DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG44098 and Ust5r

DIOPT Version :9

Sequence 1:	NP_001262264.1	Gene:	CG44098 / 40590	FlyBaseID:	FBgn0264907	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_599207.2	Gene:	Ust5r / 171398	RGDID:	620985	Length:	552	Species:	Rattus norvegicus

Alignment Length:	572	Identity:	120/572 - (20%)
Similarity:	228/572 - (39%)	Gaps:	85/572 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 QTKVDAVGQITGPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPP--------- 258
            |..::.||.:    |::|:..:..:||..:..........|||..|.|.   |..|
  Rat     4 QELLNQVGSL----GRFQILQMAFVFLINVSVVPHSTIENFTAAIPSHR---CWVPILDNVTVSD 61

  Fly   259 -HTIGAQNQTQWIKVSHPQKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENSDQEPRVWEKPLHR 322
             |: ...||.:.:|:|.|.     |....:|.|..:...|.|.     .:.:|....|.|
  Rat    62 NHS-RILNQDKLLKISIPL-----DSHLRLDKCRRFAQPQWHL-----LDLNDTFSSVTE----- 110

  Fly   323 NSNVIPCTE--FQHESDYHS-VVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRN 384
             ::..||.:  ....|::|| .||::||||...:|.|||:|..:.|...|||:...|...|..:.
  Rat   111 -ADTEPCVDGWVYDRSNFHSTTVTEWDLVCESQVLNSVTKFSFMIGAFIGGIVNGPLSDRFGRKF 174

  Fly   385 VMLFGMITQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVSTLFEQ 449
            |:...::.........|..:::.::...|.|:.:....:......:|.:.|..|:...:|.:...
  Rat   175 VLKCALLQMAITETCVGFASNFFIYCSLRFLAGMTFEPILVNSNLLMFEWTSHKFLAMMSVIAPC 239

  Fly   450 FWSIGVMMLPGVASFWSSWSHLYMAISWPTVILIYLWQWIPDSPRWLIARGRTQDAKKILLECVE 514
            ..|.|.|:|.|:|..:.:|.||.:|:|.|....:.|.:|:.:|.||||...:.|...|.|.:...
  Rat   240 AGSFGSMILAGLAFQFQNWHHLQLAMSVPIFFFLILTRWLSESARWLIVTNKPQKGLKELRKVAH 304

  Fly   515 VNG---TGYNLPHDI---DQQLELQAQTAMDAPPPSGWWSMWKGERAVRH-------IVCVHLAW 566
            :||   :|.||..::   ..:.||:|..|..:|            |.:.|       |..:....
  Rat   305 MNGMKNSGDNLTMEVVRTSMKRELEAAKARPSP------------RDLFHTPILRKRICAMSFMR 357

  Fly   567 SLYIVVYYGMLLNIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIA 631
            .|:::..:||.|:::..| .::.:..|....|.::.:..|.::..:..|:.....:..:...||.
  Rat   358 ILFMLSIFGMSLHLQHLS-SNIMLLQFVVSASSLLFSVIGPYVFNRMGRRITQMVVMTLRGICIL 421

  Fly   632 YCGWLVPKPSVIGLDPNVALLMCSAMVSKMAIST----TLSILTTCTVELVSDDKKKITSFSTIC 692
            ...::..:..::    .:.::..:...|.::...    |..:|.|..         :.|:...|.
  Rat   422 TAVFVPQEMQIL----RITVVTLAGAFSALSFGVNRLHTNELLPTTL---------RATAIGVIG 473

  Fly   693 W---ARFWLLGAPFIGSTVVFGQLIPQTAFASLAILGGLCTSLISSPRTHPI 741
            .   :.|:|  ||.......:...:|...:...:||.|....|:...:..|:
  Rat   474 MFGNSGFFL--APLFMILASYSPNLPWIFYGGFSILNGFTVFLLPETKNQPL 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	115/548 (21%)
CG44098	NP_001262264.1	MFS	353..733	CDD:119392	79/399 (20%)
Ust5r	NP_599207.2	MFS_OAT	109..516	CDD:340932	92/440 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347088
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840