DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44098 and slc22a31

DIOPT Version :9

Sequence 1:	NP_001262264.1	Gene:	CG44098 / 40590	FlyBaseID:	FBgn0264907	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	XP_012817743.1	Gene:	slc22a31 / 100485676	XenbaseID:	XB-GENE-6048942	Length:	558	Species:	Xenopus tropicalis

Alignment Length:	515	Identity:	109/515 - (21%)
Similarity:	194/515 - (37%)	Gaps:	82/515 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   316 WEKPLHRNSNVIPCTEFQHESDYHS-VVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKY 379
            ||...:::.:......||.:...:| :|||::|:|.|...|.:.:..:|.|.|.|.|:...:...
Frog    64 WENSSNQSQHCPGGWHFQAQGWLNSNIVTQWELLCDRQWKVPLEKISYLVGWLLGYIIFGCICDR 128

  Fly   380 FSPRNVMLFGMITQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVS 444
            ...|...:..::..:..|......:||...:..|.......|.|:.:......::.....|..|:
Frog   129 LGRRAAFIGALVMALPLGVAVTFTSSYFSFLPLRAGFGAALAGMFLSFYISRVELCSPSQRLMVT 193

  Fly   445 TLFEQFWSIGVMMLPGVASFWSSWSHLYMAISWPTVILIYLW---QWIPDSPRWLIARGRTQDAK 506
            .:...||..|.::|||:|...|.|..|..:|:...::|...|   ...|:|||||:|..:.:..|
Frog   194 MIGGFFWVAGELLLPGMAVLCSDWRVLQGSITGTLMLLGVYWCGHTLYPESPRWLLATQQVEQCK 258

  Fly   507 KILLECVEVNGTGYNLPHDIDQQLELQAQTAMDAPPPSGWWSMWKG-ERAVRHIVC----VHLAW 566
            ..|......|  |.|:..|...|..:  .|.:|        |:.:| .|...:.:|    ..|.|
Frog   259 SELHMFARAN--GINIGEDASGQDHV--FTEID--------SLCEGFPRPQYYSICSIFGTRLIW 311

  Fly   567 SLYIVVYYGMLL----------NIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTG 621
            ...:::.:...:          |::.|..   ||..|....||::........:....|:.:..
Frog   312 RNALILGFTAFIGCGIRPCFARNLQVFGP---YIPYFLQAGSEIVACILICICVSHCGRRSVLL- 372

  Fly   622 LFNIVAGCIAYCGWLVPKPSVIGLDPNVALL------MCSAMVSKMAISTTLSILTTCTVELVSD 680
            ||.|:.|   :|..|:...:.:.|....:::      :||..|..:::.....:|.|..
Frog   373 LFTILTG---FCSLLLLALTQLDLFIEASIVISVVGSLCSHAVVMLSVFYACEVLPTVI------ 428

  Fly   681 DKKKITSFSTICWARFWLLG---APFIGSTVVFGQLIPQTAFASLAILGGLCTSLISSPRTHPIS 742
               :.:....|....  :||   .|||......|..:.....:|..||..|  ||:..|.|...|
Frog   429 ---RGSGLGLIMGIN--MLGRASLPFIELQHKSGYFLYHVVLSSFCILSVL--SLLLLPETKRKS 486

  Fly   743 RPSSPAAQGTQNI--------TSQFT---IIDGMDNKGYSP---------TSKTIHSNST 782
            .|.:  .:..:|:        .:|.|   :..|.....|:|         |.|.|.|::|
Frog   487 LPET--LRHGENLRRPPLLLHPTQDTLPLLKHGKKRADYNPDSYARLASSTKKMIRSDTT 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	92/441 (21%)
CG44098	NP_001262264.1	MFS	353..733	CDD:119392	82/406 (20%)
slc22a31	XP_012817743.1	MFS	110..470	CDD:119392	77/389 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910