Protein Alignment CG44098 and SLC22A7

DIOPT Version :9

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: XP_011512558.1
• Gene: SLC22A7 / 10864
• HGNCID: 10971
• Length: 610
• Species: Homo sapiens
• Alignment Length: 655
• Identity: 127/655 - (19%)
• Similarity: 217/655 - (33%)
• Gaps: 187/655 - (28%)

  Fly   214 GPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPPHTIGA----QNQTQWIKVSH 274
            |.:|.:|||.|.|:.|.::.........||.|..|.|.   |..|   ||    .:|..|::...
Human    11 GGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHR---CALP---GAPANFSHQDVWLEAHL 69

  Fly   275 PQKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENS-----DQEPRVWEKPLHRNSNVIPCT---E 331
            |::.:.     ::..|..:...|...:.....|..     :.||.           .:||:   |
Human    70 PREPDG-----TLSSCLRFAYPQALPNTTLGEERQSRGELEDEPA-----------TVPCSQGWE 118

  Fly   332 FQHESDYHSVVT----------------------------------------------------- 343
            :.| |::.|.:.
Human   119 YDH-SEFSSTIATESQVGIYIIHLEVECRWRQSPWEAAGRGLPWEEAEAAGLGRDKVSYSPSWRE 182

  Fly   344 ---------QYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFGMITQIFCGNL 399
                     ::||||.:..|......|...|||.|.:....|...|..|.::|...::.:..|..
Human   183 SLGGLLSGMEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLA 247

  Fly   400 TGHVASYELHVFFRCLSAVCCAQ---MYTAGGQIMADITGGKYRTCVSTLFEQFWSIGVMMLPGV 461
            :....||.:....|.|:....|.   :....|:...:....::||....|...||:.|||:|..|
Human   248 SAASVSYVMFAITRTLTGSALAGFTIIVMPLGEAELEWLDVEHRTVAGVLSSTFWTGGVMLLALV 312

  Fly   462 ASFWSSWSHLYMAISWPTVI-LIYLWQWIPDSPRWLIARGRTQDAKKILLECVEVNGTGYNLPHD 525
            ......|..|.:|::.|... ::.|| |:|:|.|||:.:|..::|.:.||.|..:||...
Human   313 GYLIRDWRWLLLAVTLPCAPGILSLW-WVPESARWLLTQGHVKEAHRYLLHCARLNGRPV----- 371

  Fly   526 IDQQLELQAQTAMDAPPPSGWWSMWKGERAV--------------RHI-VCVHLAWSLYIVVYYG 575
            .:.....:|.:.:.|           |||.|              ||| :|..:.|......|||
Human   372 CEDSFSQEAVSKVAA-----------GERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYG 425

  Fly   576 MLLNIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIAYCGWLVPKP 640
            :.|::..... ::|......|..|:.........:....|:....|  .::...:|:
Human   426 LSLDVSGLGL-NVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAG--TLLGTALAF-------- 479

  Fly   641 SVIGLDPNVALLMCSAMVSKMAISTTLSILTTCTVELVSDDKKKITS--FSTICWARFWLLGAPF 703
                   ...||:.|.|.|   .||.|:::.....|.........||  :.|:       |....
Human   480 -------GTRLLVSSDMKS---WSTVLAVMGKAFSEAAFTTAYLFTSELYPTV-------LRQTG 527

  Fly   704 IGSTVVFGQL-----------------IPQTAFASLAILGGLCTSLISSPR-------THPISRP 744
            :|.|.:.|:|                 :|:..:..:|:|......|:...|       ...:.|.
Human   528 MGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERK 592

  Fly   745 SSPAA 749
            |:|.:
Human   593 SAPTS 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	122/627 (19%)
		MFS	353..733	CDD:119392	87/417 (21%)
SLC22A7	XP_011512558.1	2A0119	11..585	CDD:273328	124/641 (19%)
		MFS	206..563	CDD:119392	84/401 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153501
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840