Protein Alignment CG44098 and slc22a5

DIOPT Version :10

• Sequence 1: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: XP_021324939.1
• Gene: slc22a5 / 100000685
• ZFINID: ZDB-GENE-091012-1
• Length: 549
• Species: Danio rerio
• Alignment Length: 577
• Identity: 133/577 - (23%)
• Similarity: 225/577 - (38%)
• Gaps: 125/577 - (21%)

  Fly   209 VGQITGPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQTQWIKVS 273
            :|| |||   :.:|...|:.|..|.:......|:|.|.:|.|.   |:    :.......|::.|
Zfish    11 LGQ-TGP---FFIRLFCLLNLIYISTGLHGLYIVFVAASPAHR---CR----VDVNLTEDWLEAS 64

  Fly   274 HPQKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENSD-QEPRVWEKPLHRNSNV----------- 326
            .|.:..|                           |.| |..:.|...|...:|:
Zfish    65 APTETLS---------------------------NGDLQVSQCWRYSLQTLTNLSGQGYSPGQIN 102

  Fly   327 ---IP---CTE-FQHESD-YHS-VVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSP 382
               ||   |.: :.:.:| ||| :|:::||||..:..|.:.......|.|.|.|::.||...|.
Zfish   103 ITDIPRERCEDGWVYSADVYHSTIVSEWDLVCDSEWRVPLASSTLYMGYLLGSIVSGQLSDRFG- 166

  Fly   383 RNVMLFG--------MITQ-------IFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQIMA 432
            |..:|||        |..|       ||| .|...:.::::.::...         :..|.::::
Zfish   167 RKKVLFGSLAAEALLMFAQSFSPSWLIFC-VLYFFIGAFQISLYITA---------FVLGNEVLS 221

  Fly   433 DITGGKYRTCVSTL--FEQFWSIGVMMLPGVASFWSSWSHLYMAISWPTVILIYLWQWIPDSPRW 495
                |..|...:||  |..: .:|.|:||.||.....|..|...:|..||:.|.||..||:||||
Zfish   222 ----GSLRVLFTTLGAFLHY-CVGYMLLPWVAFAIRHWRTLLRVLSGLTVVYIPLWWLIPESPRW 281

  Fly   496 LIARGRTQDAKKILLECVEVNGTGYNLPHDIDQQLELQ-------AQTAMDAPPPSGWWSMWKGE 553
            |:::|..|:::.||.:....|..  ..|..|.:|.:::       ..:|:|....|.
Zfish   282 LLSQGHVQESEAILRDAARKNRV--PAPEVIFKQSQIKEAAFQKSKYSALDVLRTSN-------- 336

  Fly   554 RAVRH--IVCVHLAWSLYIVVYYGMLLNIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRK 616
              :|.  .:|: |.|....:.|:|:.||..:.|.|. ::|.|.:..:|:.......||:....|:
Zfish   337 --IRRTTFMCL-LLWMAINIGYFGLSLNTTNLSGDP-FLNCFLSAVTEVPAYIVSTFLLKSCPRR 397

  Fly   617 WLWTGLFNIVAGCIAYCGWLVPKPSVIGLDPNVALLMCSAMVSKMAISTTLSILTTCTVELVSDD 681
            .:.:. |.::.|.......|:|       |....|.:...|..|...:.:.:::...|.||....
Zfish   398 PVLSA-FLVIGGGFLLLVQLIP-------DRLQTLALALEMAGKFGFTMSFTVVYIYTAELYPTV 454

  Fly   682 KKKITSFSTICWARFWLLGAPFIGSTVVFGQLIPQTAFASLAILGGLCTSLISSPRT 738
            .:.:........||...:.||:|.....|.:.:|.....||.|...|....:  |.|
Zfish   455 LRNLGMGMCSSAARIGSITAPYIIFLGTFNRHLPYVLMGSLTITASLANLFL--PET 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44098	NP_001262264.1	MFS_SLC22	329..732	CDD:340875	104/431 (24%)
slc22a5	XP_021324939.1	MFS_SLC22A4_5_OCTN1_2	104..507	CDD:340934	106/442 (24%)