DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG44098 and slc22a6

DIOPT Version :9

Sequence 1:	NP_001262264.1	Gene:	CG44098 / 40590	FlyBaseID:	FBgn0264907	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	XP_002937540.1	Gene:	slc22a6 / 100487511	XenbaseID:	XB-GENE-5842250	Length:	552	Species:	Xenopus tropicalis

Alignment Length:	555	Identity:	131/555 - (23%)
Similarity:	213/555 - (38%)	Gaps:	69/555 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 GPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQT-QWIKVSHPQK 277
            |..|::|:..|:|:.|.....:.......|||..|||.   |:...:....|.| .|::...|.|
Frog    11 GGMGRYQVIHVVLLSLPVFMLASHNLMQNFTAAIPRHR---CQINGSFEETNFTGPWLRALVPMK 72

  Fly   278 EESDDQEFSIDFCNVYQDAQEHA---HHYYNYENSDQEPRV--WEKPLHRNSNVIPCTEFQHESD 337
            ...   |||  .|..|...|.|.   :...|.:..:.|..|  |              .:.|...
Frog    73 PTG---EFS--KCLRYTTPQYHLLMDNFTQNVDELETETCVDGW--------------VYDHSEF 118

  Fly   338 YHSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFGMITQIFCGNLTGH 402
            ..:::||:||||:...:..|.|..::.|||.|.::...|...|..|.:.::..:.....|.....
Frog   119 ASTIITQWDLVCNHRRMRQVAQSIYMAGVLVGSVVFGGLSDKFGRRPLNIWSNLQMSVTGICAAF 183

  Fly   403 VASYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVSTLFEQFWSIGVMMLPGVASFWSS 467
            ..:|..:..||.|:....:.:......::.:......|...||.....:::|.::|.|:|.....
Frog   184 SPNYIWYCIFRFLTGTALSGIVLNSYSLIVEWIPTGNRAFTSTATGYCYTMGQLVLVGLAFMIRD 248

  Fly   468 WSHLYMAISWPTVI-LIYLWQWIPDSPRWLIARGRTQDAKKILLECVEVNG---TGYNLPHDI-- 526
            |..|.:|.|.|... .:|.| |||:|.|||:..|:.:.|.|.|.:..::||   .|..|..::
Frog   249 WHWLQLAASLPFFFYFLYSW-WIPESGRWLVLSGKPEVACKALKKVAKINGKKEAGEKLTVEVLK 312

  Fly   527 -DQQLELQAQ-----TAMD---APPPSGWWSMWKGERAVRHI-VCVHLAWSLYIVVYYGMLLNIR 581
             ..|.|:.|.     :.:|   .|             .||.| .|:...|......|||:.|:::
Frog   313 SSMQREISASKHSTYSVLDLVRTP-------------VVRRISFCISCTWFSTSFAYYGLALDLQ 364

  Fly   582 SFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIAYCGWLVPKPSVIGLD 646
            ||... :||.....|..::...||..|::....|:.| ..|..|:||........||:..
Frog   365 SFGVS-IYIIQIIFGTVDIPAKFFSYFVMTYIGRRVL-QALTLILAGIAILVNICVPQDY----- 422

  Fly   647 PNVALLMCSAMVSKMAISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLLGAPFIGSTVVFG 711
            ..|...|  |:..|..::.:.:.|...|.||.....::.........||...:.||....|....
Frog   423 QTVRTSM--AVFGKGCLAASFNCLFLYTGELYPTVIRQSGMGLGTMMARLGGIIAPLAQMTGDIY 485

  Fly   712 QLIPQTAFASLAILGGLCTSLISSPRTHPISRPSS 746
            ..:|...|..|.||.|:....:  |.|..:..|.:
Frog   486 HSLPLIIFGCLPILSGIAGCFL--PETLGVPLPET 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	128/537 (24%)
CG44098	NP_001262264.1	MFS	353..733	CDD:119392	92/395 (23%)
slc22a6	XP_002937540.1	MFS_SLC22A6_OAT1_like	102..508	CDD:341004	102/444 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010