DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44098 and slc22a13a

DIOPT Version :9

Sequence 1:	NP_001262264.1	Gene:	CG44098 / 40590	FlyBaseID:	FBgn0264907	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	XP_021322911.1	Gene:	slc22a13a / 100007819	ZFINID:	ZDB-GENE-070912-473	Length:	537	Species:	Danio rerio

Alignment Length:	590	Identity:	133/590 - (22%)
Similarity:	232/590 - (39%)	Gaps:	107/590 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 GQITGPWGKWQLRTVLLIFLCKIPS---SWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQTQWIK 271
            |:|....|.:.|...||:|....|:   .:.::.::|......|   .|          .|.||.
Zfish     5 GEILEAIGDFGLFQKLLLFALCFPNLILPFQLSSLVFNHADTNH---HC----------NTDWIL 56

  Fly   272 VSHPQ--KEE---------SDDQEFSIDFCNVYQDAQEHAHHYYNYENSDQEPRVWEKPLHRNSN 325
            .:.|.  |||         ||.   |.:.|.:|                        ||:..|.:
Zfish    57 KADPNLTKEEQLNLTLPRLSDG---SFNPCQMY------------------------KPVDWNLS 94

  Fly   326 VI---------PCTE--FQHESDYH-SVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLK 378
            .|         .||:  ..:::.|. ::||.:||||....:....|.....|||.|.||.....:
Zfish    95 AIQEYGLNQTTTCTDGWVHNDTIYEATIVTDFDLVCENVNIFRGAQTVFFAGVLVGAILFGPFSE 159

  Fly   379 YFSPRNVMLFGMITQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQIMAD----ITGGKY 439
            .|..:......|:..:....:||...::.:::..:.::.|.... :.....|:|.    :....|
Zfish   160 SFGRKRATQIPMVLMLIFTVVTGLSPNFYVYLVSQFINGVGLGG-FRINSIILASEWIGVAQRSY 223

  Fly   440 RTCVSTLFEQFWSIGVMMLPGVASFWSSWSHLYMAISWPT-VILIYLWQWIPDSPRWLIARGRTQ 503
            ..|:|.:..   ::|.:|...|..|...|......::.|. :::||:| ::|:|.|||:.||||:
Zfish   224 AACLSQVLA---ALGQVMFLAVVYFVRDWRLDQFIMAGPIGIVVIYIW-FLPESARWLLDRGRTK 284

  Fly   504 DAKKILLECVEVNGTGYNLPHDIDQQLELQAQTAMDAPPPSGWWSMWKGERAVR-HIVCVHLAWS 567
            ||||::.:...||...  :|..:.:::      ..:.|...|...:..|.|.:| :.:.:..||.
Zfish   285 DAKKLIQKAAAVNKRA--VPESLVEEV------LKEKPVEKGGIKILFGSRVLRKYFLAITFAWC 341

  Fly   568 LYIVVYYGMLLNIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRK-WLWTGLFNIVAGCIA 631
            ...:.||.:.||:..|..| :::.....|.||:...|..::.:....|| .|...|  ::.||:.
Zfish   342 ALNLAYYSLSLNVGKFGLD-IFLTQLIFGLSEIPVHFLCMWSLEVVGRKPSLIVSL--VLGGCLC 403

  Fly   632 YCGWLVPKPSVIGLDPNVALLMCSAMVSKMAISTTLSILTTCTV---ELVSDDKKKITSFSTICW 693
            .....||:.|.|.:   ..|..|...:...|.|       .|.|   ||.....::..:......
Zfish   404 LLTVAVPQNSSIAI---AVLATCGRFLMNAAGS-------VCNVYFQELFPTSIRQTATGLGSTA 458

  Fly   694 ARFWLLGAPFIGSTVVFGQLIPQTAFASLAILGGLCTSLISSPRTHPISRP-SSPAAQGTQ--NI 755
            ||...:.:|.:....:|...||....:|||:..|:...|:  |.|.....| |:..|:|.:  .:
Zfish   459 ARAGSMLSPVVNMLEIFHFSIPMVVISSLALASGVTAFLL--PETRRTELPASTEEAEGKRKPKL 521

  Fly   756 TSQFT 760
            ||..|
Zfish   522 TSPAT 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	121/551 (22%)
CG44098	NP_001262264.1	MFS	353..733	CDD:119392	87/389 (22%)
slc22a13a	XP_021322911.1	Sugar_tr	12..507	CDD:331684	124/562 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588672
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.850