSTI--ARVGAIAASYISMWIAEQFGKVFMIIPFGCMAVLAAVMT-LLFLPET 540

  Fly   739 HPISRPSS 746
            .....|.|
Worm   541 MGKPLPES 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	121/575 (21%)
CG44098	NP_001262264.1	MFS	353..733	CDD:119392	92/419 (22%)
Y82E9BR.16	NP_001022960.1	MFS_SLC22	107..537	CDD:340875	99/445 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920