Protein Alignment CG44098 and K05F1.6

DIOPT Version :10

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_001342018.1
• Gene: K05F1.6 / 173977
• WormBaseID: WBGene00019408
• Length: 858
• Species: Caenorhabditis elegans
• Alignment Length: 868
• Identity: 184/868 - (21%)
• Similarity: 329/868 - (37%)
• Gaps: 156/868 - (17%)

  Fly    27 LVSGLHSSDSSSGIGSASSEKLATRSDETHAQRRSSGEGDADEDADDDDDDED------EDEDDG 85
            |::.::.||..:..|:.::          |....|..|...:.|....:|.:.      .|||:|
 Worm    11 LITPINLSDLDTSPGAHAN----------HTYEGSDPEEPEEVDIHIPNDTQSLCVSTGRDEDEG 65

  Fly    86 DETTAES---PLLPLKEDEP---SPPQVHSSSHISASRS----PHFGTSAGDL---------EPK 131
            ...|..:   ..:||...||   :.|.:..:.|.|.:.|    ||....|.::         ||:
 Worm    66 RSITPNNMAYEFIPLIYSEPALFNMPDISYNLHKSFAASDTLLPHMRVVADEMRNTSASVTAEPE 130

  Fly   132 HLPLAPNSPSNEQAKCEGPEGEANNNNSTSSNHNHNPN-HIRTHRRQHE--YQLYPN-DTFAQLE 192
              |...::||..............::.|......|.|: ..|..|.||:  .|:|.: :...:.|
 Worm   131 --PSVSHAPSVLTVTAPEDRNMYQSDISMYGRQGHKPSFSTREIREQHQKVQQIYRDVNKKERKE 193

  Fly   193 GKAPKPNTKMQTKVDAVG--QITGPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFC 255
            ||...|       :|..|  .|.|....||:...:||.|.:||.:.|...:::....|   ||.|
 Worm   194 GKPTDP-------IDFEGILNIIGGCRWWQIWIYVLIALQQIPHAMFNLNVVYMMYDP---EFQC 248

  Fly   256 KPP-------HTIGAQNQTQWIKVSHPQKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENSDQEP 313
            ..|       .||.:.....|        ...|.:..|..|.|...|........|.||.|::..
 Worm   249 MVPGFNDTNDTTISSHGPYLW--------GVDDIKNISFVFPNANSDGAYQRDSCYFYERSEERY 305

  Fly   314 RVWEK-PLHRN-----SNVIP---CTEFQHESD--YHSVVTQYDLVCSRDILVSVTQFF----HL 363
            |...: ||...     .:|.|   |..:..|.|  ..::||.::|||...........|    :|
 Worm   306 RQLRRMPLETAMSEAWKDVAPKKKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYL 370

  Fly   364 FGVLTGGILANQLLKYFSPRNVMLFGMITQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGG 428
            .|.:.|||.::::.:  .| .::.||:::.:. |........|.:.:..|.|||:|......|..
 Worm   371 LGCVLGGIASDKIGR--KP-TIIGFGILSSML-GVFLPFNDYYPMFLLIRLLSAICNEAADLAAY 431

  Fly   429 QIMADITGGKYRTCVSTLFEQFWSIGVMMLPGVASFWSSWSHLYM---AISWPTVILIYLWQWIP 490
            .:..:|||.|||..|.::.:..|::|..:|..:|....||..:.:   .:.:.::|.|..   ||
 Worm   432 TLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAGLHFMSIIFICS---IP 493

  Fly   491 DSPRWLIARGRTQDAKKILLE-CVE---------VNGTGYNLPHDIDQQLELQAQTAMDAPPPSG 545
            :|||||:.:.|..:|::::.: |.|         .:..| |||.|::.....:.:.........|
 Worm   494 ESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCTTSKCG-NLPSDLELVSHRERKLNKKNGGKIG 557

  Fly   546 WWSMWKGERAVRHIVCVHLAWSLYIVVYYGMLLNI-------RSFSRDHLYINTFFAGFSEMMGT 603
            :..::..:......:.|.:.:....:||||:::.:       |:....:.::|...||..| :.|
 Worm   558 FLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIE-IPT 621

  Fly   604 FFGLFLILKTTRK------WLWTGLFNIVAGCIAYCGWLVPKPSVIGLDPNVALLMCSAMVSKMA 662
            .|....:::..||      .:.:|||.|||......|             :..|.:......|:|
 Worm   622 LFACVWMMQLGRKKALMLTLITSGLFIIVAMLSMVSG-------------HYMLALAFMYFGKIA 673

  Fly   663 ISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLLGAPFIG--STVVFGQLIPQTAFASLAIL 725
            :....:||...|.||.....:......|...|||....:.:|.  |.:.. .::|...||..::.
 Worm   674 VQGAFNILYIFTSELYPTVVRNTAVGVTSMVARFGSGLSSYIALLSNISL-PIVPMIIFAVFSLF 737

  Fly   726 GGLCTSLISSPRTHPISRPSS---------PAAQ-----------GTQNITSQFTIIDGMDNKGY 770
            .|:...::  |.|.....|.:         |..|           |.|.:|...::.:.......
 Worm   738 AGMLVFVL--PETSEKPLPETLDDAINFLEPTKQVNCMMGRFGVFGHQKMTKSISLTENPSTNDI 800

  Fly   771 SPTSKTIHSNSTILKLNTPQSNL 793
            :........:|.|.:..|.::::
 Worm   801 ADLKPLSRRSSAITRRMTERASV 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	MFS_SLC22	329..732	CDD:340875	96/436 (22%)
K05F1.6	NP_001342018.1	MFS_SLC22	333..746	CDD:340875	95/437 (22%)